Results 31 to 40 of about 345,367 (170)

Dairy Production and Lactase Persistence in Humans [PDF]

Animal Frontiers, 2023
openaire   +3 more sources

Dairying and the evolution and consequences of lactase persistence in humans [PDF]

Animal Frontiers, 2023
Jay T Stock, Jonathan C K Wells
openaire   +4 more sources

Population history and genetic adaptation of the Fulani nomads: inferences from genome-wide data and the lactase persistence trait [PDF]

BMC Genomics, 2019
Background Human population history in the Holocene was profoundly impacted by changes in lifestyle following the invention and adoption of food-production practices.
Mário Vicente, Edita Priehodová, Issa Diallo, Eliška Podgorná, Estella S. Poloni, Viktor Černý, Carina M. Schlebusch   +6 more
doaj   +2 more sources

Very low frequency of the lactase persistence allele LCT-13910T in the Armenian population

Annals of Human Biology, 2022
Primary lactose malabsorption is characterised by a down-regulation of lactase activity after weaning and inability to digest lactose in adulthood. It has been suggested that the historical introduction of dairying led to a positive selection for lactase
Stefan Németh, Gernot Kriegshäuser, Kristine Hovhannesyan, Hasmik Hayrapetyan, Christian Oberkanins, Tamara Sarkisian   +5 more
doaj   +1 more source

Frequency of lactase persistence genotype in a healthy Polish population

Open Life Sciences, 2011
The majority of mammals are unable to digest lactose due to post-weaning deactivation of the LCT gene, which is responsible for encoding the enzyme lactase (i.e., adult-type hypolactasia).
Płoszaj Tomasz, Jędrychowska-Dańska Krystyna, Witas Henryk   +2 more
doaj   +2 more sources

Effects of the lactase 13910 C/T and calcium-sensor receptor A986S G/T gene polymorphisms on the incidence and recurrence of colorectal cancer in Hungarian population [PDF]

, 2008
Background: Epidemiological studies suggested the chemopreventive role of higher calcium intake in colorectal carcinogenesis. We examined genetic polymorphisms that might influence calcium metabolism: lactase (LCT) gene 13910 C/T polymorphism causing ...
Balla Bernadett, Krisztián Bácsi, Bácsi, Krisztián, Lakatos Péter, Barna Budai, Péter L Lakatos, Balla, Bernadett, Budai Barna, Gábor Speer, Horváth, Henrik Csaba, Péter Lakatos, Erika Hitre, Speer, Gábor, Henrik Horváth, Áron Lazáry, Speer Gábor, Lazáry, Áron, Lakatos, Péter László, Hitre Erika, Kósa János P, Lazáry Áron, Lakatos, Péter, Bernadett Balla, Hitre, E., Bácsi Krisztián, Lakatos Péter L, János P Kósa, Kósa, János, Horváth Henrik   +28 more
core   +2 more sources

The evolution of lactase persistence in Europe. A synthesis of archaeological and genetic evidence

, 2012
Lactase persistence, the ability to digest the milk sugar lactose in adulthood, is highly associated with a T allele situated 13,910 bp upstream from the actual lactase gene in Europeans.
Thomas, M.G., Leonardi, M, Gerbault, P., Burger, J.   +3 more
core   +2 more sources

Dairying history and the evolution of lactase persistence [PDF]

, 2017
Ce chapitre présente des données archéologiques et biologiques permettant de retracer l’histoire de l’utilisation des laitages et l’évolution de la persistance de l’enzyme lactase, responsable de la digestion du lactose, dans les populations européennes.
Mélanie Roffet-Salque, Roffet-Salque, M., Gerbault, Pascale, Roffet-Salque, Melanie, Pascale Gerbault, Gerbault, P.   +5 more
core   +1 more source

Several different lactase persistence associated alleles and high diversity of the lactase gene in the admixed Brazilian population. [PDF]

PLoS ONE, 2012
Adult-type hypolactasia is a common phenotype caused by the lactase enzyme deficiency. The -13910 C>T polymorphism, located 14 Kb upstream of the lactase gene (LCT) in the MCM6 gene was associated with lactase persistence (LP) in Europeans.
Deise C Friedrich, Sidney E B Santos, Ândrea K C Ribeiro-dos-Santos, Mara H Hutz   +3 more
doaj   +1 more source

Genetic adult lactase persistence is associated with risk of Crohn's Disease in a New Zealand population

BMC Research Notes, 2010
Background Mycobacterium avium subspecies paratuberculosis (MAP) is an infective agent found in ruminants and milk products, which has been suggested to increase the risk of gastrointestinal inflammation in genetically susceptible hosts.
Morgan Angharad R, Lam Wen, Han Dug, Nolan Deborah J, Fraser Alan G, Tapsell Linda C, Ferguson Lynnette R   +6 more
doaj   +1 more source