Results 91 to 100 of about 778,516 (343)

Lactate signalling regulates fungal β-glucan masking and immune evasion [PDF]

, 2016
AJPB: This work was supported by the European Research Council (STRIFE, ERC- 2009-AdG-249793), The UK Medical Research Council (MR/M026663/1), the UK Biotechnology and Biological Research Council (BB/K017365/1), the Wellcome Trust (080088; 097377).
A Hopke, B Ferwerda, BN Gantner, C Kuei, CA Johnston, CA Munro, CA Rappleye, CJ Barelle, CJ Heilmann, DH Owen, DO Inglis, E Leberer, FN Gravelat, G Bindea, GD Brown, GJ Sosinska, HJ Flint, I Jacobs, ID Iliev, IV Ene, IV Ene, IV Ene, IV Ene, JE Nett, JM Bain, K Lemaire, LE Lewis, LM Graham, M Galán-Díez, M Karababa, M Santos, MG Netea, MG Netea, MJ Marakalala, MM Maidan, MT Kelly, N Vieira, NAR Gow, P Shannon, PR Desai, RA Hall, RT Wheeler, RT Wheeler, RT Wheeler, S Lev, S Shahana, SdJ Carrion, SE Hardison, SM Noble, TR O'Meara, YL Chen   +50 more
core   +1 more source

Marked Long‐term Improvement in Lung Function in Melanoma Differentiation‐associated Protein 5 (MDA5) Antibody Positive Dermatomyositis Patients: Experience of a Single Center Longitudinal Cohort in North America

Arthritis Care &Research, Accepted Article.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation‐associated gene 5 antibody (MDA5 ab) associated dermatomyositis (DM). Methods Thirty patients with MDA5 ab DM were identified in a single center longitudinal cohort of 352 patients with ...
Jenice X Cheah, Sangmee S Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

QSOFA SCORE FOR DIAGNOSTICS OF SEPSIS. RESULTS OF THE RUSSIAN MULTI-CENTER TRIAL OF RISES

Вестник анестезиологии и реаниматологии, 2018
Subjects and methods. The multi-center, prospective, and observational trial was conducted. The following data were analyzed in the patients admitted to intensive care wards: number of qSOFAscores, the presence of SIRS criteria, levels of lactate ...
M. N. Astafieva, V. A. Rudnov, V. V. Kulаbukhov, V. A. Bаgin, N. A. Zubаrevа, M. A. Tribulev, S. Yu. Mukhаchevа   +6 more
doaj   +1 more source

Influence of recovery intensity on oxygen demand and repeated sprint performance [PDF]

, 2016
AIM: This study aimed to determine effects of recovery intensity (passive, 20, 30 and 40%V̇ O2peak) on oxygen uptake kinetics, performance and blood lactate accumulation during repeated sprints.
Babraj, J., Yamagishi, T.
core   +1 more source

Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME

Advanced Functional Materials, EarlyView.
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li, E Pang, Snehasish Debnath, Jia Hong, Aojun Qiu, Dongeun Kim, Goeun Kim, Minhuan Lan, Min‐Goo Lee, Qian‐Yong Cao, Jong Seung Kim   +10 more
wiley   +1 more source

IMPACT OF PYRUVATE CONCENTRATION IN BLOOD ON THE DEVELOPMENT OF POST-PERFUSION CARDIAC FAILURE IN MYOCARDIAL REVASCULIZATION SURGERY WITH CARDIOPULMONARY BYPASS

Вестник анестезиологии и реаниматологии, 2018
Goal of the study: to evaluate the capability of pyruvate which is endogenously produced during myocardium anoxia to prevent the post-perfusion cardiac failure in the patients undergoing revasculization surgery with cardiopulmonary bypass.
N. S. Molchan, A. A. Zhloba, Yu. S. Polushin, M. Yu. Shiganov, A. E. Kobak, A. A. Khryapa, I. V. Tretyakova   +6 more
doaj   +1 more source

GLUT1 expression patterns in different Hodgkin lymphoma subtypes and progressively transformed germinal centers [PDF]

, 2012
Background: Increased glycolytic activity is a hallmark of cancer, allowing staging and restaging with 18F-fluorodeoxyglucose-positron-emission-tomography (PET).
Agostinelli, Claudio, Bergmann, Lothar, Diener, Jürgen, Döring, Claudia, Fanti, Stefano, Gallamini, Andrea, Hansmann, Martin-Leo, Hartmann, Sylvia, Pileri, Stefano, Zinzani, Pier Luigi   +9 more
core   +1 more source

Insight into the Internal Structure of Biogenic, Synthetic and Geological Apatite by Electron Microscopy and X‐Ray Scattering

Advanced Functional Materials, EarlyView.
Apatite occurs in many forms in nature, e.g. in teeth and geological minerals. Internally, biological apatite contains nanocrystals that are also found in synthetically prepared calcium phosphate nanoparticles which are used in biomedicine, e.g. for gene and drug delivery and for bone regeneration. Abstract Calcium phosphate is the inorganic component (
Kathrin Kostka, Oleg Prymak, Kateryna Loza, Matthias Epple   +3 more
wiley   +1 more source

In vivo metabolic imaging of Traumatic Brain Injury. [PDF]

, 2017
Complex alterations in cerebral energetic metabolism arise after traumatic brain injury (TBI). To date, methods allowing for metabolic evaluation are highly invasive, limiting our understanding of metabolic impairments associated with TBI pathogenesis ...
Chaumeil, Myriam M, Chou, Austin, Feng, Xi, Guglielmetti, Caroline, Krukowski, Karen, Najac, Chloe, Riparip, Lara-Kirstie, Rosi, Susanna   +7 more
core   +2 more sources

Microplastics from Wearable Bioelectronic Devices: Sources, Risks, and Sustainable Solutions

Advanced Functional Materials, EarlyView.
Bioelectronic devices (e.g., e‐skins) heavily rely on polymers that at the end of their life cycle will generate microplastics. For research, a holistic approach to viewing the full impact of such devices cannot be overlooked. The potential for devices as sources for microplastics is raised, with mitigation strategies surrounding polysaccharide and ...
Conor S. Boland
wiley   +1 more source