Results 91 to 100 of about 81,410 (341)

Dual‐Key Genetic Circuit Enables Stable and Self‐Regulated Engineered Bacteria for the Treatment of Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
A self‐regulated Escherichia coli Nissle 1917 strain equipped with a dual‐key genetic circuit achieved antibiotic‐free stability and programmable lysis for therapeutic protein delivery. By co‐expressing an IL‐2 mutant and Amuc_1100, the engineered bacteria restored immune balance and epithelial integrity, providing a safe and precise approach for ...
Shuaijie Ding   +6 more
wiley   +1 more source

comparsion of lhe Elfectiveness of Lactobecillt Sappositoty with Metronidazol vagind rablet on Yaginal p*,.Sigrrs and Symptoms of Bacteriat vaginosis. [PDF]

open access: yes
Background: Bacterial vaginosis is characterized by a imbalance in the vaginal ecosystem, this change is due to an overgrowth of anaerobic bacteria and a contaminant decrease in the number of lactobacilli and increase in vaginal pH more that 4.5. Normal
ایوان بقاء, ریحانه   +3 more
core  

Epidemiology of mixed vaginitis and its management [PDF]

open access: yes, 2013
Vaginitis is a common reason for visits to a health care provider, accounting for 6 million visits per year. Symptoms associated with vaginitis can cause substantial distress, resulting in time lost from work and altered self-esteem.
Galea, Therese
core  

Bridging Green Chemistry and Circular Economy: A Pathway to Sustainable Polyester Plastics Through Feedstock, Synthesis, and Waste Upcycling

open access: yesAdvanced Science, EarlyView.
This review summarizes green and low‐carbon strategies throughout the entire life cycle of polyester plastics, including sustainable monomer synthesis, optimization polymerization, efficient recycling, and advanced upcycling technologies. The synergistic implementation of these strategies is expected to significantly promote the development of a ...
Jinzhou Li   +5 more
wiley   +1 more source

Pathogenic Lactobacilli [PDF]

open access: yesJournal of Medical Microbiology, 1973
M E, Sharpe, L R, Hill, S P, Lapage
openaire   +2 more sources

Isolation and Characterization of Lactic Acid Bacteria From Milk and Their Effects on the Pathogenic Bacteria

open access: yesResearch in Molecular Medicine, 2020
Background: Probiotics are “live microbial cells” that are beneficial for human and animal health. Lactobacilli are such a diverse group of bacteria with similar metabolic and physiological characteristics, and constitute important and beneficial gut ...
Ciamak Ghazaei
doaj  

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

open access: yesAdvanced Science, EarlyView.
ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin   +9 more
wiley   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu   +11 more
wiley   +1 more source

Programming Next‐Generation Synthetic Biosensors by Genetic Circuit Design

open access: yesAdvanced Science, EarlyView.
Synthetic biology enables genetic circuit‐based biosensing to detect diverse targets, process signals, and transduce them into readable outputs or intracellular regulatory activities. However, field deployment and real‐world application of such synthetic biosensors face considerable challenges in sensitivity, specificity, speed, stability, and ...
Yuanli Gao   +4 more
wiley   +1 more source

In situ gastrointestinal protection against anthrax edema toxin by single-chain antibody fragment producing lactobacilli

open access: yesBMC Biotechnology, 2011
Background Anthrax is caused by the bacterium Bacillus anthracis and is regarded as one of the most prominent bioterrorism threats. Anthrax toxicity is induced by the tripartite toxin complex, composed of the receptor-binding anthrax protective antigen ...
Andersen Kasper   +4 more
doaj   +1 more source

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