Results 91 to 100 of about 47,243 (214)

Dynamics and compositional profiles of human milk oligosaccharides in mothers with gestational diabetes mellitus across lactation

open access: yesFrontiers in Nutrition
PurposeThis study aimed to systematically clarify the changes in the concentrations of human milk oligosaccharides (HMOs) in mothers with gestational diabetes mellitus (GDM) and the differences from healthy mothers.MethodsA total of 156 human milk ...
Shihao Guo   +13 more
doaj   +1 more source

Blood-Stained Colostrum: A Rare Phenomenon at an Early Lactation Stage. [PDF]

open access: yesChildren (Basel), 2022
Katarzyna W   +6 more
europepmc   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang   +8 more
wiley   +1 more source

Organic Nanozyme‐Embedded Biotherapeutic Thermosensitive Hydrogel for Extracellular GSH Depletion and Postoperative Tumor Suppression

open access: yesAdvanced Science, EarlyView.
A temperature‐sensitive hydrogel loaded with cyanine nanozymes and Escherichia coli is locally injected into postoperative tumor resection beds. Upon light irradiation, synergistic PTT and PDT work with cascaded reactive oxygen species to deplete extracellular GSH, eliminate residual tumor cells, and induce robust antitumor immune responses for ...
Cong Jiang   +10 more
wiley   +1 more source

Longitudinal and Cross-Sectional Studies to Evaluate Changes in Cow Milk Microbiota Over the Lactation Stages

open access: yesActa Veterinaria
To clarify the changes in milk microbiota by lactation stage, i.e., d ays in milk (DIM) for Fresh of 0 to 21, Early (DIM of 22 to 80), Middle (DIM of 81 to 200), and Late (DIM 201 or more) lactation stages in dairy cows, we performed longitudinal (12 ...
Shinozuka Yasunori   +7 more
doaj   +1 more source

Bioactive Protein Profile and Compositional Evolution of Donkey Milk Across Lactation Reflecting Its Nutritional and Functional Food Value

open access: yesFoods
Donkey milk is increasingly recognized as a functional food due to its unique nutritional profile and richness in bioactive compounds. This longitudinal observational study investigated changes in both chemical composition (total solids, protein, fat ...
Ana-Maria Plotuna   +7 more
doaj   +1 more source

p300‐Mediated H3K18 Lactylation Drives Radiation‐Induced Pulmonary Fibrosis via VIRMA‐Dependent m6A Modification of GATA3

open access: yesAdvanced Science, EarlyView.
Radiation triggers glycolytic reprogramming in alveolar epithelial type II cells, causing pathological lactate accumulation. This metabolic stress drives p300‐mediated H3K18 lactylation at the VIRMA promoter, activating transcription. Elevated VIRMA enriches m6A on GATA3 mRNA, which YTHDF1 stabilizes, ultimately driving epithelial–mesenchymal ...
Junxuan Yi   +8 more
wiley   +1 more source

Effects of season, parity and stage of lactation on yield, composition and microbial quality of milk from camels raised in Tsabong, Botswana

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux
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Eyassu Seifu   +16 more
doaj   +1 more source

AI‐Assisted Tumor Boundary Delineation via Targeted Ultrasmall Iron Oxide Nanoprobe for High‐Contrast HER2‐Positive Tumor Imaging

open access: yesAdvanced Science, EarlyView.
A novel targeted and pH‐responsive MRI contrast agent was integrated with a 3D nnU‐Net deep learning framework to enable accurate delineation of tumor boundary morphology in HER2‐positive breast cancer imaging. ABSTRACT Breast cancer continues to be a leading cause of cancer‐related mortality in women globally, where precise diagnosis and clear tumor ...
Jiaying Zheng   +7 more
wiley   +1 more source

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