Results 181 to 190 of about 231,763 (293)

Allosteric regulation of L-lactate dehydrogenase: Beyond effector-mediated tetramerization. [PDF]

Protein Sci
Cai H, Shulami S, Štefanić Z, Hrenar T, Maršavelski A, Fishman A.   +5 more
europepmc   +1 more source

Autocrine fibroblast growth factor receptor 1 signaling activates lactate dehydrogenase A-aerobic glycolysis for human prostate cancer DU145 cell growth [PDF]

Xiaoming Xu, Tianqing Peng, Wang Li, Jiaren Pan, Huafeng Pan, Tingitng Gu, Zhongliang Cheng, Jian‐Ting Zhang   +7 more
openalex   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

Advanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu, Ruotong Li, Li Zhang, Hengli Lu, Binhui Yang, Qian Hu, Yining Tao, Haoran Mu, Jing Han, Pengfei Zan, Jiakang Shen, Dongqing Zuo, Hongsheng Wang, Wei Sun, Xingjun Zhu   +14 more
wiley   +1 more source

Shotgun metagenomic mining reveals a new FAD-dependent D-lactate dehydrogenase in an isopod gut microbiome. [PDF]

Appl Environ Microbiol
Coelho C, Taborda A, Lorena C, Frazão T, Veríssimo A, Borges PT, Brissos V, Tiago I, Martins LO.   +8 more
europepmc   +1 more source

Does brain radiotherapy and lactate dehydrogenase (LDH) levels affect the prognosis of melanoma with brain metastases? [PDF]

Huishan Zhang, Li Zhu, Zhongqiao Lin, Lei Shi, Zequn Sun, Yu Chen, Jing Lin   +6 more
openalex   +1 more source

Disrupting CSPG‐Driven Microglia–Astrocyte Crosstalk Enables Scar‐Free Repair in Spinal Cord Injury

Advanced Science, EarlyView.
This study identifies CSPGs as key drivers of glial scar maturation after spinal cord injury by reprogramming microglial metabolism and inducing astrocyte fibrosis. To address this, a reactive oxygen species‐responsive, reactive astrocyte‐targeted ChABC gene delivery system is designed to locally degrade CSPGs, precisely disrupt maladaptive glial ...
Yufei Zheng, Zhaowei Zhang, Zezhou Fu, Qingqing Wang, Siwen Zhang, Tingyu Zhang, Meifei Zhu, Shunwu Fan, Youqing Shen, Jiajia Xiang, Xin Liu   +10 more
wiley   +1 more source

Serum lactate Dehydrogenase-to-Albumin ratio in upper tract urothelial carcinoma: A promising prognostic biomarker. [PDF]

BMC Urol
Wang Q, Zheng L, Ye J, Liao X, Chen Z, Wang X, Zhang C, Wei Q, Bao Y.   +8 more
europepmc   +1 more source

Effects of phospholipids on L-lactate dehydrogenase from membranes of Escherichia coli. Activation and stabilization of the enzyme with phospholipids

, 1978
Hironobu Kimura, Masamitsu Futai
openalex   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

Advanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr   +14 more
wiley   +1 more source

Lactate dehydrogenase to albumin ratio as a prognostic indicator for patients with resectable non-small cell lung cancer. [PDF]

Ann Med Surg (Lond)
Wei B, Li W, Qian K, Zhang P, Li Y, Shi K, Zhang Y.   +6 more
europepmc   +1 more source