Results 51 to 60 of about 21,122 (246)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Studies on some factors influencing the shape of the lactation curve in Romanian Black and White cows

Scientific Papers Animal Science and Biotechnologies, 2023
The aim of this paper was to study the effects of farm and parity on the shape of the lactation curve for milk yield, milk fat percentage, milk protein percentage and milk lactose percentage.
Traian Cismaș, Ludovic-Toma Cziszter, Stelian Acatincăi, Simona Baul, Silvia Erina, Dinu Gavojdian   +5 more
doaj  

Omission of dry period and effects on the subsequent lactation curve and on milk quality around calving in Italian Holstein cows

Italian Journal of Animal Science, 2010
The aim of this study was to investigate the effect of dry period omission on subsequent milk production over a whole lactation and the effect on milk quality around calving.
Giovanni Bittante, Gianfranco Gabai, Lucia Bailoni, Lieta Marinelli, Roberto Mantovani   +4 more
doaj   +1 more source

Evaluation of Different Test-Day Milk Recording Protocols by Wood’s Model Application for the Estimation of Dairy Goat Milk and Milk Constituent Yield

Animals, 2021
Goats have important social and economic roles in many countries because of their ability to survive and be productive in marginal areas. The overarching aim of this study was to compare the application of Wood’s model to different test-day milk ...
Vincenzo Landi, Aristide Maggiolino, Angela Salzano, Salvatore Claps, Pasquale De Palo, Domenico Rufrano, Giuseppina Pedota, Gianluca Neglia   +7 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Use of Spline function for the characterisation on peak yield, peak day and persistency in lactation curves in Murciano-Granadina goats

Italian Journal of Animal Science, 2019
The objective of this study was to characterise the peak yield (PY), peak day (PD) and the persistency (P) of the lactation curve of Murciano-Granadina goats by Spline considering the variation factors (region, type of kidding, lactation number and ...
Judith Carmen Miranda-Alejo, José Manuel León-Jurado, Camillo Pieramati, Mayra Mercedes Gómez Carpio, Jesús Valdés-Hernández, Cecilio José Barba-Capote   +5 more
doaj   +1 more source

Comparison of the parameters of the lactation curve between normal and difficult calvings in Iranian Holstein cows

Spanish Journal of Agricultural Research, 2019
To evaluate effect of dystocia on the lactation curve characteristics for milk yield and composition in Holstein cows, six non-linear models (Brody, Wood, Sikka, Nelder, Dijkstra and Rook) were fitted on 5,917,677 test day records for milk yield (MY ...
Navid Ghavi Hossein-Zadeh
doaj   +1 more source