Results 21 to 30 of about 68,502 (270)

Stimulating effect of double-stranded yeast RNA on the activity of interferon system genes

open access: yesМедицинская иммунология, 2021
Influence of double-stranded RNA (dsRNA) from Saccharomyces cerevisiae yeast upon expression levels of the macrophage genes encoding TLR3 receptor, interferons alpha and beta (IFNα, IFNβ), 2’,5’-oligoadenylate synthetase (OAS) and protein kinase R (PKR ...
A. V. Bateneva   +3 more
doaj   +1 more source

Mathematical modelling of OAS2 activation by dsRNA and effects of dsRNA lengths

open access: yesAIMS Mathematics, 2021
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Deokro Lee   +4 more
openaire   +2 more sources

RNAi-Mediated Management of Whitefly Bemisia tabaci by Oral Delivery of Double-stranded RNAs

open access: yesProceedings, 2019
The whitefly, Bemisia tabaci (Hemiptera: Aleyrodidae) is a significant global pest of economically important vegetable, fibre, and ornamental crops. Whiteflies directly damage the plants by piercing and sucking essential nutrients, indirectly through ...
Ritesh G Jain   +2 more
doaj   +1 more source

Double-stranded RNA elements associated with the MVX disease of Agaricus bisporus [PDF]

open access: yes, 2003
Double-stranded RNA (dsRNA) has been isolated from Agaricus bisporus fruit bodies exhibiting a wide range of disease symptoms. The symptoms which occurred singularly or in combination included; bare cropping areas on commercial beds (primordia disruption)
Adie, Bruce A. T.   +4 more
core   +1 more source

Mechanism of PKR Activation by dsRNA [PDF]

open access: yesJournal of Molecular Biology, 2008
Protein kinase R (PKR) is a central component of the interferon antiviral defense pathway. Upon binding double-stranded RNA (dsRNA), PKR undergoes autophosphorylation reactions that activate the kinase. PKR then phosphorylates eukaryotic initiation factor 2alpha, thus inhibiting protein synthesis in virally infected cells.
Peter A, Lemaire   +3 more
openaire   +2 more sources

Double strand RNA-mediated RNA interference through feeding in larval gypsy moth, Lymantria dispar (Lepidoptera: Erebidae)

open access: yesEuropean Journal of Entomology, 2017
RNA interference (RNAi) technology uses dsRNAs to silence specific targeted genes by downregulating their expression. It has become a potent tool for functional and regulatory studies of insect genes and has potential to be applied for insect control ...
Saikat Kumar B. GHOSH   +1 more
doaj   +1 more source

Structural basis for Dicer-like function of an engineered RNase III variant and insights into the reaction trajectory of two-Mg2+-ion catalysis

open access: yesRNA Biology, 2022
The RNase III family of dsRNA-specific endonucleases is exemplified by prokaryotic RNase III and eukaryotic Rnt1p, Drosha, and Dicer. Structures of Aquifex aeolicus RNase III (AaRNase III) and Saccharomyces cerevisiae Rnt1p (ScRnt1p) show that both ...
Sudhaker Dharavath   +2 more
doaj   +1 more source

Microinjection of dsRNA in Tardigrades [PDF]

open access: yesCold Spring Harbor Protocols, 2018
Classical genetic analysis in the tardigrade Hypsibius exemplaris is a challenge because these animals are parthenogens. The publication of the H. exemplaris genome has facilitated the study of targeted genes by RNA interference (RNAi), a robust mechanism to disrupt gene function. This protocol describes microinjection of double-stranded RNA (dsRNA) in
openaire   +2 more sources

RNAi-mediated gene silencing in Rhynchophorus ferrugineus (Oliver) (Coleoptera: Curculionidae)

open access: yesOpen Life Sciences, 2017
RNA interference (RNAi) is a powerful strategy for gene function analysis, and it is also widely studied in view of a promising use in pest control. The red palm weevil, Rhynchophorus ferrugineus (Oliver) (Coleoptera: Curculionidae), is one of the most ...
Laudani Francesca   +7 more
doaj   +1 more source

An Investigation of Innate Immune Response of Human Blood Macrophage to Sense and Antisense dsRNA

open access: yesTrends in Peptide and Protein Sciences, 2016
Silencing of gene expression by siRNA (small interfering RNA) is a powerful approach used to study the genetic analysis and functional roles of mammalian genes.
Nasrin Mohajeri   +7 more
doaj   +1 more source

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