Results 51 to 60 of about 1,930 (158)

The Geographical Distribution of Lactose Tolerance‐Associated Alleles 13910*T and 13915*G Is Strongly Linked to Male Founder Events in Eurasia

American Journal of Human Biology, Volume 38, Issue 5, May 2026.
ABSTRACT Lactose tolerance (lactase persistence) represents a very progressive human adaptation, the origins of which remain incompletely understood. This study aims to examine the geographical distribution of the two alleles associated with lactose tolerance in Eurasia (13910*T and 13915*G) in relation to the main Y haplogroups and autosomal ancestry ...
Pavel Grasgruber
wiley   +1 more source

Lactase non-persistence and milk consumption in Estonia

World Journal of Gastroenterology, 2006
To define the frequency of the C/T-13910 variant associated with lactase persistence/non-persistence trait and to analyze the milk consumption of lactase non-persistent subjects in Estonia.We genotyped 355 Estonians by polymerase chain reaction and direct sequencing.
Margus, Lember, Suvi, Torniainen, Mart, Kull, Riina, Kallikorm, Peeter, Saadla, Tarvo, Rajasalu, Hanna, Komu, Irma, Järvelä   +7 more
openaire   +2 more sources

Dairy Intake and Type 2 Diabetes Mellitus in Iranian Older Adults: Insights From the Baseline Phase of the Birjand Longitudinal Aging Study

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 3, May 2026.
Among 1348 Iranian adults aged ≥ 60 years in the BLAS baseline, total dairy intake showed no clear association with prevalent T2DM (adjusted OR: 1.42, p = 0.05). Higher yogurt (OR: 1.48–1.54) and cheese (OR: 1.44) intakes were linked to greater odds, whereas milk was not.
Mahboubeh Darabi, Amirmohammad Tajik, Mehraneh Movahedi Aliabadi, Zeinab Shakeri, Maryam Mohammadi, Hossein Fakhrzadeh, Mitra Moudi, Masoumeh Khorashadizadeh, Mehdi Varmaghani, Farshad Sharifi   +9 more
wiley   +1 more source

Screening of variants for lactase persistence/non-persistence in populations from South Africa and Ghana

BMC Genetics, 2009
Background Lactase non-persistence is a condition where lactase activity is decreased in the intestinal wall after weaning. In European derived populations a single nucleotide polymorphism (SNP) C/T-13910 residing 13.9 kb upstream from the lactase gene ...
Dandara Collet, Holmberg Ville, Lahtela Elisa, Parker M Iqbal, Torniainen Suvi, Jarvela Irma   +5 more
doaj   +1 more source

Genetiс aspects of lactase persistence in different ethnic groups

Фактори експериментальної еволюції організмів, 2020
Aim. The aim of this study was evaluation of the genetic aspects of lactase persistence (LP) in persons from different ethnic groups. Methods. Genealogical and medical information was collected about Ukrainian, Indian, Nigerian, Israel, Egypt, Palestine,
V. V. Borozenets, V. O. Babalian, O. M. Fedota   +2 more
doaj   +1 more source

Comparison of Quick Lactose Intolerance Test in duodenal biopsies of dyspeptic patients with single nucleotide polymorphism LCT-13910C>T associated with primary hypolactasia/lactase-persistence [PDF]

Acta Cirúrgica Brasileira, 2013
PURPOSE: To analyze the usefulness of Quick Lactose Intolerance Test in relation to the genetic test based on LCT-13910C>T genotypes, previously validated for clinical practice, for primary hypolactasia/lactase-persistence diagnosis.
Rejane Mattar, Anibal Basile-Filho, Rafael Kemp, José Sebastião dos Santos   +3 more
doaj   +1 more source

Enhanced Bioactivity of Puerariae Radix‐ Hovenia Seed Extracts Through Lactiplantibacillus plantarum and Lacticaseibacillus paracasei Co‐Fermentation: Impact on Alcoholic Liver Injury and Macrophage Polarization

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Puerariae Radix and Hovenia Seed were co‐fermented with Lactiplantibacillus plantarum and Lacticaseibacillus paracasei to produce PHF. In a mouse model of alcohol‐induced liver injury, PHF intervention alleviated liver damage. The underlying mechanism may be related to the regulation of macrophage polarization.
Yunpeng Sun, Shen Yao, Yuan Cui, Yiyu Ni, Meichen Liu, Daqing Zhao, Shiting Yu, Siming Wang   +7 more
wiley   +1 more source

High prevalence of lactase non-persistence among indigenous nomadic Nenets, north-west Russia [PDF]

International Journal of Circumpolar Health, 2012
Objectives. The frequency of adult-type hypolactasia (lactase non-persistence) varies widely among different ethnic groups. The cultural historical hypothesis assumes a link between the occurrence of hypolactasia and the distribution of dairy farming ...
Yulia Khabarova, Valentina Grigoryeva, Sari Tuomisto, Pekka J. Karhunen, Kari Mattila, Mauri Isokoski   +5 more
doaj   +1 more source

PERCC1‐associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide

JPGN Reports, Volume 7, Issue 2, Page 266-270, May 2026.
Abstract Congenital diarrheas and enteropathies (CODE) are rare inherited disorders characterized by early‐onset intractable diarrhea. Though progress has been made in elucidating the genetic basis of CODE, much remains to be discovered. Another challenge is the lack of curative therapies—treatment is primarily supportive including enteral and ...
Angela Tran, Vivien Nguyen, Phuong Huynh
wiley   +1 more source

Homo sapiens, industrialisation and the environmental mismatch hypothesis

Biological Reviews, Volume 101, Issue 2, Page 580-601, April 2026.
ABSTRACT For the vast majority of the evolutionary history of Homo sapiens, a range of natural environments defined the parameters within which selection shaped human biology. Although human‐induced alterations to the terrestrial biosphere have been evident for over 10,000 years, the pace and scale of change has accelerated dramatically since the onset
Daniel P. Longman, Colin N. Shaw
wiley   +1 more source