Results 71 to 80 of about 43,463 (274)

Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice [PDF]

, 2013
Background: Murine models are a crucial component of gut microbiome research. Unfortunately, a multitude of genetic backgrounds and experimental setups, together with inter-individual variation, complicates cross-study comparisons and a global ...
Brinkman, Brigitta, Cauwe, Benedicte, Garcia Yunta, Roberto, Hildebrand, Falk, Liston, Adrian, Nguyen, (Thi Loan Anh, Raes, Jeroen, Vandenabeele, Peter   +7 more
core   +3 more sources

Engineered Bacteria‐Vesicle Delivered Lactate Reprogramming Boosts Tumor Radiosensitivity

Advanced Science, EarlyView.
We engineered a bacterial‐vesicular dual‐delivery platform that targets LOx to colorectal tumors, enabling lactate clearance, immune microenvironment remodeling, and microbiota modulation. This microbe–metabolism synergistic strategy effectively sensitizes colorectal cancer to radiotherapy, offering a promising approach to overcome radioresistance ...
Fei Peng, Zhe Lei, Zhehao Zhang, Zhiyue Su, Chonghai Zhang, Huan Yang, Shu Liu, Mengyuan Hu, Yuhong Wang, Lingchuan Guo, Lin Hu, Kai Yang   +11 more
wiley   +1 more source

The role of monoammonium glycyrrhizinate as a methane inhibitor to limit the rumen methane emissions of Karakul sheep

Animal
Methane (CH4) from ruminant production systems produces greenhouse gases that contribute to global warming. Our goal was to determine whether monoammonium glycyrrhizinate could inhibit CH4 emissions over the long term without affecting animal performance
Tiantian Bai, Chenyu Jiang, Jishu Wang, Guangxu E, Xuefeng Guo, Junfeng Liu, Van Hung Le, Long Cheng   +7 more
doaj   +1 more source

The CIAMIB: a Large and Metabolically Diverse Collection of Inflammation-Associated Bacteria from the Murine Gut

mBio, 2022
Gut inflammation directly impacts the growth and stability of commensal gut microbes and can lead to long-lasting changes in microbiota composition that can prolong or exacerbate disease states.
Erin Oi-Yan Wong, Emma Joan Elizabeth Brownlie, Katharine Michelle Ng, Sornnujah Kathirgamanathan, Feiqiao Brian Yu, Bryan D. Merrill, Kerwyn Casey Huang, Alberto Martin, Carolina Tropini, William Wiley Navarre   +9 more
doaj   +1 more source

Lachnospiraceae and Bacteroidales Alternative Fecal Indicators Reveal Chronic Human Sewage Contamination in an Urban Harbor [PDF]

Applied and Environmental Microbiology, 2011
ABSTRACT The complexity of fecal microbial communities and overlap among human and other animal sources have made it difficult to identify source-specific fecal indicator bacteria. However, the advent of next-generation sequencing technologies now provides increased sequencing power to resolve microbial community composition ...
Ryan J. Newton, Jessica L. VandeWalle, Mark A. Borchardt, Marc H. Gorelick, Sandra L. McLellan   +4 more
openalex   +4 more sources

16S rRNA gene-based profiling of the human infant gut microbiota is strongly influenced by sample processing and PCR primer choice [PDF]

, 2015
Acknowledgements The authors acknowledge the assistance of Grietje Holtrop (RINH-BioSS) with the statistical analysis of the data and the Wellcome Trust Sanger Institute’s 454 pyrosequencing team for generating 16S rRNA gene data. AWW, PS and JP received
Flint, Harry J., Martin, Jennifer C., Parkhill, Julian, Scott, Karen P., Scott, Paul, Walker, Alan W.   +5 more
core   +2 more sources

Comparison of Pre‐ and Postoperative Gut Microbiota Diversity in Patients With Rectal Cancer Undergoing Stoma Creation and Closure

Annals of Gastroenterological Surgery, EarlyView.
We investigated the impact of temporary stoma creation and closure on gut microbiota diversity in rectal cancer patients. 16S rRNA sequencing revealed that microbial diversity significantly decreased postoperatively in the stoma group but remained stable in non‐stoma patients.
Yusuke Suzuki, Wataru Osumi, Kohei Taniguchi, Nahoko Kato‐Kogoe, Shoichi Sakaguchi, Shota Nakamura, Yoshiro Imai, Takashi Nakano, Takaaki Ueno, Sang‐Woong Lee   +9 more
wiley   +1 more source

Regulation of sleep disorders in patients with traumatic brain injury by intestinal flora based on the background of brain-gut axis

Frontiers in Neuroscience, 2022
ObjectiveThis study investigates whether people with sleep disorders following traumatic brain injury exhibit altered intestinal flora. The changes may allow us to gain a better understanding of the role of intestinal flora in patients with sleep ...
Niu Zhanfeng, Wu Liang, Kang Jing, Bai Jinbo, Chen Yanjun, Xia Hechun   +5 more
doaj   +1 more source

Impact of a GABA-Producing <i>Lactococcus lactis</i> on Microbiota and Mycobiota During CNS Inflammatory Demyelination. [PDF]

FASEB Bioadv
GABA‐producing Lactococcus lactis protects against experimental autoimmune encephalomyelitis (EAE) in a mouse source‐dependent manner. The study focuses on the therapeutic potential of genetically engineered gamma‐aminobutyric acid (GABA)‐overproducing Lactococcus lactis (P8s‐GAD L. lactis) in the EAE model.
Hill K, LaFollette A, Kirby TO, Negrete S, Babcock D, Felton K, Kohl H, Sharma K, Castillo A, Roullet JB, Gibson KM, Ochoa-Repáraz J.   +11 more
europepmc   +2 more sources

Metabolic Comparison of One-Anastomosis Gastric Bypass, Single-Anastomosis Duodenal-Switch, Roux-en-Y Gastric Bypass, and Vertical Sleeve Gastrectomy in Rat [PDF]

, 2018
Background One-anastomosis gastric bypass (OAGB) and single-anastomosis duodenal switch (SADS) have become increasingly popular weight loss strategies. However, data directly comparing the effectiveness of these procedures with Roux-en-Y gastric bypass ...
Arble, Deanna M., Bozadjieva, Nadajda, Evers, Simon S., Frikke-Schmidt, Henriette, Lewis, Alfor, Myronovych, Andriy, Seeley, Randy J., Toure, Mouhamadoul Habib   +7 more
core   +1 more source