Results 41 to 50 of about 1,908 (139)

Genetic diversity of lactase persistence in East African populations. [PDF]

BMC Res Notes, 2016
The expression of lactase which digests lactose from milk in humans is generally lost after weaning, but selected mutations influencing the promoter of the lactase gene have spread into the human populations. This is considered a classical example of gene-culture co-evolution, and several studies suggested that the lactase gene has been under strong ...
Hassan HY, van Erp A, Jaeger M, Tahir H, Oosting M, Joosten LA, Netea MG.   +6 more
europepmc   +6 more sources

Frequency of LCT -13910C>T single nucleotide polymorphism associated with adult-type hypolactasia/lactase persistence among Brazilians of different ethnic groups

Nutrition Journal, 2009
Background Adult-type hypolactasia, the physiological decline of lactase some time after weaning, was previously associated with the LCT -13910C>T polymorphism worldwide except in Africa.
Silva Joyce MK, Santos Aníbal F, Villares Cibele A, Monteiro Maria S, Mattar Rejane, Carrilho Flair J   +5 more
doaj   +1 more source

Diagnosis of adult-type hypolactasia/lactase persistence: genotyping of single nucleotide polymorphism (SNP C/T-13910) is not consistent with breath test in Colombian Caribbean population

Arquivos de Gastroenterologia, 2012
CONTEXT: Genotyping of single nucleotide polymorphism (SNP C/T-13910) located upstream of the lactase gene is used to determine adult-type hypolactasia/lactase persistence in North-European Caucasian subjects.
Evelyn Mendoza Torres, Lourdes Luz Varela Prieto, José Luis Villarreal Camacho, Daniel Antonio Villanueva Torregroza   +3 more
doaj   +1 more source

Lactase non-persistence and milk consumption in Estonia

World Journal of Gastroenterology, 2006
To define the frequency of the C/T-13910 variant associated with lactase persistence/non-persistence trait and to analyze the milk consumption of lactase non-persistent subjects in Estonia.We genotyped 355 Estonians by polymerase chain reaction and direct sequencing.
Margus, Lember, Suvi, Torniainen, Mart, Kull, Riina, Kallikorm, Peeter, Saadla, Tarvo, Rajasalu, Hanna, Komu, Irma, Järvelä   +7 more
openaire   +2 more sources

Screening of variants for lactase persistence/non-persistence in populations from South Africa and Ghana

BMC Genetics, 2009
Background Lactase non-persistence is a condition where lactase activity is decreased in the intestinal wall after weaning. In European derived populations a single nucleotide polymorphism (SNP) C/T-13910 residing 13.9 kb upstream from the lactase gene ...
Dandara Collet, Holmberg Ville, Lahtela Elisa, Parker M Iqbal, Torniainen Suvi, Jarvela Irma   +5 more
doaj   +1 more source

Comparison of Quick Lactose Intolerance Test in duodenal biopsies of dyspeptic patients with single nucleotide polymorphism LCT-13910C>T associated with primary hypolactasia/lactase-persistence [PDF]

Acta Cirúrgica Brasileira, 2013
PURPOSE: To analyze the usefulness of Quick Lactose Intolerance Test in relation to the genetic test based on LCT-13910C>T genotypes, previously validated for clinical practice, for primary hypolactasia/lactase-persistence diagnosis.
Rejane Mattar, Anibal Basile-Filho, Rafael Kemp, José Sebastião dos Santos   +3 more
doaj   +1 more source

Genetiс aspects of lactase persistence in different ethnic groups

Фактори експериментальної еволюції організмів, 2020
Aim. The aim of this study was evaluation of the genetic aspects of lactase persistence (LP) in persons from different ethnic groups. Methods. Genealogical and medical information was collected about Ukrainian, Indian, Nigerian, Israel, Egypt, Palestine,
V. V. Borozenets, V. O. Babalian, O. M. Fedota   +2 more
doaj   +1 more source

High prevalence of lactase non-persistence among indigenous nomadic Nenets, north-west Russia [PDF]

International Journal of Circumpolar Health, 2012
Objectives. The frequency of adult-type hypolactasia (lactase non-persistence) varies widely among different ethnic groups. The cultural historical hypothesis assumes a link between the occurrence of hypolactasia and the distribution of dairy farming ...
Yulia Khabarova, Valentina Grigoryeva, Sari Tuomisto, Pekka J. Karhunen, Kari Mattila, Mauri Isokoski   +5 more
doaj   +1 more source

Lactase Persistence Variants in Arabia and in the African Arabs

Human Biology, 2014
Lactase persistence (LP), the state enabling the digestion of milk sugar in adulthood, occurs only in some human populations. The convergent and independent origin of this physiological ability in Europe and Africa is linked with animal domestication that either had started in both places independently or had spread from the Near East by acculturation.
Edita, Priehodová, Abdelhay, Abdelsawy, Evelyne, Heyer, Viktor, Cerný   +3 more
openaire   +3 more sources

Genetic and cultural adaptations underlie the establishment of dairy pastoralism in the Tibetan Plateau

BMC Biology, 2023
Background Domestication and introduction of dairy animals facilitated the permanent human occupation of the Tibetan Plateau. Yet the history of dairy pastoralism in the Tibetan Plateau remains poorly understood.
Min-Sheng Peng, Yan-Hu Liu, Quan-Kuan Shen, Xiao-Hua Zhang, Jiajia Dong, Jin-Xiu Li, Hui Zhao, Hui Zhang, Xiaoming Zhang, Yaoxi He, Hong Shi, Chaoying Cui, Ouzhuluobu, Tian-Yi Wu, Shi-Ming Liu, Gonggalanzi, Baimakangzhuo, Caijuan Bai, Duojizhuoma, Ti Liu, Shan-Shan Dai, Robert W. Murphy, Xue-Bin Qi, Guanghui Dong, Bing Su, Ya-Ping Zhang   +25 more
doaj   +1 more source