Results 111 to 120 of about 2,048,354 (300)

Cisternal milk in the dairy cow during lactation and after preceding teat stimulation [PDF]

open access: yes, 1996
Experiments were designed to determine the cisternal milk during machine milking in unfamiliar surroundings, which has previously been shown to inhibit milking-related oxytocin (OT) release and milk ejection.
Bruckmaier, Rupert M.   +8 more
core   +2 more sources

Mechanism‐Informed Language Modeling and Oxygenated 3D Screening Identify Berberine–Enzalutamide Synergy in Prostate Cancer Models

open access: yesAdvanced Science, EarlyView.
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo   +15 more
wiley   +1 more source

The Association of Delayed Milk Ejection and Milk Production in Dairy Cows Milked by an Automated Milking System

open access: yesAnimals
This retrospective cohort study examined the association between delayed milk ejection (DME), defined as bimodal milk flow, and milk yield in dairy cows milked with an automated milking system (AMS).
Matthias Wieland, Heleen ten Have
doaj   +1 more source

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

open access: yesAdvanced Science, EarlyView.
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang   +12 more
wiley   +1 more source

The influence of environmental factors on daily milk yield and fat and protein content in Istrian sheep

open access: yesMljekarstvo, 2012
The objective of this study was to analyse the effect of stage of lactation, parity, litter size, and lambing season on daily milk production and fat and protein content in Istrian sheep.
Marija Špehar   +4 more
doaj  

A Novel Reactive Oxygen Species‐Responsive Bone‐Targeted Nanoplatform Based on Cloperastine Attenuates Ovariectomy‐Induced Bone Loss by Inhibiting Osteoclast Oxidative Phosphorylation

open access: yesAdvanced Science, EarlyView.
Cloperastine suppresses osteoclastogenesis by inhibiting PGC1β‐mediated oxidative phosphorylation. Its incorporation into a ROS‐responsive, Asp8‐modified nanoplatform enhances skeletal accumulation. The resulting Clo/Asp8‐PMK‐MCs combine cloperastine‐mediated antiresorptive activity with carrier‐mediated osteogenic activity to attenuate OVX‐induced ...
Haibo Liang   +16 more
wiley   +1 more source

Effect of Milking Frequency and Pasture Intake on Milk Yield and Composition of Late Lactation Cows

open access: yesJournal of Dairy Science, 1999
Twenty-four monozygous twinsets in late lactation (> 210 d in milk) were used to examine the effects of feed restriction and milking frequency prior to drying off on milk yield and composition in a pastoral dairying system. Cows were assigned to one of four treatment groups for 26 d and were milked either twice or once daily and given either ...
S J, Lacy-Hulbert   +4 more
openaire   +2 more sources

A Biomimetic cRGDyk‐Engineered Platelet Nanoplatform for ACAD11 Delivery to Trigger Pyroptosis in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
A biomimetic platelet nanoplatform (OE‐ACAD11@R‐PLT) is developed for targeted hepatocellular carcinoma immunotherapy. By selectively delivering therapeutic plasmids, this system induces mitochondrial dysfunction and triggers robust NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis in tumor cells.
Hongyi Bao   +12 more
wiley   +1 more source

Genetic and phenotypic parameters of lactations longer than 305 days (extended lactations)

open access: yesAnimal, 2008
Test-day milk yield and somatic cell count data over extended lactation (lactation to 540–600 days) were analysed considering part lactations as different traits and fitting random regression (RR) models.
M. Haile-Mariam, M.E. Goddard
doaj   +1 more source

Rearing conditions and lifetime milk revenues in Swedish dairy cows [PDF]

open access: yes, 2011
Associations between replacement heifer rearing conditions and lifetime milk revenues were studied throughout the productive life of Swedish dairy cows.
Svensson, Catarina,   +8 more
core   +1 more source

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