Results 131 to 140 of about 204,629 (245)
Translational PBPK Modeling and Exposure‐Response Analysis of AT‐RvD1 for Treating Sjögren's Disease
ABSTRACT Sjögren's disease (SD) is an autoimmune condition characterized by chronic inflammation and impaired secretory function of the salivary glands (SG). The proresolving lipid mediator AT‐RvD1 restores SG function in SD‐like mice; however, its tissue pharmacokinetics, exposure‐response relationships, and human dose predictions remain poorly ...
Venkata K. Yellepeddi +3 more
wiley +1 more source
We present new insights into the internal cranial anatomy of the neosuchian crocodyliform Pholidosaurus purbeckensis, based on CT‐scan data of material from the lowermost Cretaceous Purbeck Limestone Group, southern UK. From the study of the endocast, we obtained new information on the phylogeny and the ecological evolution of the Family ...
Leonardo Barbini +4 more
wiley +1 more source
The aging lacrimal gland: Changes in structure and function
The afferent nerves of the cornea and conjunctiva, efferent nerves of the lacrimal gland, and the lacrimal gland are a functional unit that works cooperatively to produce the aqueous component of tears. A decrease in the lacrimal gland secretory function
DARTT, Darlene A. +3 more
core
IgG4‐related ophthalmic disease comprises four histologic patterns representing progressive fibrosis and sclerosis. Fibrosis is associated with CD163‐positive M2 macrophages and increased TGFB1 expression in lymphocyte‐rich areas, suggesting roles for these components in disease progression.
Natsuki Taniguchi +7 more
wiley +1 more source
ABSTRACT Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign vascular proliferation of unknown origin. It typically occurs in the head and neck region, but can occasionally manifest in unusual locations, such as the penis. Herein, we report a case of ALHE in a 46‐year‐old HIV‐infected male presenting with multiple pruritic whitish ...
Rievanda Ayu Natasya +5 more
wiley +1 more source
Abstract Sjögren's disease is an autoimmune disease characterized by severe dry eye, but its pathophysiology remains unclear. Non‐obese diabetic (NOD) mice develop Sjögren's disease‐like dry eye prior to the onset of diabetes. Although intestinal immune abnormalities precede diabetes in NOD mice, their relationship to dry eye remains poorly understood.
Kenji Goto +3 more
wiley +1 more source
Histopathologically Proven Tarsal Lacrimal Gland Choristoma. [PDF]
Tatlici E +3 more
europepmc +1 more source
Warthin tumor of the lacrimal gland.
To describe a case of Warthin tumor involving the lacrimal gland.Case report. The patient underwent a lateral orbitotomy to remove a nodular lesion involving the lacrimal gland.
STAIBANO S +7 more
core
Orbitocranial resection for treatment of lacrimal gland malignant tumors with intracranial extension. [PDF]
Xia Y +5 more
europepmc +1 more source
A rare case of lacrimal gland adenocarcinoma successfully treated with carbon ion radiotherapy. [PDF]
Benedetto C +6 more
europepmc +1 more source

