Results 31 to 40 of about 553,288 (303)

Molecular crowding defines a common origin for the Warburg effect in proliferating cells and the lactate threshold in muscle physiology [PDF]

, 2011
Aerobic glycolysis is a seemingly wasteful mode of ATP production that is seen both in rapidly proliferating mammalian cells and highly active contracting muscles, but whether there is a common origin for its presence in these widely different systems is
Vazquez, Alexei, Oltvai Zoltán N., Vazquez, A, Zoltán N Oltvai, Alexei Vazquez, Vazquez Alexei, Oltvai, ZN, Oltvai, Zoltán N., Zoltán N. Oltvai   +8 more
core   +2 more sources

CSF lactate dehydrogenase activity in patients with Creutzfeldt-Jakob disease exceeds that in other dementias [PDF]

, 2004
The diagnosis of Creutzfeldt- Jakob disease (CJD) is still made by exclusion of other dementias. We now evaluated lactate dehydrogenase (LDH) in the cerebrospinal fluid (CSF) as a possible additional diagnostic tool. CSF LDH levels of patients with CJD (
Cepek, L., Niedmann, P., Poser, S., Otto, M., Kretzschmar, Hans A., Otto, Markus, Poser, Sigrid, Schmidt, H., Schroter, A., Kretzschmar, H. A.   +9 more
core   +1 more source

Effect of site of lactate infusion on regional lactate exchange in pigs [PDF]

, 2010
BACKGROUND: The rate of extra-hepatic lactate production and the route of influx of lactate to the liver may influence both hepatic and extra-hepatic lactate exchange.
Barthelmes, Daniel; https://orcid.org/, Ahonen, H, Laitinen, S, Rahikainen, S, Takala, Jukka, S Rahikainen, S Laitinen, J Takala, S.M. Jakob, H Ahonen, Jakob, S M, Ahonen, Hanna-Mari, Takala, J, Barthelmes, D, D Barthelmes   +14 more
core   +2 more sources

Effect of mevalonate, zoledronate and BCG on monocyte/macrophage phenotype

Сибирский научный медицинский журнал, 2023
Cells of innate immunity, mainly monocytes/macrophages, form a long-term nonspecific immunological memory during the initial encounter with the pathogen, the so-called trained immunity.
A. P. Lykov, S. N. Belogorodtsev, E. K. Nemkova, A. Vetlugina, T. M. Terekhova, Ya. Sh. Schwartz   +5 more
doaj   +1 more source

Tetracycline and Lactation

The Journal of the American Dental Association, 1983
The Journal of the American Dental Association 107 (1983) 12,14-12,14.
UNIVERSITY OF FLORIDA, GAINESVILLE, FLAUNIVERSITY OF FLORIDAGAINESVILLEFLA ( host institution ), Hendeles, Leslie, Trask, Philip A.   +2 more
openaire   +3 more sources

Blood lactate clearance during active recovery after an intense running bout depends on the intensity of the active recovery [PDF]

, 2010
High-intensity exercise training contributes to the production and accumulation of blood lactate, which is cleared by active recovery. However, there is no commonly agreed intensity or mode for clearing accumulated blood lactate.
Kemi, O.J., John Wilson, Paterson, P., Laura McIntyre, McIntyre, L., Paul Paterson, Menzies, C., Paul Menzies, Ole J. Kemi, Menzies, P., Wilson, J., Craig Menzies   +11 more
core   +1 more source

Lactylation in tumor: mechanisms and therapeutic potentials

Frontiers in Immunology
Lactate, a central product of glucose metabolism, plays a vital role in energy supply and signal transduction, and it also participates in gene transcription regulation through lactylation.
Dandan Wang, Hao Rong, Ke Ma, Jun Peng
doaj   +1 more source

Potential source of bias in AI models: lactate measurement in the ICU in sepsis patients as a template

Frontiers in Medicine
ObjectiveHealth inequities may be driven by demographics such as sex, language proficiency, and race-ethnicity. These disparities may manifest through likelihood of testing, which in turn can bias artificial intelligence models.
Pratiksha Pradhan, Pratiksha Pradhan, Fredrik Willumsen Haug, Fredrik Willumsen Haug, Nebal S. Abu Hussein, Nebal S. Abu Hussein, Dana Moukheiber, Lama Moukheiber, Mira Moukheiber, Sulaiman Moukheiber, Luca Leon Weishaupt, Jacob G. Ellen, Helen D'Couto, Ishan C. Williams, Leo Anthony Celi, Leo Anthony Celi, Leo Anthony Celi, Joao Matos, Joao Matos, Joao Matos, Tristan Struja, Tristan Struja, Tristan Struja   +22 more
doaj   +1 more source

Lactate and lactylation in breast cancer: current understanding and therapeutic opportunities

Cancer Biology & Medicine
Breast cancer (BC) has the highest prevalence among cancers specific to women, and its incidence rates are increasing in many countries. Subtypes of BC, including HER2-positive or triple-negative BC, exhibit differing treatment responses; consequently ...
Lan Huang, Xuemei Chen, Meina Yan, Ze Xiang, Jian Wu   +4 more
doaj   +1 more source

Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis [PDF]

, 2005
Introduction: Acute metabolic acidosis of non-renal origin is usually a result of either lactic or ketoacidosis, both of which are associated with a high anion gap.
Treacher, David F, Forni, L.G., Forni, Lui G, William McKinnon, Gwyn A Lord, Hilton, Philip J, Peron, Jean-Marie R, McKinnon, W., McKinnon, William, Lord, Gwyn A, Hilton, P.J., Philip J Hilton, David F Treacher, Treacher, D.F., Lui G Forni, Lord, Gwyn A., Peron, J.M.R., Jean-Marie R Peron   +17 more
core   +1 more source