Results 81 to 90 of about 2,048,354 (300)

Lactylation‐Driven PROS1‐TYRO3‐CARF Signaling Promotes Therapy‐Induced Senescence Escape and Radioresistance in Meningioma

Advanced Science, EarlyView.
A glycolysis‐driven epigenetic switch promotes therapy resistance in meningioma. Increased lactate production enhances histone H3K27 lactylation, which activates PROS1 secretion. Secreted PROS1 engages TYRO3 signaling to degrade the senescence regulator CARF, allowing cancer cells to escape growth arrest.
Zhuohang Wang, Qixiang Zhang, Keman Liao, Xiaoyu Liu, Hongchi Zhang, Yunsheng Chen, Yuxiao Ma, Yikui Liu, Aoqian Xu, Yuhao Sun, Jiayi Chen, Liuguan Bian, Baofeng Wang   +12 more
wiley   +1 more source

Bias and Accuracy of Single Milking Testing Schemes to Estimate Daily and Lactation Milk Yield

Journal of Dairy Science, 1995
This study evaluated the adequacy of an alternate a.m.-p.m. testing scheme for milk yield in comparison with the official test method based on weighing two milkings within 24 h. A total of 88,558 single test day milking weights from 15,670 Italian Friesian cows in 610 herds in the province of Milano (Italy) were collected between September 1991 and ...
CASSANDRO, MARTINO, CARNIER, PAOLO, GALLO, LUIGI, MANTOVANI, ROBERTO, CONTIERO, BARBARA, BITTANTE, GIOVANNI, JANSEN GB   +6 more
openaire   +2 more sources

Hot Topic: Effects of Frequent Milking in Early Lactation on Milk Yield and Udder Health [PDF]

Journal of Dairy Science, 2004
A field study was conducted to evaluate the influence of milking frequency (3 or 6 times/d [3x or 6x, respectively]) during the initial 21 d of lactation on milk and milk component yield and mammary gland health as indicated by somatic cell count. During 2 seasons, spring and fall, multiparous cows were milked 6 times/d until d 21 of lactation and then
G E, Dahl, R L, Wallace, R D, Shanks, D, Lueking   +3 more
openaire   +2 more sources

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

Advanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong, Chaochao Luo, Zezheng Liu, Xinyan Zhang, Daixu Jia, Yang Sun, Zhaonan Zhang, Haoran Shi, Jianfang Wang, Hua Zhang   +9 more
wiley   +1 more source

Effects of calf sex, breed and parity on the lactation performance of dairy cows in Trinidad and Tobago

Discover Agriculture
Dairy farming is important for food and nutrition security and livelihood protection in most tropical countries. However, productivity of dairy cows is affected by many factors and is usually low on smallholder farms in tropical environments.
Erica Auguste, Martin Hughes, Sivakumar Karuppusamy   +2 more
doaj   +1 more source

ANALYSIS OF THE RELATIONSHIP BETWEEN FIRST THREE LACTATIONS OF HOLSTEIN COWS [PDF]

Poljoprivreda, 2005
The objective of this study was to evaluate relationship between milk yield in the first three lactations regarding levels of milk yield in the first lactation and levels of age at the first calving.
Vesna Gantner, Sonja Jovanovac, K. Kuterovac   +2 more
doaj  

The effect of stage of lactation on daily milk yield, and milk fat and protein content in Tsigai and Improved Valachian ewes

Mljekarstvo, 2015
The objective of this study was to analyse the effect of stage of lactation on daily milk yield, and milk fat and protein content in Tsigai and Improved Valachian ewes.
Marta Oravcová, Milan Margetín, Vladimír Tančin   +2 more
doaj   +1 more source

Effects of pregnancy on daily milk yield of Holstein-Friesian dairy cattle

, 2004
First, second and third lactation curves of 21,885 first lactation dairy cows were allowed to vary depending on the months in milk at which the cow became pregnant. The curves were modelled using a 4th degree polynomial of days in milk. In the models for
Brotherstone, S., White, I. M. S., Thompson, R., Thompson, Robin   +3 more
core   +1 more source

Asymmetric Structure‐Driven Functional Synergy: A Multistimuli‐Activated Janus Nanomotor for Self‐Amplifying NO Cascade Therapy

Advanced Science, EarlyView.
The Janus nanomotors leverage an “asymmetric structure‐driven functional synergy” strategy to orchestrate spatiotemporally coordinated catalytic functions, in situ self‐amplifying NO generation, and deep tumor penetration, thereby enabling controllable, sustained, and uniform NO generation within the tumor microenvironment.
Chengcheng Li, Yu Zhang, Yu Chen, Lingyun He, Xian Shen, Weijian Sun, Hongbo Zhang   +6 more
wiley   +1 more source

Performance evaluation and prediction of first lactation milk yield in Vrindavani cattle

Indian Journal of Animal Sciences, 2019
The present investigation was carried out using first lactation milk records of 1,084 Vrindavani cows spread over a period of 17 years (2000–2017). The overall performance, effect of non-genetic factors on the first lactation test day (TD) milk yields,
JHARNA CHANDRAKAR, AMIT KUMAR, S NASKAR, G K GAUR, TRIVENI DUTT   +4 more
doaj   +1 more source