Results 61 to 70 of about 12,286,981 (307)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Tree Shade Improves Milking Performance, Apparent Digestibility, Antioxidant Capacity, and Immunity of Dairy Cows in Open Sheds

Animals
Dairy cows are suffering from heat stress (HS) worldwide, and this has become a continual challenge in dairy production systems. The objective of this study was to investigate the effects of the shade of poplar trees on alleviating HS via measuring milk ...
Jianjie Li, Yinghao Zhou, Man Feng, Lianjie Song, Yuqing Liu, Haitong Yang, Lu Zhang, Ao Zhang, Xinnian Zhao, Xinsheng Sun, Yuhong Gao, Jianjun Guo   +11 more
doaj   +1 more source

Lactational Performance of Manipuri Women

Journal of Nepal Medical Association, 2003
A study was conducted to measure the volume of breast milk output of 26 lactating women and to estimatethe period of its adequacy as the sole food for the infants. Child-mother pairs were selected on voluntarybasis from amongst mothers who delivered in the Regional Institute of Medical Sciences Hospital, Imphal,Manipur (India).
NC Luwang, TA Singh, LI Devi
openaire   +3 more sources

Juvenile Huntington Disease With Cerebellar‐Predominant Atrophy Identified by Genome Sequencing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Juvenile Huntington disease accounts for a small fraction of Huntington disease cases and is driven by the largest trinucleotide repeat expansions. We describe a 6‐year‐old boy with progressive global regression, generalized dystonia, and epilepsy, in whom serial imaging showed striking cerebellar‐predominant atrophy with an initially normal ...
Enrique Gonzalez Saez‐Diez, Amy Tam, Siofra Carty, Monica Ferrer Socorro, Kathryn Yang, Darius Ebrahimi‐Fakhari   +5 more
wiley   +1 more source

Effect of heat stress in late gestation on subsequent lactation performance and mammary cell gene expression of Saanen goats.

Journal of Dairy Science, 2019
Little is known about the effects of heat stress during the late gestation period on lactation in dairy goats. For this reason, 32 Saanen goats were randomly assigned to 1 of 2 groups, control (CT; n = 16) or heat stress (HS; n = 16), during late ...
H. B. Hooper, P. F. dos S. Silva, S. D. de Oliveira, G. K. F. Meringhe, P. Lacasse, J. Negrão   +5 more
semanticscholar   +1 more source

Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li, Zhi‐Xian Ye, Xuan‐Yu Chen, Liang‐Liang Qiu, Zhi‐li Chen, Yu‐Sen Qiu, Wei Lin, Ru‐Ying Yuan, Xin‐Tong Yu, Chun‐Yu Huang, Xin‐Yuan Chen, Min‐Ting Lin, Jian‐Ping Hu, Wan‐Jin Chen, Ning Wang, Shao‐Bo Yao, Shi‐Rui Gan, Ying Fu   +17 more
wiley   +1 more source

Impact of multi-enzyme supplementation on sow reproductive performance, apparent nutrient digestibility, and lactation performance

South African Journal of Animal Science
This study evaluated the effects of supplementing a reduced-energy diet with a compound enzyme on sow performance, nutrient utilisation, and faecal characteristics.
Guanglei Cong, Chunxue Liu, Shuangshuang Xia, Junbo Li, Ifen Hung   +4 more
doaj   +1 more source

Clinical Characteristics and Concordance of Anti‐MDA5 Antibodies: A Multicenter Australian Study

Arthritis Care &Research, EarlyView.
Objective In Australia, anti‐MDA5 antibodies are exclusively tested by a line immunoblot assay (LIA). The clinical concordance of an LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies. Methods Electronic records of a multisite cohort (patients
Syed B. Ali, Thomas Khoo, Keeran Shivakumar, Adam Caroll, Lauren Hender, Dimitra Beroukas, Kim Griggs, Celina Jin, Theo De Malmanche, Jessica Day, Gabor Major, Vidya Limaye   +11 more
wiley   +1 more source

Generative Artificial Intelligence Utilization and Perspectives Among Reproductive‐Age Women With Systemic Autoimmune and Rheumatic Diseases

Arthritis Care &Research, EarlyView.
Objective Reproductive‐age women with systemic autoimmune and rheumatic diseases (SARDs) have unique information needs related to their SARDs and reproductive health. We sought to understand their use of and receptivity to current and hypothetical generative artificial intelligence (AI) tools for health information‐seeking. Methods We conducted a cross‐
Mariam Arif, Catherine Wright, Samantha Rodriguez, Sarah Graves, Tamar Krishnamurti, Mehret Birru Talabi   +5 more
wiley   +1 more source

Effects of Methionine on Milk Performance and Milk Constituents of Lactating Donkeys

Animals
This study investigated the effects of adding methionine (Met) in milk production and the milk and blood metabolites of lactating donkeys. Eighteen healthy multiparous donkeys in early-stage lactation were selected for this study.
Fei Huang, Xinyi Du, Zongjie Ma, Guiqin Liu, Changfa Wang, Miaomiao Zhou   +5 more
doaj   +1 more source