Results 151 to 160 of about 12,104 (209)

New insights into lactase and glycosylceramidase activities of rat lactase-phlorizin hydrolase

open access: yesAmerican Journal of Physiology-Gastrointestinal and Liver Physiology, 1989
Lactase-phlorizin hydrolase, a small intestinal disaccharidase, has been considered mainly an enzyme important only for the hydrolysis of lactose. After weaning in most mammals lactase-specific activity falls markedly, and, functionally, adult mammals are considered to be lactase deficient. However, the persistence of low levels of lactase activity in
H A, Büller   +5 more
openaire   +3 more sources

Evolution of lactase persistence: an example of human niche construction [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2011
Niche construction is the process by which organisms construct important components of their local environment in ways that introduce novel selection pressures. Lactase persistence is one of the clearest examples of niche construction in humans.
Pascale Gerbault   +2 more
exaly   +2 more sources

Adult-type hypolactasia and regulation of lactase expression

open access: yesBiochimica Et Biophysica Acta - General Subjects, 2005
Udgivelsesdato: May 25A common genetically determined polymorphism in the human population leads to two distinct phenotypes in adults, lactase persistence and adult-type hypolactasia (lactase non-persistence).
Jesper T Troelsen
exaly   +1 more source
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Human lactase and the molecular basis of lactase persistence

Biochemical Genetics, 1985
Human lactase purified from detergent extracts of the total membrane fraction of postmortem jejunum by means of monoclonal immunoadsorbent chromatography appears to be a dimer of subunits identical in Mr (160K). Trypsin or papain removes a small hydrophobic anchoring peptide from each subunit to give a hydrophilic enzyme which no longer interacts with ...
J, Potter   +5 more
openaire   +2 more sources

On the Evolution of Lactase Persistence in Humans

open access: yesAnnual Review of Genomics and Human Genetics, 2017
Lactase persistence—the ability of adults to digest the lactose in milk—varies widely in frequency across human populations. This trait represents an adaptation to the domestication of dairying animals and the subsequent consumption of their milk.
Laure Segurel, Celine Bon
exaly   +2 more sources

Lactase deficiency in Nigerians

The American Journal of Digestive Diseases, 1971
A combination of lactose and glucose-galactose tolerance tests was carried out on 83 patients to determine the prevalence of isolated lactase deficiency in the the various ethnic groups of Nigerians living in Ibadan. Lactase deficiency was found in 81% of all the subjects.
D A, Olatunbosun, B, Kwaku Adadevoh
openaire   +2 more sources

Occupational sensitization to lactase

American Journal of Industrial Medicine, 1997
Occupational sensitization to lactase is reported in workers formulating and packaging this consumer product, which is used for the relief of gastrointestinal symptoms caused by intolerance to lactose. Allergic rhinitis, conjunctivitis, and some cases of asthma were noted.
D C, Muir   +5 more
openaire   +2 more sources

Lactase Deficiency in Orientals

Gastroenterology, 1968
Summary In our study all 11 healthy Orientals were shown to have isolated small bowel lactase deficiency. Ten Orientals had symptoms after ingesting 50 g of lactose but tolerated modest amounts of milk.
M H, Chung, D B, McGill
openaire   +2 more sources

Lactase activity of microorganisms

Folia Microbiologica, 1978
Sixty-two strains of yeasts, molds and bacteria were screened for lactase (beta-D-galactosidase) activity. Strains exhibiting the enzyme activity were evaluated for cell yield as well as enzyme units available per litre of the medium, per g cell dry weight and per mg protein of their cell-free extracts.
M V, Rao, S M, Dutta
openaire   +2 more sources

Purified lactases versus whole-cell lactases—the winner takes it all

Applied Microbiology and Biotechnology, 2021
Lactose-free dairy products are in great demand worldwide due to the high prevalence of lactose intolerance. To make lactose-free dairy products, commercially available β-galactosidase enzymes, also termed lactases, are used to break down lactose to its constituent monosaccharides, glucose and galactose.
Robin Dorau   +2 more
openaire   +2 more sources

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