The Phenotype/Genotype Correlation of Lactase Persistence among Omani Adults [PDF]
Oman Medical Journal, 2013 Objective: To examine the correlation of lactase persistence phenotype with genotype in Omani adults.Methods: Lactase persistence phenotype was tested by hydrogen breath test in 52 Omani Adults using the Micro H2 analyzer.
Abdulrahim Al-Abri, Riad Bayoumi
doaj +2 more sources
Dairying, diseases and the evolution of lactase persistence in Europe. [PDF]
Nature, 2022 Evershed RP +108 more
europepmc +2 more sources
Dairy Production and Lactase Persistence in Humans. [PDF]
Anim Front, 2023 europepmc +3 more sources
Ancient DNA analysis reveals high frequency of European lactase persistence allele (T-13910) in medieval central europe. [PDF]
PLoS ONE, 2014 Ruminant milk and dairy products are important food resources in many European, African, and Middle Eastern societies. These regions are also associated with derived genetic variants for lactase persistence.
Annina Krüttli +5 more
doaj +1 more source
Impact of selection and demography on the diffusion of lactase persistence. [PDF]
PLoS ONE, 2009 BACKGROUND:The lactase enzyme allows lactose digestion in fresh milk. Its activity strongly decreases after the weaning phase in most humans, but persists at a high frequency in Europe and some nomadic populations.
Pascale Gerbault +3 more
doaj +1 more source
Very low frequency of the lactase persistence allele LCT-13910T in the Armenian population
Annals of Human Biology, 2022 Primary lactose malabsorption is characterised by a down-regulation of lactase activity after weaning and inability to digest lactose in adulthood. It has been suggested that the historical introduction of dairying led to a positive selection for lactase
Stefan Németh +5 more
doaj +1 more source
Human Genetics: Lactase Persistence in a Battlefield [PDF]
Current Biology, 2020 Lactase persistence is a common genetic trait in Europeans and other pastoralists. New ancient DNA evidence from a Bronze Age battlefield indicates that selection for lactase persistence was strong and on-going in the last 3,000 years.
openaire +3 more sources
Comparative metabolomics in primates reveals the effects of diet and gene regulatory variation on metabolic divergence. [PDF]
, 2014 Human diets differ from those of non-human primates. Among few obvious differences, humans consume more meat than most non-human primates and regularly cook their food.
Blekhman, Ran +5 more
core +2 more sources
Lactase persistence genotypes and malaria susceptibility in Fulani of Mali
Malaria Journal, 2011 Background Fulani are a widely spread African ethnic group characterized by lower susceptibility to Plasmodium falciparum, clinical malaria morbidity and higher rate of lactase persistence compared to sympatric tribes.
Dolo Amagana +8 more
doaj +1 more source
Escape from epigenetic silencing of lactase expression is triggered by a single-nucleotide change [PDF]
, 2016 The importance of subtle gene regulation and epigenetics in determining complex human traits is increasingly being recognized. However, bridging the gaps between environmental, epigenetic and genetic influences and unraveling causal relationships remain ...
Swallow, DM, Troelsen, JT
core +1 more source