Results 51 to 60 of about 2,048,354 (300)

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu, Xi Yu, Tao Wang, Wanyi Liu, Chang Lu, Jiani Zhong, Yujie He, Wei Li, Kunxi Zhang, Peihao Yin, Zeting Yuan   +10 more
wiley   +1 more source

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

Estimates of correction factors for lactation length and genetic parameters for milk yield in buffaloes [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2004
Correction factors for milk yield at 90, 240, 270 and 305 days of lactation of buffaloes and genetic and environmental parameters for milk yield of these lactation periods were estimated.
H. Tonhati, M.F.C. Muñoz, J.M.C. Duarte, R.H. Reichert, J.A. Oliveira, A.L.F. Lima   +5 more
doaj   +1 more source

AARS1‐Mediated H3K27 Lactylation Rewires Glycolysis to Sustain Aggressive and Recurrent Bladder Cancer

Advanced Science, EarlyView.
AARS1 drives PI3K–AKT–mTOR‐dependent glycolysis in bladder cancer, promoting lactate accumulation, increased lactylation, H3K27la enrichment at the HK2 promoter, and HK2 transcription. HK2 reinforces glycolysis, sustaining a metabolic–epigenetic program associated with tumor progression, recurrence, and metastasis.
Qin Yuan, Tianbao Song, Yipeng He, Sihan Xia, Yaoqiu Huang, Wenlin He, Qin Yi, Zefeng Wang, Peihan Wang, Chenbo Huang, Linzhi Li, Zhen Yin, Fan Cheng, Weimin Yu   +13 more
wiley   +1 more source

Environmental factors on the prediction of the lactation curve of Holstein cows [PDF]

Pesquisa Agropecuária Brasileira
The objective of this work was to evaluate the influence of environmental factors on the lactation curve parameters and milk yield of Holstein cows. Data on lactations conducted from 2010 to 2019 in the state of Paraná, Brazil, obtained from the official
Amauri Felipe Evangelista, Rafaela Martins, Altair Antônio Valotto, Laila Talarico Dias, Rodrigo de Almeida Teixeira   +4 more
doaj   +1 more source

STUDIES ON FRIESIAN CATTLE IN EGYPT 2- GENETIC FACTORS AFFECTING MILK PRODUCTION [PDF]

Journal of Animal and Poultry Production, 2000
The same previous milk records used in studying the environmental factors affecting milk production (total of 1797 records of 765 cows) were used to study the genetic factors, repeatability , heritability and sire transmitting ability .
K. Hussein, M. Abdel-Glil, A. El-barbary, F. Farrag,   +3 more
doaj   +1 more source

Productive and reproductive performance of Siri cattle under field condition in West Bengal

Indian Journal of Animal Sciences, 2021
A study was undertaken with an objective to assess productive and reproductive performance of Siri cattle in West Bengal. The study was conducted among 80 farmers rearing either Siri-Pure or Siri-Graded cattle in the hilly region.
RAKESH ROY, RUPASI TIWARI, TRIVENI DUTT
doaj   +1 more source

Mammary Growth During Lactation: Implications for Increasing Milk Yield

Journal of Dairy Science, 1987
Milk yield is greatly influenced by the size of the mammary secretory cell population. In rats, proliferation of cells during early lactation may account for as much as three-quarters of the increase in daily milk yield between parturition and peak lactation; the remainder is due to increased activity of existing cells.
C H, Knight, C J, Wilde
openaire   +2 more sources

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Characteristics of milk production traits of Balkan goats raised under “low-input” production systems

Mljekarstvo, 2010
In order to analyse dairy production traits (milk yield in full lactation, milk fat content, daily milk yield and length of lactation) of Balkan goats raised under “low-input” production systems, data on 440 lactation records from 118 does raised on 9 ...
Vladan Bogdanović
doaj