Results 1 to 10 of about 46,970 (197)

Methylation Regulation of TLR3 on Immune Parameters in Lung Adenocarcinoma

open access: yesFrontiers in Oncology, 2021
This study aims to analyze the methylation regulation of TLR3 in lung adenocarcinoma (LUAD) and to explore the association of TLR3 expression with immune microenvironment.
Zhi Zhang, Xuemei Zhang, Qinqin Tian
exaly   +3 more sources

Extracellular RNAs-TLR3 Signaling Contributes to Cognitive Impairment After Chronic Neuropathic Pain in Mice

open access: yesSignal Transduction and Targeted Therapy, 2023
Chronic pain is often associated with cognitive decline, which could influence the quality of the patient’s life. Recent studies have suggested that Toll-like receptor 3 (TLR3) is crucial for memory and learning.
Chan Chen, Xiaobo Mao, Yi Teng
exaly   +2 more sources

Stimulating effect of double-stranded yeast RNA on the activity of interferon system genes

open access: yesМедицинская иммунология, 2021
Influence of double-stranded RNA (dsRNA) from Saccharomyces cerevisiae yeast upon expression levels of the macrophage genes encoding TLR3 receptor, interferons alpha and beta (IFNα, IFNβ), 2’,5’-oligoadenylate synthetase (OAS) and protein kinase R (PKR ...
A. V. Bateneva   +3 more
doaj   +1 more source

The Role of MEG3 in the Activation of Toll Like Receptor 3 in Prostate Cancer Cells

open access: yesSakarya Tıp Dergisi, 2021
Objective: Prostate cancer accounts for approximately 10% of new cases diagnosed in men worldwide. Toll like receptors (TLRs) play a crucial role in the progression of cancer.
Gamze Güney Eskiler   +5 more
doaj   +1 more source

TLR3 serves as a novel diagnostic and prognostic biomarker and is closely correlated with immune microenvironment in three types of cancer

open access: yesFrontiers in Genetics, 2022
Background: Toll-like receptor 3 (TLR3) plays an important role in both innate and adaptive immunity, but the prognostic value of TLR3 in heterogeneous tumors and the correlations between TLR3 expression and immune infiltration of heterogeneous tumors ...
Xiong Zou   +12 more
doaj   +1 more source

Microcefalia por Zika un problema latente: Reporte de Caso y Aspectos Moleculares

open access: yesInfectio, 2020
We present the case of a 20-day-old patient from Cartagena (Bolívar), hospitalized for presenting a 6-day fever associated with respiratory symptoms with normal neurological evaluation. The obstetric ultrasound showed a microcephaly with a percentile of
Oscar Patiño
doaj   +1 more source

HLA-A*0206 with TLR3 polymorphisms exerts more than additive effects in Stevens-Johnson syndrome with severe ocular surface complications. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Stevens-Johnson syndrome (SJS) is an acute inflammatory vesiculobullous reaction of the skin and mucosa, often including the ocular surface, and toxic epidermal necrolysis (TEN) occurs with its progression.
Mayumi Ueta   +6 more
doaj   +1 more source

Roles of Toll-Like Receptor 3 in Human Tumors

open access: yesFrontiers in Immunology, 2021
Toll-like receptor 3 (TLR3) is an important member of the TLR family, which is an important group of pathogen-associated molecular patterns. TLR3 can recognize double-stranded RNA and induce activation of NF-κB and the production of type I interferons ...
Xin Zheng, Song Li, Hui Yang
doaj   +1 more source

Both MicroRNA-155 and Virus-Encoded MiR-155 Ortholog Regulate TLR3 Expression. [PDF]

open access: yesPLoS ONE, 2015
MicroRNA-155 (miR-155) has been as an important controller of TLR3 signalling. However, the interactions between miR-155 and TLR3 are poorly understood. Here, we focused on the regulation of the relationship between miR-155 and TLR3.
Xuming Hu   +5 more
doaj   +1 more source

Small molecule SMU-CX24 targeting toll-like receptor 3 counteracts inflammation: A novel approach to atherosclerosis therapy

open access: yesActa Pharmaceutica Sinica B, 2022
Toll-like receptor 3 (TLR3), as an important pattern recognition receptor (PRR), dominates the innate and adaptive immunity regulating many acute and chronic inflammatory diseases.
Xiaohong Cen   +9 more
doaj   +1 more source

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