Frontiers in Genetics, 2022 Background: Toll-like receptor 3 (TLR3) plays an important role in both innate and adaptive immunity, but the prognostic value of TLR3 in heterogeneous tumors and the correlations between TLR3 expression and immune infiltration of heterogeneous tumors ...
Xiong Zou, Zengnan Mo
exaly +3 more sources
Methylation Regulation of TLR3 on Immune Parameters in Lung Adenocarcinoma
Frontiers in Oncology, 2021 This study aims to analyze the methylation regulation of TLR3 in lung adenocarcinoma (LUAD) and to explore the association of TLR3 expression with immune microenvironment.
Zhi Zhang, Xuemei Zhang
exaly +3 more sources
Computational design of a multiepitope vaccine targeting VP1 and VP2 capsid proteins of simian virus 40 (SV40) for enhanced immune activation [PDF]
Open MedicineThis study aimed to design and evaluate a computationally constructed multiepitope vaccine targeting Simian Virus 40 (SV40) by predicting and selecting immunogenic B-cell and T-cell epitopes derived from the VP1 and VP2 capsid proteins using ...
Naveed Muhammad +10 more
doaj +2 more sources
Stimulating effect of double-stranded yeast RNA on the activity of interferon system genes
Медицинская иммунология, 2021 Influence of double-stranded RNA (dsRNA) from Saccharomyces cerevisiae yeast upon expression levels of the macrophage genes encoding TLR3 receptor, interferons alpha and beta (IFNα, IFNβ), 2’,5’-oligoadenylate synthetase (OAS) and protein kinase R (PKR ...
A. V. Bateneva +3 more
doaj +1 more source
The Role of MEG3 in the Activation of Toll Like Receptor 3 in Prostate Cancer Cells
Sakarya Tıp Dergisi, 2021 Objective: Prostate cancer accounts for approximately 10% of new cases diagnosed in men worldwide. Toll like receptors (TLRs) play a crucial role in the progression of cancer.
Gamze Güney Eskiler +5 more
doaj +1 more source
Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells [PDF]
, 2013 Persistent infections with hepatitis C virus (HCV) may result in life-threatening liver disease, including cirrhosis and cancer, and impose an important burden on human health.
Dansako, Hiromichi +6 more
core +8 more sources
HLA-A*0206 with TLR3 polymorphisms exerts more than additive effects in Stevens-Johnson syndrome with severe ocular surface complications. [PDF]
PLoS ONE, 2012 BACKGROUND: Stevens-Johnson syndrome (SJS) is an acute inflammatory vesiculobullous reaction of the skin and mucosa, often including the ocular surface, and toxic epidermal necrolysis (TEN) occurs with its progression.
Mayumi Ueta +6 more
doaj +1 more source
Microcefalia por Zika un problema latente: Reporte de Caso y Aspectos Moleculares
Infectio, 2020 We present the case of a 20-day-old patient from Cartagena (Bolívar), hospitalized for presenting a 6-day fever associated with respiratory symptoms with normal neurological evaluation. The obstetric ultrasound showed a microcephaly with a percentile of
Oscar Patiño
doaj +1 more source
Roles of Toll-Like Receptor 3 in Human Tumors
Frontiers in Immunology, 2021 Toll-like receptor 3 (TLR3) is an important member of the TLR family, which is an important group of pathogen-associated molecular patterns. TLR3 can recognize double-stranded RNA and induce activation of NF-κB and the production of type I interferons ...
Xin Zheng, Song Li, Hui Yang
doaj +1 more source
Both MicroRNA-155 and Virus-Encoded MiR-155 Ortholog Regulate TLR3 Expression. [PDF]
PLoS ONE, 2015 MicroRNA-155 (miR-155) has been as an important controller of TLR3 signalling. However, the interactions between miR-155 and TLR3 are poorly understood. Here, we focused on the regulation of the relationship between miR-155 and TLR3.
Xuming Hu +5 more
doaj +1 more source