Letrozole treatment of pubertal female mice results in activational effects on reproduction, metabolism and the gut microbiome. [PDF]
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductive-aged women that is comprised of two out of the following three features: hyperandrogenism, oligo- or amenorrhea, or polycystic ovaries. In addition to infertility, many women
Arroyo, Pablo +4 more
core +2 more sources
Nod2 Deficiency in mice is Associated with Microbiota Variation Favouring the Expansion of mucosal CD4+ LAP+ Regulatory Cells [PDF]
Nucleotide-binding Oligomerization Domain-2 (NOD2) mutations are associated with an increased risk to develop Crohn's Disease. In previous studies, we have shown that Nod2-/- mice manifest increased proportion of Lamina Propria (LP) CD4+ LAP+ Foxp3 ...
Boirivant, M. +9 more
core +3 more sources
Gut microbiota of migrating wild rabbit fish (Siganus guttatus) larvae have low spatial and temporal variability [PDF]
We investigated the gut microbiota of rabbit fish larvae at three locations in Vietnam (ThuanAn-northern, QuangNam-intermediate, BinhDinh-southern sampling site) over a three-year period. In the wild, the first food for rabbit fish larvae remains unknown,
Boon, Nico +9 more
core +2 more sources
Polysaccharide utilization loci and nutritional specialization in a dominant group of butyrate-producing human colonic Firmicutes [PDF]
Acknowledgements The Rowett Institute of Nutrition and Health (University of Aberdeen) receives financial support from the Scottish Government Rural and Environmental Sciences and Analytical Services (RESAS).
Bernalier-Donadille, Annick +9 more
core +2 more sources
: The chicken microbiota is often analyzed to address questions about the effects of diet or disease on poultry health. To analyze the microbiota, bioinformatic platforms such as QIIME 2 and mothur are used, which incorporate public taxonomic databases ...
Philip M. Campos +3 more
doaj +1 more source
Therapeutic Potential of <i>Irpex lacteus</i> Polysaccharides in Lupus Nephritis: Insights From Gut Microbiota and Metabolomics Analysis in MRL/Lpr Mice. [PDF]
Polysaccharides from Irpex lacteus alleviated kidney inflammatory response. PCP could reverse the phenotype of MRL/lpr mice, reduce autoantibody levels, alleviate inflammatory responses, and improve renal function. Improving the body's metabolism by gut microbes may be the possible mechanism of PCP in treating LN.
Ji G +9 more
europepmc +2 more sources
Beneficial effect of butyrate‐producing Lachnospiraceae on stress‐induced visceral hypersensitivity in rats [PDF]
AbstractBackground and AimEmerging evidence indicates that psychological stress is involved in the pathogenesis of irritable bowel syndrome, which is characterized by visceral hypersensitivity and may be accompanied by gut dysbiosis. However, how such stress contributes to the development of visceral hypersensitivity is incompletely understood.
Zhang, Jindong +7 more
openaire +2 more sources
Discordant transmission of bacteria and viruses from mothers to babies at birth [PDF]
BACKGROUND: The earliest microbial colonizers of the human gut can have life-long consequences for their hosts. Precisely how the neonatal gut bacterial microbiome and virome are initially populated is not well understood.
Handley, Scott A +8 more
core +2 more sources
A total of 208 metabolites and 223 targets were initially extracted from the gutMGene v1.0 database. In addition, 1,630 and 1,321 targets were identified using the Similarity Ensemble Approach and Swiss Target Prediction databases, respectively ...
Si Su +10 more
doaj +1 more source
Dietary intake affects the structure and function of microbes in host intestine. However, the succession of gut microbiota in response to changes in macronutrient levels during a long period of time remains insufficiently studied. Here, we determined the
Yao Tong Hao +12 more
doaj +1 more source

