Emerging research evidence has established the critical role of the gut-liver axis in the development of alcohol-associated liver disease (ALD). The present study employed 16S rRNA gene and whole genome shotgun (WGS) metagenomic analysis in combination ...
Richa Singhal +15 more
doaj +1 more source
Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: A Pharmacokinetic, Microbiome, and Untargeted Metabolomics Study. [PDF]
Determining factors that contribute to interindividual and intra-individual variability in pharmacokinetics (PKs) and drug metabolism is essential for the optimal use of drugs in humans.
Alhaja, Maher +8 more
core +1 more source
Gut microbiota markers in obese adolescent and adult patients: Age-dependent differential patterns [PDF]
Obesity levels, especially in children, have dramatically increased over the last few decades. Recently, several studies highlighted the involvement of gut microbiota in the pathophysiology of obesity. We investigated the composition of gut microbiota in
Alessandra Russo +15 more
core +8 more sources
Background The temporal relationship between adiposity and gut microbiota was unexplored. Whether some gut microbes lie in the pathways from adiposity to insulin resistance is less clear.
Kui Deng +7 more
doaj +1 more source
Intestinal microflora dysbiosis and resistome in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) [PDF]
The aim of the present study is to explore the bacterial diversity within the gut microbiome of chronic inflammatory demyelinating polyneuropathy patient.
Katia Djenadi +8 more
doaj +1 more source
High-throughput sequencing of 16S rRNA gene amplicons : effects of extraction procedure, primer length and annealing temperature [PDF]
The analysis of 16S-rDNA sequences to assess the bacterial community composition of a sample is a widely used technique that has increased with the advent of high throughput sequencing.
Cogan, Tristan +4 more
core +3 more sources
Introduction: With the mounting number of cancer survivors, the complications following cancer treatment become novel conundrums and starve for countermeasures.
Zongkui Wang +14 more
doaj +1 more source
Whole-Genome Sequence of Lachnospiraceae Bacterium NBRC 112778, Isolated from a Mesophilic Methanogenic Bioreactor [PDF]
Here, we report the draft genome sequence of Lachinospiraceae bacterium NBRC 112778. This anaerobic bacterium, isolated from a sweet potato-digesting mesophilic methanogenic bioreactor, represents a new genus related to the genus Anaerosporobacter .
Kohji Morimura, Kenji Uéda
openalex +3 more sources
Mixed Spices at Culinary Doses Have Prebiotic Effects in Healthy Adults: A Pilot Study. [PDF]
Spices were used as food preservatives prior to the advent of refrigeration, suggesting the possibility of effects on microbiota. Previous studies have shown prebiotic activities in animals and in vitro, but there has not been a demonstration of ...
Carpenter, Catherine L +11 more
core +1 more source
Changes in the gut microbiota of mice orally exposed to methylimidazolium ionic liquids [PDF]
Ionic liquids are salts used in a variety of industrial processes, and being relatively non-volatile, are proposed as environmentally-friendly replacements for existing volatile liquids.
Abdelghany, Tarek M. +7 more
core +2 more sources

