dsRNA-Seq: Identification of Viral Infection by Purifying and Sequencing dsRNA [PDF]
Viruses, 2019 RNA viruses are a major source of emerging and re-emerging infectious diseases around the world. We developed a method to identify RNA viruses that is based on the fact that RNA viruses produce double-stranded RNA (dsRNA) while replicating. Purifying and
Carolyn J. Decker +10 more
doaj +3 more sources
Double-Stranded RNA Attenuates the Barrier Function of Human Pulmonary Artery Endothelial Cells [PDF]
, 2013 Circulating RNA may result from excessive cell damage or acute viral infection and can interact with vascular endothelial cells. Despite the obvious clinical implications associated with the presence of circulating RNA, its pathological effects on ...
A Shibamiya +60 more
core +10 more sources
An RNAi-Based Control of Fusarium graminearum Infections Through Spraying of Long dsRNAs Involves a Plant Passage and Is Controlled by the Fungal Silencing Machinery [PDF]
, 2016 Meeting the increasing food and energy demands of a growing population will require the development of ground-breaking strategies that promote sustainable plant production.
Abdellatef, Eltayb +13 more
core +19 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2017 Xufang Deng +2 more
exaly +2 more sources
Biological control of pathogenic fungi: Can mycoviruses play an important role? [PDF]
Journal of Central European Agriculture, 2022 In the past few years, huge economic and environmental losses have resulted by fungal pathogens in agriculture and food production worldwide. Fungal toxins also pose a threat for food production and animal health.
Tomáš Tonka +2 more
doaj +1 more source
The competitive landscape of the dsRNA world.
Molecules and Cells, 2023 The ability to sense and respond to infection is essential for life. Viral infection produces double-stranded RNAs (dsRNAs) that are sensed by proteins that recognize the structure of dsRNA.
Kyle A. Cottrell +2 more
semanticscholar +1 more source
Pathogenic tau–induced transposable element–derived dsRNA drives neuroinflammation
Science Advances, 2023 Deposition of tau protein aggregates in the brain of affected individuals is a defining feature of “tauopathies,” including Alzheimer’s disease.
Elizabeth Ochoa +6 more
semanticscholar +1 more source
SID-1 is a dsRNA-selective dsRNA-gated channel [PDF]
RNA, 2011 Systemic RNAi in Caenorhabditis elegans requires the widely conserved transmembrane protein SID-1 to transport RNAi silencing signals between cells. When expressed in Drosophila S2 cells, C. elegans SID-1 enables passive dsRNA uptake from the culture medium, suggesting that SID-1 functions as a channel for the transport of double-stranded RNA (dsRNA ...
Shih, Joseph D., Hunter, Craig
openaire +3 more sources
Effects of Nanoparticles on Double-Stranded RNA Stability in Corn Soil [PDF]
, 2018 Double-stranded RNA (dsRNA) can potentially be used as a pesticide because these molecules trigger an immune response called RNA interference (RNAi). If the expression of essential genes matching the dsRNA sequence are silenced, then the pest dies.
Reyanldo, Miriam +7 more
core +5 more sources
Stress granules are shock absorbers that prevent excessive innate immune responses to dsRNA
bioRxiv, 2022 Proper defense against microbial infection depends on the controlled activation of the immune system. This is particularly important for the RIG-I-like receptors (RLRs), which recognize viral dsRNA and initiate antiviral innate immune responses with the ...
Max Paget +11 more
semanticscholar +1 more source