Results 51 to 60 of about 44,362 (300)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Antidepressants in pregnancy and breastfeeding [PDF]

, 2007
Copyright © 2007 Australian Prescriber Reproduced with permission from Australian Prescriber The document attached has been archived with permission from the publisher/copyright holder.Maternal depression and anxiety during pregnancy and the early years ...
Anna Sved Williams, Sved-Williams, A.
core   +1 more source

Estimation of Dairy Cow Survival in the First Three Lactations for Different Culling Reasons Using the Kaplan–Meier Method

Animals, 2022
The aims of the study were: (i) to compare survival curves for cows culled for different reasons over three successive lactations using the Kaplan–Meier estimator; (ii) to determine the effects of breeding documentation parameters on cow survival; (iii ...
Wilhelm Grzesiak, Krzysztof Adamczyk, Daniel Zaborski, Jerzy Wójcik   +3 more
doaj   +1 more source

Diagnostic Value of Lactate Levels in Acute Abdomen Disorders [PDF]

Indian Journal of Clinical Biochemistry, 2013
The supply of oxygen is limited in certain intra abdominal conditions due to direct vascular invasion or inflammatory process, resulting in high lactate levels. Aim of this study was to find the predictive value of lactate levels in the peritoneal fluid (PF) and blood of patients with acute abdomen.
Indu, Verma, Satinder, Kaur, Subash, Goyal, Shweta, Goyal, J S, Multani, A P S, Narang   +5 more
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Factors related to unsuccessful lactogenesis – a literature review

Online Brazilian Journal of Nursing, 2009
<p class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: 150%;"><span style="font-family: Arial; mso-ansi-language: EN-US;"><span style="font-size: x-small;">The objective of this literature review was to investigate the factors ...
Natália de Godoy Ferro, Ianê Nogueira do Vale, Elenice Valentim Carmona, Ana Cristina Freitas de Vilhena Abrão   +3 more
doaj  

DIFICULDADES INICIAIS COM A TÉCNICA DA AMAMENTAÇÃO E FATORES ASSOCIADOS A PROBLEMAS COM A MAMA EM PUÉRPERAS

Revista Paulista de Pediatria
RESUMO Objetivo: Identificar a prevalência de condições indicativas de dificuldades iniciais com a técnica da amamentação e verificar os fatores associados com a presença de problemas na mama em puérperaso em maternidades de Hospitais Amigos da Criança.
Gessandro Elpídio Fernandes Barbosa, Victor Bruno da Silva, Janeide Mendes Pereira, Marianne Silva Soares, Rosemberg dos Anjos Medeiros Filho, Luciana Barbosa Pereira, Lucinéia de Pinho, Antônio Prates Caldeira   +7 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Metabolic adaptation recorded during one lactation does not allow predicting longevity in dairy cows.

, 2016
INTRODUCTION Metabolic and health disorders account distinctly for culling in dairy cows. This study investigated if metabolic status obtained once in life during a negative energy balance in early lactation allows to predict age and lifetime ...
Bruckmaier, Rupert, Grossen-Rösti, Linda, Schmitz-Hsu, F, Gross, Josef Johann   +3 more
core   +1 more source

Association between body energy content in the dry period and post-calving production disease status in dairy cattle

Animal, 2017
The transition from gestation to lactation is marked by significant physiological changes for the individual cow such that disease incidence is highest in early lactation.
G.L. Smith, N.C. Friggens, C.J. Ashworth, M.G.G. Chagunda   +3 more
doaj   +1 more source