Results 71 to 80 of about 5,485 (192)

Phylogenetic analysis of the evolution of lactose digestion in adults [PDF]

, 1997
In most of the world's population the ability to digest lactose declines sharply after infancy, High lactose digestion capacity in adults is common only in populations of European and circum-Mediterranean origin and is thought to be an evolutionary ...
Holden, C, Mace, R
core  

Lactase non-persistence and milk consumption in Estonia

World Journal of Gastroenterology, 2006
To define the frequency of the C/T-13910 variant associated with lactase persistence/non-persistence trait and to analyze the milk consumption of lactase non-persistent subjects in Estonia.We genotyped 355 Estonians by polymerase chain reaction and direct sequencing.
Margus, Lember, Suvi, Torniainen, Mart, Kull, Riina, Kallikorm, Peeter, Saadla, Tarvo, Rajasalu, Hanna, Komu, Irma, Järvelä   +7 more
openaire   +2 more sources

Positive selection on loci associated with drug and alcohol dependence [PDF]

, 2015
Much of the evolution of human behavior remains a mystery, including how certain disadvantageous behaviors are so prevalent. Nicotine addiction is one such phenotype.
Brooks, Andy, Edenberg, Howard, Goate, Alison, Haller, Gabe, Kramer, John, Nurnberger, John, Sadler, Brooke, Schuckit, Marc, Tischfield, Jay   +8 more
core   +9 more sources

Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review

International Journal of Dermatology, Volume 65, Issue 4, Page 706-723, April 2026.
ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska, Isha Gandhi, Robert Adler, Deena Fayyad, Perya Bhagchandani, Shabnam Afzal, Waleed Adawi, Shivani Patel, Shawn G. Kwatra   +8 more
wiley   +1 more source

Congenital sucrase-isomaltase deficiency presenting with failure to thrive, hypercalcemia, and nephrocalcinosis [PDF]

, 2002
Background Disaccharide Intolerance Type I (Mendelian Interance in Man database: *222900) is a rare inborn error of metabolism resulting from mutation in sucrase-isomaltase (Enzyme Catalyzed 3.2.1.48).
Morriss Michael C, Moore Warren H, Baker Susan S, Taylor William, Reid Barbara, Belmont John W, Podrebarac Susan M, Glass Nancy, Schwartz I David   +8 more
core   +1 more source

Molecular Pharming: Advances, Applications, and Future Prospects in Biotechnology and Medicine

Engineering in Life Sciences, Volume 26, Issue 3, March 2026.
ABSTRACT Genetically engineered plants incorporate the use of a novel bioreactor known as molecular pharming, which has a transformative view on the pharmaceutical industry. The technique enables mass production, at a low cost, and reproducibly of a large number of different protein‐based drugs, vaccines, and industrial enzymes. This review‐based study
Md. Hridoy Ahmed, Md. Mustak Khan, Shishir Dutta, Md. Foyzur Rahman, Mohammad Shariful Islam, Md. Najmul Hosen, Md. Saad Hossain, Md. Aftabur Rahman, Md. Sadman Hasan Sahil, Tanjuma Tasnim Hira, Ifthesum, Ashikur Rahaman, Md. Afser Rabbi, Laila Khaleda   +13 more
wiley   +1 more source

Comparison of Quick Lactose Intolerance Test in duodenal biopsies of dyspeptic patients with single nucleotide polymorphism LCT-13910C>T associated with primary hypolactasia/lactase-persistence [PDF]

Acta Cirúrgica Brasileira, 2013
PURPOSE: To analyze the usefulness of Quick Lactose Intolerance Test in relation to the genetic test based on LCT-13910C>T genotypes, previously validated for clinical practice, for primary hypolactasia/lactase-persistence diagnosis.
Rejane Mattar, Anibal Basile-Filho, Rafael Kemp, José Sebastião dos Santos   +3 more
doaj   +1 more source

Screening of variants for lactase persistence/non-persistence in populations from South Africa and Ghana

BMC Genetics, 2009
Background Lactase non-persistence is a condition where lactase activity is decreased in the intestinal wall after weaning. In European derived populations a single nucleotide polymorphism (SNP) C/T-13910 residing 13.9 kb upstream from the lactase gene ...
Dandara Collet, Holmberg Ville, Lahtela Elisa, Parker M Iqbal, Torniainen Suvi, Jarvela Irma   +5 more
doaj   +1 more source

High prevalence of lactase non-persistence among indigenous nomadic Nenets, north-west Russia [PDF]

International Journal of Circumpolar Health, 2012
Objectives. The frequency of adult-type hypolactasia (lactase non-persistence) varies widely among different ethnic groups. The cultural historical hypothesis assumes a link between the occurrence of hypolactasia and the distribution of dairy farming ...
Yulia Khabarova, Valentina Grigoryeva, Sari Tuomisto, Pekka J. Karhunen, Kari Mattila, Mauri Isokoski   +5 more
doaj   +1 more source

European Society for the Study of Coeliac Disease (ESsCD) 2025 Updated Guidelines on the Diagnosis and Management of Coeliac Disease in Adults. Part 2: Management, Follow‐Up, and Complex Disease Courses

United European Gastroenterology Journal, Volume 14, Issue 2, March 2026.
ABSTRACT Introduction Since the publication of the first European Society for the Study of Coeliac Disease (ESsCD) guidelines in 2019, substantial advances have been made in understanding the management and complex disease courses of coeliac disease (CeD) in adults.
Abdulbaqi Al‐Toma, Federica Branchi, Fabiana Zingone, Annalisa Schiepatti, Georgia Malamut, Cristina Canova, Isabella Rosato, Honoria Ocagli, Nick Trott, Luca Elli, Alina Popp, Carmen Gianfrani, Renata Auricchio, Andra Neefjes‐Borst, David S. Sanders, Christophe Cellier, Chris J. Mulder, Gerd Bouma, Knut E. A. Lundin, Ludvig M. Sollid, Michael Schumann   +20 more
wiley   +1 more source