Results 1 to 10 of about 56,868 (220)

Understanding Viral dsRNA-Mediated Innate Immune Responses at the Cellular Level Using a Rainbow Trout Model

open access: yesFrontiers in Immunology, 2018
Viruses across genome types produce long dsRNA molecules during replication [viral (v-) dsRNA]. dsRNA is a potent signaling molecule and inducer of type I interferon (IFN), leading to the production of interferon-stimulated genes (ISGs), and a protective
Stephanie Dewitte-Orr   +1 more
exaly   +3 more sources

Efficiency of Different Methods for dsRNA Delivery in Cotton Bollworm (Helicoverpa armigera)

open access: yesJournal of Integrative Agriculture, 2014
RNAi trigged by dsRNA not only facilitates the development of molecular biology, but also initiates a new way for pest control by silence of fatal genes.
Zhaojun Han
exaly   +3 more sources

Application of Double-stranded RNA (dsRNA) Produced by E. coli HT115 (DE3) and Vector L4440 in Reverse Genetics Studies in Insects [PDF]

open access: yesJournal of Genetic Resources, 2023
RNA interference is a cellular process for regulating gene expression by double-stranded RNA (dsRNA). In the past two decades, this cellular process has been used as a tool for the temporary knockdown of gene expression to study gene function in reverse ...
Roohollah Abbasi
doaj   +1 more source

Double-stranded RNAs are promising adjuvants for enhancing immunogenicity of vaccines

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2023
Background. The most effective way to prevent infectious diseases is vaccination. Adjuvants contribute to the optimization of the immune response of vaccines.
Olga N. Kaplina   +3 more
doaj   +1 more source

The Functional Mechanisms of Toll-Like Receptor 3 and Its Implications in Digestive System Tumors

open access: yesFrontiers in Bioscience-Landmark, 2023
Toll-like receptor 3 (TLR3) is a prominent member of the Toll-like receptor (TLR) family and has the ability to recognize and bind intracellular double-stranded RNA (dsRNA).
Bin Han   +7 more
doaj   +1 more source

Phenotype remodeling in neutrophilic granulocyte subsets CD64-CD32+CD16+CD11B+NG, CD64+CD32+CD16+CD11B+NG in de novo experimental model of viral-bacterial infection in vitro

open access: yesИнфекция и иммунитет, 2021
A search for new targeted therapeutic strategies based on examining immunopathogenetic mechanisms for emerging co-infections is relevant and may further contribute not only to optimizing choice of immunotropic drugs, but also to achieving positive ...
I. V. Nesterova   +6 more
doaj   +1 more source

Systemic spreading of exogenous applied RNA biopesticides in the crop plant Hordeum vulgare [PDF]

open access: yesExRNA, 2020
Background: Small (s) RNA molecules are crucial factors in the communication between hosts and their interacting pathogens/pests that can modulate both host defense and microbial virulence/pathogenicity known as cross-kingdom RNA interference (ckRNAi ...
D. Biedenkopf   +6 more
doaj   +1 more source

Biological control of pathogenic fungi: Can mycoviruses play an important role? [PDF]

open access: yesJournal of Central European Agriculture, 2022
In the past few years, huge economic and environmental losses have resulted by fungal pathogens in agriculture and food production worldwide. Fungal toxins also pose a threat for food production and animal health.
Tomáš Tonka   +2 more
doaj   +1 more source

Psychrophilic phage VSW-3 RNA polymerase reduces both terminal and full-length dsRNA byproducts in in vitro transcription

open access: yesRNA Biology, 2022
RNA research and applications are underpinned by in vitro transcription (IVT), but RNA impurities resulting from the enzymatic reagents severely impede downstream applications. To improve the stability and purity of synthesized RNA, we have characterized
Heng Xia   +6 more
doaj   +1 more source

Symptomatic, widespread, and inconspicuous: new detection of tomato fruit blotch virus

open access: yesPhytopathologia Mediterranea, 2023
Tomato production is an important part of the Swiss vegetable production with most tomato crops grown in greenhouses. Tomato plants are vulnerable to diseases caused by viruses, which can have significant impacts on crop production.
Arnaud G. BLOUIN   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy