Results 11 to 20 of about 68,502 (270)
Инфекция и иммунитет, 2021 A search for new targeted therapeutic strategies based on examining immunopathogenetic mechanisms for emerging co-infections is relevant and may further contribute not only to optimizing choice of immunotropic drugs, but also to achieving positive ...
I. V. Nesterova +6 more
doaj +1 more source
Next Generation dsRNA-Based Insect Control: Success So Far and Challenges [PDF]
, 2021 RNA interference (RNAi) is a method of gene silencing where dsRNA is digested into small interfering RNA (siRNA) in the presence of enzymes. These siRNAs then target homologous mRNA sequences aided by the RNA-induced silencing complex (RISC).
Singh, S. +5 more
core +1 more source
Systemic spreading of exogenous applied RNA biopesticides in the crop plant Hordeum vulgare [PDF]
ExRNA, 2020 Background: Small (s) RNA molecules are crucial factors in the communication between hosts and their interacting pathogens/pests that can modulate both host defense and microbial virulence/pathogenicity known as cross-kingdom RNA interference (ckRNAi ...
D. Biedenkopf +6 more
doaj +1 more source
Biological control of pathogenic fungi: Can mycoviruses play an important role? [PDF]
Journal of Central European Agriculture, 2022 In the past few years, huge economic and environmental losses have resulted by fungal pathogens in agriculture and food production worldwide. Fungal toxins also pose a threat for food production and animal health.
Tomáš Tonka +2 more
doaj +1 more source
Cold Spring Harbor Perspectives in Biology, 2019 Long double-stranded RNAs (dsRNAs) are abundantly expressed in animals, in which they frequently occur in introns and 3' untranslated regions of mRNAs. Functions of long, cellular dsRNAs are poorly understood, although deficiencies in adenosine deaminases that act on RNA, or ADARs, promote their recognition as viral dsRNA and an aberrant immune ...
Daniel P, Reich, Brenda L, Bass
openaire +2 more sources
RNA Biology, 2022 RNA research and applications are underpinned by in vitro transcription (IVT), but RNA impurities resulting from the enzymatic reagents severely impede downstream applications. To improve the stability and purity of synthesized RNA, we have characterized
Heng Xia +6 more
doaj +1 more source
Turkish Journal of Forestry, 2020 Heterobasidion annosum Fr. Bref. sensu lato is a highly destructive disease factor that causes root and root collar rot in the temperate zone of the Northern Hemisphere, especially in coniferous tree species. In the control of Heterobasidion species, the
Ayse Gülden Aday Kaya, Tuğba Doğmuş
doaj +1 more source
Symptomatic, widespread, and inconspicuous: new detection of tomato fruit blotch virus
Phytopathologia Mediterranea, 2023 Tomato production is an important part of the Swiss vegetable production with most tomato crops grown in greenhouses. Tomato plants are vulnerable to diseases caused by viruses, which can have significant impacts on crop production.
Arnaud G. BLOUIN +5 more
doaj +1 more source
Антибиотики и Химиотерапия, 2023 High variability of influenza viruses requires the development of agents for nonspecific resistance stimulation, along with the development of new drugs for prevention and treatment.
S. G. Gamaley +7 more
doaj +1 more source
Studying the effect of double-stranded RNA upon activity of mouse splenocytes using flow cytometry
Медицинская иммунология, 2023 Ribonucleic acids (RNA), in particular, double-stranded RNAs, due to their ability to modulate innate immune responses, are of undoubted interest in view of their usage as vaccine adjuvants.
E. S. Tsyplenkova +2 more
doaj +1 more source