Results 41 to 50 of about 36,384 (260)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Lactational Performance of Various Mammalian Species

Journal of Dairy Science, 1986
Lactational performance varies widely among mammalian species. Lactation plays a variable role in the overall reproductive strategy. The fraction of total growth and development of the young contributed by lactation is minimal in such species as guinea pigs but is a very high proportion in some marsupials and primates.
openaire   +2 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Impact of multi-enzyme supplementation on sow reproductive performance, apparent nutrient digestibility, and lactation performance

South African Journal of Animal Science
This study evaluated the effects of supplementing a reduced-energy diet with a compound enzyme on sow performance, nutrient utilisation, and faecal characteristics.
Guanglei Cong, Chunxue Liu, Shuangshuang Xia, Junbo Li, Ifen Hung   +4 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

High-dose phytosterols supplementation improves lactation performance, modulates rumen microbiota, and reduces methane emission intensity in mid-lactation Holstein dairy cows [PDF]

Veterinary World
Background and Aim: Enteric methane emission from dairy cows contributes substantially to greenhouse gas production and represents an inefficient loss of dietary energy.
Dong Li, Yinyin Kyawt, Qi Wang, Jian Gao, Rong Wang, Min Wang, Chen Duan, Donghai Lv, Weiyun Zhu, Metha Wanapat, Yanfen Cheng   +10 more
doaj   +1 more source

Effects of lameness at the time of drying off on the lactation and fertility performance of the following lactation [PDF]

Schweiz Arch Tierheilkd, 2018
The aim of the study was to clarify how lameness and its severity in dairy cows at the time of drying off will affect the milk performance and fertility in the following lactation when treated appropriately at the time of drying off. The lameness scoring and a gait assessment took place during drying off, in the 1st week after calving, as well as 2 ...
M, Hässig, C, Degen Aguayo Aparicio, K, Nuss   +2 more
openaire   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Effects of Methionine on Milk Performance and Milk Constituents of Lactating Donkeys

Animals
This study investigated the effects of adding methionine (Met) in milk production and the milk and blood metabolites of lactating donkeys. Eighteen healthy multiparous donkeys in early-stage lactation were selected for this study.
Fei Huang, Xinyi Du, Zongjie Ma, Guiqin Liu, Changfa Wang, Miaomiao Zhou   +5 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source