Results 211 to 220 of about 25,062 (266)
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On the Evolution of Lactase Persistence in Humans
Annual Review of Genomics and Human Genetics, 2017Lactase persistence—the ability of adults to digest the lactose in milk—varies widely in frequency across human populations. This trait represents an adaptation to the domestication of dairying animals and the subsequent consumption of their milk. Five variants are currently known to underlie this phenotype, which is monogenic in Eurasia but mostly ...
Céline Bon
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Human lactase and the molecular basis of lactase persistence
Biochemical Genetics, 1985Human lactase purified from detergent extracts of the total membrane fraction of postmortem jejunum by means of monoclonal immunoadsorbent chromatography appears to be a dimer of subunits identical in Mr (160K). Trypsin or papain removes a small hydrophobic anchoring peptide from each subunit to give a hydrophilic enzyme which no longer interacts with ...
Anna J. Furth +5 more
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Lactase Insufficiency Revisited
Journal of Pediatric Gastroenterology and Nutrition, 1985The definition of “insufficient” small bowel lactase activity varies greatly among authors. The present study is aimed at redefining lactase insufficiency by comparing intestinal lactase activity and results of the lactose breath hydrogen test. Primary “insufficient” lactase activity was considered to be present when a child with a normal small bowel ...
P Forget +4 more
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Lactase Deficiency in Orientals
Gastroenterology, 1968Summary In our study all 11 healthy Orientals were shown to have isolated small bowel lactase deficiency. Ten Orientals had symptoms after ingesting 50 g of lactose but tolerated modest amounts of milk.
Myung H. Chung, Douglas B. McGill
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Immunocytochemical heterogeneity of lactase-phlorizin hydrolase in adult lactase deficiency [PDF]
Gastroenterology, 1993 Adult lactase deficiency may result either from diminished synthesis of precursor lactase-phlorizin hydrolase (phenotype I deficiency) or from altered posttranslational processing of the precursor protein (phenotype II). The aim of this study was to compare the location of lactase-phlorizin hydrolase along the crypt-villus axis in control with adult ...
Ward A. Olsen +2 more
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Occupational sensitization to lactase
American Journal of Industrial Medicine, 1997Occupational sensitization to lactase is reported in workers formulating and packaging this consumer product, which is used for the relief of gastrointestinal symptoms caused by intolerance to lactose. Allergic rhinitis, conjunctivitis, and some cases of asthma were noted.
Jim A. Julian +5 more
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Lactase activity of microorganisms
Folia Microbiologica, 1978Sixty-two strains of yeasts, molds and bacteria were screened for lactase (beta-D-galactosidase) activity. Strains exhibiting the enzyme activity were evaluated for cell yield as well as enzyme units available per litre of the medium, per g cell dry weight and per mg protein of their cell-free extracts.
S. M. Dutta, M. V. R. Rao
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