Results 191 to 200 of about 785,757 (422)
Pulmonologists-Level lung cancer detection based on standard blood test results and smoking status using an explainable machine learning approach [PDF]
arXivLung cancer (LC) remains the primary cause of cancer-related mortality, largely due to late-stage diagnoses. Effective strategies for early detection are therefore of paramount importance. In recent years, machine learning (ML) has demonstrated considerable potential in healthcare by facilitating the detection of various diseases. In this retrospective
arxiv
Fermenting Seizures with Lactate Dehydrogenase [PDF]
Epilepsy Currents, 2015 Manisha Patel, Lindsey B. Gano
openaire +3 more sources
Advanced Science, EarlyView.IR783‐stabilized nanodrugs composed of NIR dye IR783, ROS inducer β‐lapachone, and epigenetic modulator CUDC101 are designed for breast cancer immunotherapy. The nanodrugs can not only promote cancer cell apoptosis through HDAC inhibition‐enhanced oxidation therapy but also reshape the immunosuppressive microenvironment, which provides a novel strategy
Jinzhao Liu +6 more
wiley +1 more source
A mathematical study of the interaction between oxygen and lactate in an in-vivo and in-vitro tumor [PDF]
arXivMicro-environmental acidity is a common feature of the tumor. One of the causes behind tumor acidity is lactate production by hypoxic cells of the tumor. Hypoxia is a direct result of the establishment of oxygen gradients. It is commonly observed in the tumor in an in-vitro experimental setup and also in-vivo situation.
arxiv
A zinc-dependent lactate dehydrogenase in Euglena gracilis [PDF]
, 1962 C. R. Price
openalex +1 more source
Advanced Science, EarlyView.The splicing factor PTBP3 promotes COX11 exon skipping, allowing gastric cancer organoids to evade cuproptosis. Antisense oligonucleotide drugs targeting PTBP3‐mediated COX11 alternative splicing, in combination with copper ionophores, promote cuproptosis in organoids, thereby providing a therapeutic approach for gastric cancer peritoneal metastasis ...
Yajing Zhou +11 more
wiley +1 more source
Effect of Denervation on the Lactate Dehydrogenase Isozymes of Skeletal Muscle [PDF]
, 1965 Irwin A. Brody
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Effect of hyperbaric oxygenation on carbohydrate metabolism protein synthesis in the myocardium during sustained hypodynamia [PDF]
Glycolysis and the intensity of protein synthesis were studied in 140 white male rats in subcellular fractions of the myocardium during 45 day hypodynamia and hyperbaric oxygenation.
Makarov, G. A.
core +1 more source
Global Metabolic Shifts in Age and Alzheimer's Disease Mouse Brains Pivot at NAD+/NADH Redox Sites. [PDF]
, 2019 Age and Alzheimer's disease (AD) share some common features such as cognitive impairments, memory loss, metabolic disturbances, bioenergetic deficits, and inflammation.
Brewer, Gregory J, Dong, Yue
core