Results 21 to 30 of about 119,642 (302)
Cold Spring Harbor Perspectives in Biology, 2019 Long double-stranded RNAs (dsRNAs) are abundantly expressed in animals, in which they frequently occur in introns and 3' untranslated regions of mRNAs. Functions of long, cellular dsRNAs are poorly understood, although deficiencies in adenosine deaminases that act on RNA, or ADARs, promote their recognition as viral dsRNA and an aberrant immune ...
Daniel P, Reich, Brenda L, Bass
openaire +2 more sources
RNAi-based pest control: Production, application and the fate of dsRNA
Frontiers in Bioengineering and Biotechnology, 2022 The limitations of conventional pesticides have raised the demand for innovative and sustainable solutions for plant protection. RNA Interference (RNAi) triggered by dsRNA has evolved as a promising strategy to control insects in a species-specific ...
Li He, Yanna Huang, Xueming Tang
semanticscholar +1 more source
A prenylated dsRNA sensor protects against severe COVID-19
Science, 2021 Description The bat connection The heterogeneity of COVID-19 makes it challenging to predict the course of infection in an individual. Upon virus infection, interferons (IFNs) generate the initial signals for cellular defenses.
Arthur Wickenhagen +47 more
semanticscholar +1 more source
RNA Biology, 2022 RNA research and applications are underpinned by in vitro transcription (IVT), but RNA impurities resulting from the enzymatic reagents severely impede downstream applications. To improve the stability and purity of synthesized RNA, we have characterized
Heng Xia +6 more
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Multiple liquid crystalline geometries of highly compacted nucleic acid in a dsRNA virus
Nature, 2019 Serban L Ilca +2 more
exaly +2 more sources
Advances in nanocarriers to improve the stability of dsRNA in the environment
Frontiers in Bioengineering and Biotechnology, 2022 RNAi technology, known as a revolutionary technology in the history of pesticides, has been identified as a very promising novel approach for crop protection, which is of great significance for achieving the sustainable agricultural development of the ...
Wenling Yang +4 more
semanticscholar +1 more source
Symptomatic, widespread, and inconspicuous: new detection of tomato fruit blotch virus
Phytopathologia Mediterranea, 2023 Tomato production is an important part of the Swiss vegetable production with most tomato crops grown in greenhouses. Tomato plants are vulnerable to diseases caused by viruses, which can have significant impacts on crop production.
Arnaud G. BLOUIN +5 more
doaj +1 more source
Off-target effects of RNAi correlate with the mismatch rate between dsRNA and non-target mRNA
RNA Biology, 2021 RNAi is a potent technique for the knockdown of target genes. However, its potential off-target effects limit the widespread applications in both reverse genetic analysis and genetic manipulation.
Jiasheng Chen +7 more
semanticscholar +1 more source
Turkish Journal of Forestry, 2020 Heterobasidion annosum Fr. Bref. sensu lato is a highly destructive disease factor that causes root and root collar rot in the temperate zone of the Northern Hemisphere, especially in coniferous tree species. In the control of Heterobasidion species, the
Ayse Gülden Aday Kaya, Tuğba Doğmuş
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Антибиотики и Химиотерапия, 2023 High variability of influenza viruses requires the development of agents for nonspecific resistance stimulation, along with the development of new drugs for prevention and treatment.
S. G. Gamaley +7 more
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