Results 111 to 120 of about 980,886 (403)

The place of D-dimer and L-lactate levels in the early diagnosis of acute mesenteric ischemia [PDF]

, 2015
INTRODUCTION: Acute mesenteric ischemia (AMI) is an abdominal-vascular emergency which is rare and has high mortality rates (60-80 %) due to late diagnosis (1-3).
Aydin, B., Aydin, C., Demirkan, Neşe Çallı, Kaptanoğlu, Bünyamin, Serinken, M., Özban, Murat   +5 more
core   +1 more source

Pivotal Roles for pH, Lactate, and Lactate-Utilizing Bacteria in the Stability of a Human Colonic Microbial Ecosystem

mSystems, 2020
Lactate is formed by many species of colonic bacteria, and can accumulate to high levels in the colons of inflammatory bowel disease subjects. Conversely, in healthy colons lactate is metabolized by lactate-utilizing species to the short-chain fatty ...
S. Wang, L. A. Rubio, S. Duncan, G. Donachie, G. Holtrop, Galiana Lo, F. Farquharson, J. Wagner, J. Parkhill, P. Louis, A. Walker, H. Flint   +11 more
semanticscholar   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Off-pump coronary bypass surgery adversely affects alveolar gas exchange [PDF]

, 2008
While the introduction of off-pump myocardial revascularization (OPCAB) has initially shown promise in reducing respiratory complications inherent to conventional coronary surgery, it has failed to eradicate them.
Biočina, Bojan, Gašparović, Hrvoje, Husedžinović, Ino, Jelić, Ivan, Nikić, Nada, Rudež, Igor, Sutlić, Željko, Unić, Daniel   +7 more
core   +1 more source

Lactate Regulates Metabolic and Proinflammatory Circuits in Control of T Cell Migration and Effector Functions [PDF]

, 2015
Licensed by the Creative Commons Attribution ...
A Ene-Obong, A Lardner, AM Sidahmed, C Croia, C Gobelet, C Mauro, C Nathan, CH Chang, Claudio Mauro, Costantino Pitzalis, DK Finlay, DR Wahl, DW Jung, Elliot J. Bland, F Humby, F Vegran, Federica M. Marelli-Berg, Fulvio D’Acquisto, FW Fitch, G Yi, J Olloquequi, J Zhu, Joanne Smith, JR Doherty, K De Bock, K Fischer, KJ Livak, LZ Shi, M Buzzai, M Chabaud, M Kleinewietfeld, M Sukumar, Mauro Perretti, ME Morris, Michele Bombardieri, MJ Ovens, MM Delmastro-Greenwood, N Shyh-Chang, O Haworth, OR Colegio, Philippa Marrack, PP Hsu, R Haas, R Wang, RA Robergs, RD Michalek, Robert Haas, S Su, SJ Jarmin, SN Mueller, SP Young, SR Srinivas, SS Metkar, Suchita Nadkarni, T Hashimoto, T Hitosugi, T Montero-Melendez, T Soga, TC Leite, Trinidad Montero-Melendez, VA Gerriets, Vidalba Rocher-Ros, Y Cao   +62 more
core   +5 more sources

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Lactate Dehydrogenases as Metabolic Links between Tumor and Stroma in the Tumor Microenvironment

Cancers, 2019
Cancer is a metabolic disease in which abnormally proliferating cancer cells rewire metabolic pathways in the tumor microenvironment (TME). Molecular reprogramming in the TME helps cancer cells to fulfill elevated metabolic demands for bioenergetics and ...
D. Mishra, D. Banerjee
semanticscholar   +1 more source

Functional parameters of spermatozoa obtained by a new selection device

FEBS Open Bio, EarlyView.
This study compares density gradient centrifugation and the LensHooke CA0™ device for sperm separation. DGC requires multiple steps, specialized equipment, and technical expertise. In contrast, the CA0 device offers key practical and methodological advantages, resulting in a faster, simpler, and more affordable sperm selection method.
Julio C. Chávez, Paulina Torres, Gabriela Carrasquel‐Martínez, María G. Figueroa‐Méndez, Diana Flores, Lina Villar, Israel Maldonado, Marcela B. Trevino, Claudia Treviño   +8 more
wiley   +1 more source

Oxygen consumption remains stable while ammonia excretion is reduced upon short time exposure to high salinity in Macrobrachium acanthurus (Caridae: Palaemonidae), a recent freshwater colonizer

Zoologia (Curitiba), 2017
Palaemonid shrimps occur in the tropical and temperate regions of South America and the Indo-Pacific, in brackish/freshwater habitats, and marine coastal areas.
Carolina A. Freire, Leonardo de P. Rios, Eloísa P. Giareta, Giovanna C. Castellano   +3 more
doaj   +1 more source

Using blubber explants to investigate adipose function in grey seals:glycolytic, lipolytic and gene expression responses to glucose and hydrocortisone [PDF]

, 2017
Adipose tissue is fundamental to energy balance, which underpins fitness and survival. Knowledge of adipose regulation in animals that undergo rapid fat deposition and mobilisation aids understanding of their energetic responses to rapid environmental ...
Bennett, Kimberley A., Hall, Ailsa J., Millward, Sebastian, Moss, Simon E. W., Robinson, Kelly J.   +4 more
core   +3 more sources