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dsRNA-Seq: Identification of Viral Infection by Purifying and Sequencing dsRNA [PDF]
Viruses, 2019 RNA viruses are a major source of emerging and re-emerging infectious diseases around the world. We developed a method to identify RNA viruses that is based on the fact that RNA viruses produce double-stranded RNA (dsRNA) while replicating. Purifying and
Carolyn J. Decker +10 more
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Diversity and Current Classification of dsRNA Bacteriophages
Viruses, 2023 Half a century has passed since the discovery of Pseudomonas phage phi6, the first enveloped dsRNA bacteriophage to be isolated. It remained the sole known dsRNA phage for a quarter of a century and the only recognised member of the Cystoviridae family ...
Sari Mäntynen +2 more
doaj +4 more sources
SID-1 is a dsRNA-selective dsRNA-gated channel [PDF]
RNA, 2011 Systemic RNAi in Caenorhabditis elegans requires the widely conserved transmembrane protein SID-1 to transport RNAi silencing signals between cells. When expressed in Drosophila S2 cells, C. elegans SID-1 enables passive dsRNA uptake from the culture medium, suggesting that SID-1 functions as a channel for the transport of double-stranded RNA (dsRNA ...
Shih, Joseph D., Hunter, Craig
core +7 more sources
dsRNA Uptake in Adult Drosophila [PDF]
, 2011 RNA interference (RNAi) is a conserved sequence-specific gene silencing mechanism that is induced by double-stranded RNA (dsRNA). The development of methods that allow internalization of dsRNA and concomitant silencing of the desired gene has not stopped since the first demonstration of RNAi in Caenorhabditis elegans.
Obadia, Benjamin, Saleh, Maria-Carla
openaire +4 more sources
Frontiers in Immunology, 2018 Viruses across genome types produce long dsRNA molecules during replication [viral (v-) dsRNA]. dsRNA is a potent signaling molecule and inducer of type I interferon (IFN), leading to the production of interferon-stimulated genes (ISGs), and a protective
Sarah J Poynter +2 more
exaly +3 more sources
A capsidless (+)RNA yadokarivirus hosted by a dsRNA virus is infectious as particles, cDNA, and dsRNA [PDF]
Journal of VirologyABSTRACT Capsidless yadokariviruses (members of the order Yadokarivirales ) with (+)RNA genomes divert the capsid of their partner icosahedral double-stranded RNA (dsRNA) viruses in different families of the order Ghabrivirales into the ...
Muhammad Fadli +5 more
openaire +5 more sources
Pesticide Biochemistry and Physiology, 2021 Lepidopteran insects are highly refractory to oral RNA interference (RNAi). Degradation, impaired cellular uptake and intracellular transport of double-stranded RNA (dsRNA) are considered the major factors responsible for the reduced RNAi efficiency in ...
Kristof De Schutter +2 more
exaly +2 more sources
Application of Double-stranded RNA (dsRNA) Produced by E. coli HT115 (DE3) and Vector L4440 in Reverse Genetics Studies in Insects [PDF]
Journal of Genetic Resources, 2023 RNA interference is a cellular process for regulating gene expression by double-stranded RNA (dsRNA). In the past two decades, this cellular process has been used as a tool for the temporary knockdown of gene expression to study gene function in reverse ...
Roohollah Abbasi
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Double-stranded RNAs are promising adjuvants for enhancing immunogenicity of vaccines
Журнал микробиологии, эпидемиологии и иммунобиологии, 2023 Background. The most effective way to prevent infectious diseases is vaccination. Adjuvants contribute to the optimization of the immune response of vaccines.
Olga N. Kaplina +3 more
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The Functional Mechanisms of Toll-Like Receptor 3 and Its Implications in Digestive System Tumors
Frontiers in Bioscience-Landmark, 2023 Toll-like receptor 3 (TLR3) is a prominent member of the Toll-like receptor (TLR) family and has the ability to recognize and bind intracellular double-stranded RNA (dsRNA).
Bin Han +7 more
doaj +1 more source