Results 1 to 10 of about 345,367 (170)
The lactase persistence genotype is a protective factor for the metabolic syndrome [PDF]
Genetics and Molecular Biology, 2014 The Metabolic Syndrome (MetS) is defined as a pattern of metabolic disturbances, which include central obesity, insulin resistance and hyperglycemia, dyslipidemia, and hypertension.
Deise C. Friedrich +6 more
doaj +12 more sources
The evolution of lactase persistence [PDF]
Antropologia Portuguesa, 2012 Lactase persistence has long been recognized as a striking example of human dietary adaptation to changes in food production habits. The observation that the prevalence of lactase persistence is positively correlated with the cultural history of dairying
Jorge Rocha
doaj +5 more sources
A worldwide correlation of lactase persistence phenotype and genotypes [PDF]
BMC Evolutionary Biology, 2010 Background The ability of adult humans to digest the milk sugar lactose - lactase persistence - is a dominant Mendelian trait that has been a subject of extensive genetic, medical and evolutionary research.
Ingram Catherine JE +4 more
doaj +6 more sources
The origins of lactase persistence in Europe. [PDF]
PLoS Computational Biology, 2009 Lactase persistence (LP) is common among people of European ancestry, but with the exception of some African, Middle Eastern and southern Asian groups, is rare or absent elsewhere in the world.
Yuval Itan +4 more
doaj +10 more sources
Lactase persistence and lipid pathway selection in the Maasai. [PDF]
PLoS ONE, 2012 The Maasai are a pastoral people in Kenya and Tanzania, whose traditional diet of milk, blood and meat is rich in lactose, fat and cholesterol. In spite of this, they have low levels of blood cholesterol, and seldom suffer from gallstones or cardiac ...
Kshitij Wagh +12 more
doaj +6 more sources
Impact of selection and demography on the diffusion of lactase persistence. [PDF]
PLoS ONE, 2009 BACKGROUND:The lactase enzyme allows lactose digestion in fresh milk. Its activity strongly decreases after the weaning phase in most humans, but persists at a high frequency in Europe and some nomadic populations.
Pascale Gerbault +3 more
doaj +8 more sources
Ileal Lactase Expression Associates with Lactase Persistence Genotypes [PDF]
Nutrients, 2021 (1) Background: Lactose digestion depends on persistence genotypes (including rs4988235), the frequency of which exhibits broad geographical variability. However, little is known about the relationship between lactase (LCT) genotypes and intestinal expression of LCT.
Jaroslaw Walkowiak +2 more
exaly +4 more sources
Evolution of lactase persistence: an example of human niche construction [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2011 Niche construction is the process by which organisms construct important components of their local environment in ways that introduce novel selection pressures. Lactase persistence is one of the clearest examples of niche construction in humans.
Mathias Currat +2 more
exaly +7 more sources
Lactase persistence genotypes and malaria susceptibility in Fulani of Mali [PDF]
Malaria Journal, 2011 Background Fulani are a widely spread African ethnic group characterized by lower susceptibility to Plasmodium falciparum, clinical malaria morbidity and higher rate of lactase persistence compared to sympatric tribes.
Dolo Amagana +8 more
doaj +6 more sources
Lactase Persistence Variants in Arabia and in the African Arabs
Human Biology, 2014 Lactase persistence (LP), the state enabling the digestion of milk sugar in adulthood, occurs only in some human populations. The convergent and independent origin of this physiological ability in Europe and Africa is linked with animal domestication that either had started in both places independently or had spread from the Near East by acculturation.
Evelyne Heyer +2 more
exaly +4 more sources