Results 41 to 50 of about 505,953 (316)

D-Lactate: Implications for Gastrointestinal Diseases [PDF]

open access: yes, 2023
D-lactate is produced in very low amounts in human tissues. However, certain bacteria in the human intestine produce D-lactate. In some gastrointestinal diseases, increased bacterial D-lactate production and uptake from the gut into the bloodstream take ...
Bahtiyar Yilmaz   +5 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Anesthetic Effects of Clove Basil Essential Oil (Ocimum gratissimum) Microemulsion on Asian Redtail Catfish (Hemibagrus wyckioides) and Its Biochemical Stress Indicators

open access: yesFishes
Ocimum gratissimum (clove basil) essential oil is known for its anesthetic and stress-reducing effects in aquatic animals. In this study, it was synthesized into a microemulsion form and its anesthetic effects on Hemibagrus wyckioides (Asian redtail ...
Phuong Hong Lam   +7 more
doaj   +1 more source

The Effect of Prehospital Fluid Resuscitation on Mortality and Post-trauma Recovery Time in Trauma Patients

open access: yesBagcilar Medical Bulletin, 2021
Objective:It was aimed to evaluate the effect of pre-hospital fluid resuscitation on serum lactate level, mortality, radiological imaging, and late post-trauma recovery (PRT) in patients with trauma, who were admitted to the emergency department.Method ...
Figen Tunalı Türkdoğan   +1 more
doaj   +1 more source

Role of mitochondrial lactate dehydrogenase and lactate oxidation in the intracellular lactate shuttle [PDF]

open access: yesProceedings of the National Academy of Sciences, 1999
To evaluate the potential role of mitochondrial lactate dehydrogenase (LDH) in tissue lactate clearance and oxidation in vivo , isolated rat liver, cardiac, and skeletal muscle mitochondria were incubated with lactate, pyruvate, glutamate, and succinate.
G A, Brooks   +4 more
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

A Wearable Electrochemical Biosensor for Lactate Monitoring in Sweat

open access: yes, 2023
This study aimed to optimize the inkjet printing process for the fabrication of rGO- based lactate biosensors. The ink used for printing possessed proper fluidic properties, and the droplets were connected on the film by repeated printing process.
Karim Hisham, Abdullah   +2 more
core   +1 more source

Foam Roller Post-High-Intensity Training for CrossFit Athletes: Does It Really Help with Recovery?

open access: yesJournal of Functional Morphology and Kinesiology
Background/Objectives: Foam rolling is a new and emergent recovery tool in sports. The aim of this study seeks to compare the acute effects of foam rolling and passive rest on recovery markers in CrossFit athletes following a high-intensity workout ...
Fernando Zarzosa-Alonso   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The effects of 5 days β-alanine supplementation on the velocity and the percentage o2max at the lactate threshold [PDF]

open access: yes, 2010
Purpose: To assess the effect of 5 days β-alanine supplementation on the velocity and the percentage of O2max ¬¬ (%O2max) at the lactate threshold (Tlac) during treadmill running.
Johnson, Matthew
core  

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