Results 211 to 220 of about 231,763 (293)
Lactate dehydrogenase A: a potential new target for tumor drug resistance intervention. [PDF]
Wang M +6 more
europepmc +1 more source
Bacterial biofilms form a physicochemical barrier. Their dense network structure and redox homeostasis confer high resistance to antimicrobial treatments and immune‐mediated killing and clearance. In this study, SnSe nanosheets with enzyme‐like properties and piezoelectric catalysis can oscillate to regulate bacterial redox homeostasis and improve the ...
Min Ge +9 more
wiley +1 more source
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang +10 more
wiley +1 more source
Prognostic value of the lactate dehydrogenase-to-albumin ratio for predicting mortality in critically ill pediatric patients: a retrospective cohort study. [PDF]
Liu M, Gou Y, Yang P.
europepmc +1 more source
This study demonstrates a cuproptosis mechanism involving nicotinamide adenine dinucleotide (NADH)‐reductive stress in neural cells. Copper activates dihydrolipoamide dehydrogenase under mitochondrial pH, accumulating NADH. Copper also induces mitochondrial permeability transition pore opening, facilitating NADH translocation to the cytosol and ...
Si‐Yi Zhang +3 more
wiley +1 more source
Lactate dehydrogenase (LDH) Activity in retinoblastoma
Rohatgi A, Singh R, Shukla P
doaj
A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu +15 more
wiley +1 more source
Temperature adaptation in structure and function in lactate dehydrogenase-A reflects convergent evolution in a few key protein regions. [PDF]
Zhu XL +4 more
europepmc +1 more source

