The origins of lactase persistence in Europe. [PDF]
PLoS Computational Biology, 2009 Lactase persistence (LP) is common among people of European ancestry, but with the exception of some African, Middle Eastern and southern Asian groups, is rare or absent elsewhere in the world.
Yuval Itan +4 more
doaj +10 more sources
A worldwide correlation of lactase persistence phenotype and genotypes [PDF]
BMC Evolutionary Biology, 2010 Background The ability of adult humans to digest the milk sugar lactose - lactase persistence - is a dominant Mendelian trait that has been a subject of extensive genetic, medical and evolutionary research.
Ingram Catherine JE +4 more
doaj +6 more sources
Impact of selection and demography on the diffusion of lactase persistence. [PDF]
PLoS ONE, 2009 BACKGROUND:The lactase enzyme allows lactose digestion in fresh milk. Its activity strongly decreases after the weaning phase in most humans, but persists at a high frequency in Europe and some nomadic populations.
Pascale Gerbault +3 more
doaj +8 more sources
The evolution of lactase persistence [PDF]
Antropologia Portuguesa, 2012 Lactase persistence has long been recognized as a striking example of human dietary adaptation to changes in food production habits. The observation that the prevalence of lactase persistence is positively correlated with the cultural history of dairying
Jorge Rocha
doaj +5 more sources
Lactase persistence genotypes and malaria susceptibility in Fulani of Mali [PDF]
Malaria Journal, 2011 Background Fulani are a widely spread African ethnic group characterized by lower susceptibility to Plasmodium falciparum, clinical malaria morbidity and higher rate of lactase persistence compared to sympatric tribes.
Dolo Amagana +8 more
doaj +6 more sources
Ileal Lactase Expression Associates with Lactase Persistence Genotypes [PDF]
Nutrients, 2021 (1) Background: Lactose digestion depends on persistence genotypes (including rs4988235), the frequency of which exhibits broad geographical variability. However, little is known about the relationship between lactase (LCT) genotypes and intestinal expression of LCT.
Jaroslaw Walkowiak +2 more
exaly +4 more sources
Human Genetics: Lactase Persistence in a Battlefield [PDF]
Current Biology, 2020 Lactase persistence is a common genetic trait in Europeans and other pastoralists. New ancient DNA evidence from a Bronze Age battlefield indicates that selection for lactase persistence was strong and on-going in the last 3,000 ...
Saag, L
core +6 more sources
The onset of lactase persistence in Europe [PDF]
Human Heredity, 2013 The genomic region containing the lactase (LCT) gene shows one of the strongest signals of positive selection in Europeans, detectable using a range of approaches including haplotype length, linked microsatellite variation and population-differentiation ...
Gerbault, P.
core +3 more sources
Lactase persistence and milk consumption in Europe: an interdisciplinary approach involving genetics and archaeology [PDF]
Documenta Praehistorica, 2013 The ability to digest milk during adulthood (lactase persistence) is a genetically determined trait present only in humans. Its origin and diffusion are correlated with the development of pastoralism and the consumption of fresh milk.
Michela Leonardi
doaj +2 more sources
Ancient DNA analysis reveals high frequency of European lactase persistence allele (T-13910) in medieval central europe. [PDF]
PLoS ONE, 2014 Ruminant milk and dairy products are important food resources in many European, African, and Middle Eastern societies. These regions are also associated with derived genetic variants for lactase persistence.
Annina Krüttli +5 more
doaj +5 more sources