Results 81 to 90 of about 81,911 (253)

A Comparison Of Wearable Lactate Threshold Technology To Accepted Methods Of Lactate Threshold Determination

Medicine & Science in Sports & Exercise, 2021
Lindsay Parisi, Jessica Alsup, Brittany Benoit, Danielle Patton, Brianna DiMattia   +4 more
openaire   +2 more sources

Sweat lactate sensor for detecting anaerobic threshold in heart failure: a prospective clinical trial (LacS-001)

Scientific Reports
A simple method for determining the anaerobic threshold in patients with heart failure (HF) is needed. This prospective clinical trial (LacS-001) aimed to investigate the safety of a sweat lactate-monitoring sensor and the correlation between lactate ...
Yoshinori Katsumata, Yuki Muramoto, Noriyuki Ishida, Ryo Takemura, Kengo Nagashima, Takenori Ikoma, Naoto Kawamatsu, Masaru Araki, Ayumi Goda, Hiroki Okawara, Tomonori Sawada, Yumiko Kawakubo Ichihara, Osamu Hattori, Koki Yamaoka, Yuta Seki, Toshinobu Ryuzaki, Hidehiko Ikura, Daisuke Nakashima, Takeo Nagura, Masaya Nakamura, Kazuki Sato, Yasuyuki Shiraishi   +21 more
doaj   +1 more source

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

Advanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang, Shengxin Lu, Guangyong Zheng, Shensuo Li, Hongyu Chen, Mei Hong, Xiangru Zhou, Ruotian Tang, Ye Wu, Weidong Zhang, Dong Lu, Xin Luan   +11 more
wiley   +1 more source

Physiological Key Determinants of Elite Open-Water Swimmers

Physiologia
This study describes the relationships between different physiological measurements and combinations of critical velocity and performance in elite open-water swimmers. A total of 15 international male open-water swimmers performed a 5 × 200 m front crawl
Robin Pla, Yannis Raineteau, Xavier Barbier, Anaël Aubry   +3 more
doaj   +1 more source

Triple‐Negative Breast Cancer Cells Utilize IL8 and CXCL1 to Suppress NK Cells’ Function and Facilitate Cancer Metastasis

Advanced Science, EarlyView.
Triple‐negative breast cancer (TNBC) cells evade natural killer (NK) cell immunity by secreting IL8 and CXCL1. These chemokines suppress NK cells’ function via CXCR1/2 and enhance cancer cells’ survival through PD‐L1 upregulation and BCL‐2 anti‐apoptotic signaling.
Mingheng Yuan, Hongmei Yang, Renfei Wu, Meng Hao, Xiangpeng Chu, Chuxia Deng, Kathy Qian Luo   +6 more
wiley   +1 more source

Agreement between heart rate variability‐derived and lactate/ventilatory thresholds during a 4‐min stepwise incremental cycling test in male adults

Physiological Reports
Accurate exercise intensity thresholds are key for endurance training prescription. The non‐linear heart rate (HR) variability (HRV) index DFAa1 has been proposed as a threshold determination marker, with DFAa1 values of 0.75 (HRVT1) and 0.5 (HRVT2 ...
Anton Olieslagers, Yoram Müller‐Jabusch, Margot Vancoillie, Emma Delen, Toon de Beukelaar   +4 more
doaj   +1 more source

Lactoferrin Deficiency During Lactation Causes Adult Obesity‐Related Metabolic Disease Through Persistent Adipose Dysfunction Driven by Impaired Adipocyte Development

Advanced Science, EarlyView.
Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An, Yunxia Zou, Wenli Wang, Zhimei Cheng, Zhuoxing Zhang, Ruwei Liu, Xiong Wang, Kunlun Huang, Fangrong Ding, Yunping Dai, Qingyong Meng, Yali Zhang   +11 more
wiley   +1 more source

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

Advanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

ZDHHC17‐Mediated CDK4 Palmitoylation Drives Cell Cycle Progression and Orchestrates Cancer Immune Surveillance

Advanced Science, EarlyView.
ZDHHC17 palmitoylates CDK4, which together with TRAF6‐mediated ubiquitination, drives cell cycle progression and immune surveillance, revealing a rational combination of CDK4 inhibitors with immune checkpoint blockers for ZDHHC17‐driven cancers. ABSTRACT Uncontrolled cell cycle progression is a hallmark of cancer, tightly regulated by both intrinsic ...
Zekang Wang, Peipei Song, Xueji Wu, Lei Wang, Wei Xie, Pinning Feng, Chao Cheng, Jianping Guo   +7 more
wiley   +1 more source

Stride-to-stride variability and fluctuations at intensities around lactate threshold in distance runners. [PDF]

Heliyon, 2023
Watanabe T, Kondo S, Kakinoki K, Fukusaki C, Hatta H.   +4 more
europepmc   +1 more source