Results 61 to 70 of about 553,288 (303)

Acute Effects of Two Different Concurrent Training Models on Physiological Parameters, Explosive Strenght and Balance Performance in Soccer Players

Türk Spor ve Egzersiz Dergisi
In the study, the acute effects of two different concurrent training models including high intensity interval training (HIIT) and high intensity interval functional training (HIFT) plus strength training (S) on physiological indicators (lactate and heart
Fatih Koçak, Salih Pinar, Birgül Arslan   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Whole blood ratio of CDK1/CX3CR1 mRNA expression combined to lactate refines the prediction of ICU mortality in septic patients in the Sepsis-3 era: a proof-of-concept study

Frontiers in Medicine
BackgroundTranscriptomics biomarkers have been widely used to predict mortality in patients with sepsis. However, the association between mRNA levels and outcomes shows substantial variability over the course of sepsis, limiting their predictive ...
Marie-Angélique Cazalis, Marie-Angélique Cazalis, Louis Kreitmann, Louis Kreitmann, Guillaume Monneret, Guillaume Monneret, Alexandre Pachot, Alexandre Pachot, Karen Brengel-Pesce, Karen Brengel-Pesce, Jean-François Llitjos, Jean-François Llitjos, Jean-François Llitjos   +12 more
doaj   +1 more source

Hypothermal Effects on Energy Supply for Ionocytes in Gills of Freshwater- and Seawater-Acclimated Milkfish, Chanos chanos

Frontiers in Marine Science, 2022
The milkfish, Chanos chanos, is an important aquaculture species that can be cultured in freshwater (FW) and seawater (SW) ponds because of its high euryhalinity. In winter, cold snap leading to high mortality of this tropical species is a critical issue
Chia-Hao Chang, Chia-Hao Chang, Chia-Jui Liu, Chia-Jui Liu, Wei-Jie Lu, Li-Yang Wu, Kuang-Jie Lai, Yu-Ting Lin, Yu-Ting Lin, Tsung-Han Lee, Tsung-Han Lee   +10 more
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

The influence of prenatal exercise modes on resting maternal blood lactate

Physiological Reports
Resting lactate concentration in venous blood is a commonly used indicator of metabolic disease risk. Regular exercise during pregnancy improves maternal metabolic health; however, it is unknown if maternal exercise regulates resting lactate ...
Alex Claiborne, Filip Jevtovic, Ericka M. Biagioni, Breanna Wisseman, Brittany Roenker, Kara Kern, Dylan Steen, Lindsey Rossa, Caitlyn Ollmann, Samantha Mcdonald, Cody Strom, Edward Newton, James Devente, Steven Mouro, David Collier, George A. Kelley, Jill Maples, Perrie O'Tierney‐Ginn, Nicholas T. Broskey, Joseph A. Houmard, Linda E. May   +20 more
doaj   +1 more source

Use of an audio-paced incremental swimming test in young national-level swimmers [PDF]

, 2008
PURPOSE: To evaluate the reliability and sensitivity to training of an audio-paced incremental swimming test.METHODS: Eight young national-level male swimmers (age 15 +/- 1 year) performed a 7 x 200-m incremental swimming test (velocities 1.19, 1.24, 1 ...
Coleman, Simon G S, Smith, Taylor, Turner, Anthony P; id_orcid   +2 more
core  

NMR-invisible lactate in blood plasma [PDF]

, 1988
Resonances for lactate are broadened in 500 MHz 1H NMR spectra of human blood plasma and only about one-third is visible in Hahn spin-echo spectra. Similar effects are observed for some other carboxylate anions.
Bell, Jimmy D., Sadler, P.J., Peter J. Sadler, Sadler, Peter J., Brown, J.C.C., Gina Kubal, Jimmy D. Bell, Kubal, G., Kubal, Gina, Bell, J.D., Brown, Judith C.C., Judith C.C. Brown   +11 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

The role of neutrophilia in hyperlactatemia, blood acidosis, impaired oxygen transport, and mortality outcome in critically ill COVID-19 patients

Frontiers in Molecular Biosciences
IntroductionCOVID-19 severity and high in-hospital mortality are often associated with severe hypoxemia, hyperlactatemia, and acidosis, yet the key players driving this association remain unclear.
Basma A. Yasseen, Aya A. Elkhodiry, Hajar El-sayed, Mona Zidan, Azza G. Kamel, Mohamed A. Badawy, Marwa S. Hamza, Riem M. El-Messiery, Mohamed El Ansary, Engy A. Abdel-Rahman, Engy A. Abdel-Rahman, Sameh S. Ali   +11 more
doaj   +1 more source