Results 131 to 140 of about 204,629 (245)

Translational PBPK Modeling and Exposure‐Response Analysis of AT‐RvD1 for Treating Sjögren's Disease

open access: yesClinical and Translational Science, Volume 19, Issue 10, October 2026.
ABSTRACT Sjögren's disease (SD) is an autoimmune condition characterized by chronic inflammation and impaired secretory function of the salivary glands (SG). The proresolving lipid mediator AT‐RvD1 restores SG function in SD‐like mice; however, its tissue pharmacokinetics, exposure‐response relationships, and human dose predictions remain poorly ...
Venkata K. Yellepeddi   +3 more
wiley   +1 more source

Endocranial anatomy of the earliest Cretaceous European neosuchian crocodyliform Pholidosaurus purbeckensis provides new evidence for the ecological evolution of Pholidosauridae

open access: yesJournal of Anatomy, Volume 249, Issue 4, Page 787-802, October 2026.
We present new insights into the internal cranial anatomy of the neosuchian crocodyliform Pholidosaurus purbeckensis, based on CT‐scan data of material from the lowermost Cretaceous Purbeck Limestone Group, southern UK. From the study of the endocast, we obtained new information on the phylogeny and the ecological evolution of the Family ...
Leonardo Barbini   +4 more
wiley   +1 more source

The aging lacrimal gland: Changes in structure and function

open access: yes, 2016
The afferent nerves of the cornea and conjunctiva, efferent nerves of the lacrimal gland, and the lacrimal gland are a functional unit that works cooperatively to produce the aqueous component of tears. A decrease in the lacrimal gland secretory function
DARTT, Darlene A.   +3 more
core  

Pathological Evolution of Fibrosis in IgG4‐Related Ophthalmic Disease: A Retrospective Study of 100 Cases

open access: yesPathology International, Volume 76, Issue 10, October 2026.
IgG4‐related ophthalmic disease comprises four histologic patterns representing progressive fibrosis and sclerosis. Fibrosis is associated with CD163‐positive M2 macrophages and increased TGFB1 expression in lymphocyte‐rich areas, suggesting roles for these components in disease progression.
Natsuki Taniguchi   +7 more
wiley   +1 more source

Clinical and Diagnostic Insights into Penile Angiolymphoid Hyperplasia with Eosinophilia Based on a Case and Analysis of Previous Literature

open access: yesSkin Research and Technology, Volume 32, Issue 10, October 2026.
ABSTRACT Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign vascular proliferation of unknown origin. It typically occurs in the head and neck region, but can occasionally manifest in unusual locations, such as the penis. Herein, we report a case of ALHE in a 46‐year‐old HIV‐infected male presenting with multiple pruritic whitish ...
Rievanda Ayu Natasya   +5 more
wiley   +1 more source

Pathophysiology of the gut–eye axis in a Sjögren's disease‐like dry eye mouse model: An exploratory evaluation of dietary heat‐treated Enterococcus faecalis FK‐23

open access: yesExperimental Physiology, Volume 111, Issue 10, Page 4507-4524, 1 October 2026.
Abstract Sjögren's disease is an autoimmune disease characterized by severe dry eye, but its pathophysiology remains unclear. Non‐obese diabetic (NOD) mice develop Sjögren's disease‐like dry eye prior to the onset of diabetes. Although intestinal immune abnormalities precede diabetes in NOD mice, their relationship to dry eye remains poorly understood.
Kenji Goto   +3 more
wiley   +1 more source

Histopathologically Proven Tarsal Lacrimal Gland Choristoma. [PDF]

open access: yesBeyoglu Eye J
Tatlici E   +3 more
europepmc   +1 more source

Warthin tumor of the lacrimal gland.

open access: yes, 1997
To describe a case of Warthin tumor involving the lacrimal gland.Case report. The patient underwent a lateral orbitotomy to remove a nodular lesion involving the lacrimal gland.
STAIBANO S   +7 more
core  

A rare case of lacrimal gland adenocarcinoma successfully treated with carbon ion radiotherapy. [PDF]

open access: yesRadiol Case Rep
Benedetto C   +6 more
europepmc   +1 more source

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