Results 61 to 70 of about 43,463 (274)

Persistence of Supplemented Bifidobacterium longum subsp. infantis EVC001 in Breastfed Infants. [PDF]

, 2017
Attempts to alter intestinal dysbiosis via administration of probiotics have consistently shown that colonization with the administered microbes is transient. This study sought to determine whether provision of an initial course of Bifidobacterium longum
Andra A. Hutton, Bethany M. Henrick, Carlito B. Lebrilla, Claire A. Shaw, Daniela Barile, David A. Mills, Gege Xu, Giorgio Casaburi, J. Bruce German, Jasmine C. C. Davis, Jennifer T. Smilowitz, Lindsey N. Contreras, Mark A. Underwood, Michelle C. Palumbo, Rosa Krajmalnik-Brown, Samara L. Freeman, Steven A. Frese   +16 more
core   +2 more sources

Acids produced by lactobacilli inhibit the growth of commensal Lachnospiraceae and S24-7 bacteria

Gut Microbes, 2022
The Lactobacillaceae are an intensively studied family of bacteria widely used in fermented food and probiotics, and many are native to the gut and vaginal microbiota of humans and other animals. Various studies have shown that specific Lactobacillaceae species produce metabolites that can inhibit the colonization of fungal and bacterial pathogens, but
Emma J. E. Brownlie, Danica Chaharlangi, Erin Oi-Yan Wong, Deanna Kim, William Wiley Navarre   +4 more
openaire   +3 more sources

miRNA-10a-5p Alleviates Insulin Resistance and Maintains Diurnal Patterns of Triglycerides and Gut Microbiota in High-Fat Diet-Fed Mice

Mediators of Inflammation, 2020
miRNA-10a is rhythmically expressed and regulates genes involved in lipid and glucose metabolism. However, the effects of miRNA-10a on obesity and glucose intolerance, as well as on the diurnal pattern of expression of circadian clock genes, remain ...
Yawei Guo, Xiaohui Zhu, Sha Zeng, Mingyi He, Xiurong Xing, Changyuan Wang   +5 more
doaj   +1 more source

Profiling gut microbiota and bile acid metabolism in critically ill children

Scientific Reports, 2022
Broad-spectrum antimicrobial use during the treatment of critical illness influences gastrointestinal fermentation endpoints, host immune response and metabolic activity including the conversion of primary to secondary bile acids.
Iain Robert Louis Kean, Joseph Wagner, Anisha Wijeyesekera, Marcus De Goffau, Sarah Thurston, John A. Clark, Deborah K. White, Jenna Ridout, Shruti Agrawal, Riaz Kayani, Roddy O’Donnell, Padmanabhan Ramnarayan, Mark J. Peters, Nigel Klein, Elaine Holmes, Julian Parkhill, Stephen Baker, Nazima Pathan   +17 more
doaj   +1 more source

Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs

Advanced Science, EarlyView.
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han, Dae‐Seong Lee, Su‐Won Jeong, Ji‐Hyun Yun, Seomin Kang, Seoyoung Jang, EunAh Lee, Ju Hye Baek, Che Ok Jeon, Jin‐Woo Bae   +9 more
wiley   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source

Effects of synbiotic supplement on human gut microbiota, body composition and weight loss in obesity [PDF]

, 2020
Targeting gut microbiota with synbiotics (probiotic supplements containing prebiotic components) is emerging as a promising intervention in the comprehensive nutritional approach to reducing obesity.
Aljutaily, T., Huarte, E., Sergeev, I. N., Walton, Gemma   +3 more
core   +1 more source

Dietary bioactive lipid compounds rich in menthol alter Interactions among members of ruminal microbiota in sheep [PDF]

, 2019
This study aimed to investigate the effects of two practically relevant doses of menthol-rich plant bioactive lipid compounds (PBLC) on fermentation, microbial community composition, and their interactions in sheep rumen.
Aschenbach, Jörg R., Braun, Hannah-Sophie, Geiger, Sebastian, Park, Tansol, Patra, Amlan K., Pieper, Robert, Yu, Zhongtang   +6 more
core   +1 more source

CRISPR in MOF Formulation with Enhanced Stability, Activity, and Altered PAM Specificity for Broad‐Spectrum Diagnosis of Bacterial Sepsis

Advanced Science, EarlyView.
CRISPR‐FLEXMO (CRISPR with flexible PAM in MOF encapsulation) integrates a PAM‐relaxed Cas12a K607R enzyme with a manganese‐coordinated MOF for broad‐spectrum diagnosis of bacterial sepsis. The MOF enhances activity and preserves functionality under heat, solvent, and chaotropic stress, supporting long‐term room‐temperature storage.
Tathagata Pal, Zilong Liu, Meera G. Nair, Juhong Chen   +3 more
wiley   +1 more source

Aminopeptidase O Protein mediates the association between Lachnospiraceae and appendicular lean mass

Frontiers in Microbiology
ObjectiveInvestigating the causal relationship between Lachnospiraceae and Appendicular lean mass (ALM) and identifying and quantifying the role of Aminopeptidase O Protein (AOPEP) as a potential mediator.MethodsThe summary statistics data of gut ...
Bingjun Gao, Zhonghua Zhou, Junfei Chen, Shengling Zhang, Shaobin Jin, Weiwei Yang, Yinghan Lei, Kunyao Wang, Jinxu Li, Yan Zhuang   +9 more
doaj   +1 more source