Results 71 to 80 of about 568,053 (260)

Effect of site of lactate infusion on regional lactate exchange in pigs [PDF]

, 2010
BACKGROUND: The rate of extra-hepatic lactate production and the route of influx of lactate to the liver may influence both hepatic and extra-hepatic lactate exchange.
Barthelmes, Daniel; https://orcid.org/, Ahonen, H, Laitinen, S, Rahikainen, S, Takala, Jukka, S Rahikainen, S Laitinen, J Takala, S.M. Jakob, H Ahonen, Jakob, S M, Ahonen, Hanna-Mari, Takala, J, Barthelmes, D, D Barthelmes, Jakob SM, Barthelmes D, Ahonen H, Laitinen S, Rahikainen S, Takala J   +20 more
core   +2 more sources

Generative Artificial Intelligence Utilization and Perspectives Among Reproductive‐Age Women With Systemic Autoimmune and Rheumatic Diseases

Arthritis Care &Research, EarlyView.
Objective Reproductive‐age women with systemic autoimmune and rheumatic diseases (SARDs) have unique information needs related to their SARDs and reproductive health. We sought to understand their use of and receptivity to current and hypothetical generative artificial intelligence (AI) tools for health information‐seeking. Methods We conducted a cross‐
Mariam Arif, Catherine Wright, Samantha Rodriguez, Sarah Graves, Tamar Krishnamurti, Mehret Birru Talabi   +5 more
wiley   +1 more source

Dirac‐Source Linear X‐Ray Detection Diode

Advanced Functional Materials, EarlyView.
Monolayer graphene imparts near linear current‐voltage behavior to a perovskite X‐ray detection diode, contrasting with conventional diode‐like responses. Exploiting graphene's Dirac dispersion and a Schottky‐like back‐to‐back junction, the device achieves six‐orders‐of‐magnitude dark current suppression while retaining linearity over 200 V, enabling ...
Babar Shabbir, Shoaib Masood, Jialu Li, R. A. W. Ayyubi, Naeimeh Mozaffari, Mosarof Hossain, Nasir Mahmood, Muhammad Nadeem, Jacek J. Jasieniak   +8 more
wiley   +1 more source

An Integrated Oxygen‐Supplying Device and Predictive Multiphysics Model for Extended Ambient Transport of Insulin‐Producing Cells

Advanced Functional Materials, EarlyView.
Cell therapies typically rely on cold‐chain logistics and cryopreservation, limiting access and compromising cell quality. Here, a dual‐chamber device separates an oxygen‐supplying chamber from a hyaluronic acid cargo chamber, sustaining oxygen delivery for over 70 h and enabling ambient‐temperature shipment.
Daniel A. Domingo‐Lopez, Ruth Tarpey, Benjamin Brennan, Bryan D. Boyle, Amir M. Alsharabasy, Abhik Mallick, Gabriella Bellavia, Abhay Pandit, Garry P. Duffy, Ruth E. Levey   +9 more
wiley   +1 more source

Lactylation and Central Nervous System Diseases

Brain Sciences
As the final product of glycolysis, lactate serves as an energy substrate, metabolite, and signaling molecule in various diseases and mediates lactylation, an epigenetic modification that occurs under both physiological and pathological conditions ...
Ye Chen, Dongqiong Xiao, Xihong Li
doaj   +1 more source

Production of Butyrate from Lactate by a Newly Isolated Clostridium sp BPY5

, 2016
Lactate-utilizing bacteria play important roles in the production of Chinese strong-flavored liquor (CSFL). However, the identity of these bacteria and their lactate-utilizing properties are largely unknown.
Tang, QL, Tao, Y, Zhu, XY, Hu, XH, Jin, H, Xu, ZC, Li, XZ (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Key Lab Environm & Appl Microbiol, Environm Microbiol Key Lab Sichuan Prov, Chengdu 610041, Peoples R China., Li, XZ   +7 more
core   +1 more source

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

Advanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger, Min Jiang, Florian Belger, Fabian Link, Benjamin Winkeljann, Olivia M. Merkel   +5 more
wiley   +1 more source

Reliability of a non-invasive method to calculate buffer capacity after exhaustive cycling exercise of 20 s to 12 min: a pilot study

Frontiers in Sports and Active Living
Traditionally, buffer capacity (β) is measured on muscle biopsies by measuring changes in muscle pH in relation to exposure of standardized quantities of hydrochloric acid.
Sebastian Gehlert, Asatur Khurshudyan, Sebastian Weber, Jochem Widdershoven, Reinout Van Schuylenbergh, Reinout Van Schuylenbergh   +5 more
doaj   +1 more source

Use of an audio-paced incremental swimming test in young national-level swimmers [PDF]

, 2008
PURPOSE: To evaluate the reliability and sensitivity to training of an audio-paced incremental swimming test.METHODS: Eight young national-level male swimmers (age 15 +/- 1 year) performed a 7 x 200-m incremental swimming test (velocities 1.19, 1.24, 1 ...
Coleman, Simon G S, Smith, Taylor, Turner, Anthony P; id_orcid   +2 more
core  

Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

Advanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar, Laura Neely, Cynthia Pham, Nada Ibrahim, Alexis Larios‐Cervantes, Ben A. Kertesz, Todd Hoare   +6 more
wiley   +1 more source