Results 61 to 70 of about 122,904 (360)

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Genetic variation in dairy cattle claw health traits recorded by claw trimmers [PDF]

open access: yes, 2013
Claw health has been recorded by claw trimmers at trimming in Sweden since 1996, but data was then captured at each AI association. From 2003 data was captured by central scanning and entered directly to the national cow data base at the Swedish Dairy ...
Naeslund, Sandra
core   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

Patients’ perception of childbirth according to the delivery method: The experience in our clinic [PDF]

open access: yes, 2019
Introduction: The aim of this study is to identify the way in which childbirth in general, and the delivery method in particular, influenced the maternal psychosocial status and the perception upon birth during postpartum.
Alexandroaia, Camelia   +4 more
core   +3 more sources

Quantitative constraint-based computational model of tumor-to-stroma coupling via lactate shuttle [PDF]

open access: yesScientific Reports 5, 11880 (2015), 2015
Cancer cells utilize large amounts of ATP to sustain growth, relying primarily on non-oxidative, fermentative pathways for its production. In many types of cancers this leads, even in the presence of oxygen, to the secretion of carbon equivalents (usually in the form of lactate) in the cell's surroundings, a feature known as the Warburg effect.
arxiv   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Severity of experimental escherichia-coli mastitis in ketonemic and nonketonemic dairy-cows. [PDF]

open access: yes, 1993
The severity of experimental Escherichia coli mastitis in relation to in vitro chemotaxis of polymorphonuclear leukocytes was investigated in cows during negative energy balance. The negative energy balance was induced by feed restriction.
Brand, A   +6 more
core   +1 more source

Abortion Effects on Production, Reproductive Performance, and Health of Dairy Cattle

open access: yesActa Veterinaria Eurasia
In order to investigate the consequences of abortions on dairy cattle performance, records from the software of seven dairy farms in Argentina were studied between February 2015 and June 2019.
Víctor Humberto SUAREZ   +2 more
doaj   +1 more source

Non-additive QTL mapping of lactation traits in 124,000 cattle reveals novel recessive loci

open access: yesGenetics Selection Evolution, 2022
Background Deleterious recessive conditions have been primarily studied in the context of Mendelian diseases. Recently, several deleterious recessive mutations with large effects were discovered via non-additive genome-wide association studies (GWAS) of ...
Edwardo G. M. Reynolds   +14 more
doaj   +1 more source

Diagnosis and Therapy of Psychosomatic Disorders in Reproductive Cycle of Women in General Medical Practice (Review)

open access: yesАрхивъ внутренней медицины, 2022
The incidence of different psychiatric disorders (affective, anxious, dysmorphic, psychotic) during menstruation, pregnancy and the postpartum period reaches 80 %.
V. E. Medvedev
doaj   +1 more source

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