Results 31 to 40 of about 119,642 (302)
Strategies for the production of dsRNA biocontrols as alternatives to chemical pesticides
Frontiers in Bioengineering and Biotechnology, 2022 Current crop pest control strategies rely on insecticidal and fungicidal sprays, plant genetic resistance, transgenes and agricultural practices.
James Hough +5 more
semanticscholar +1 more source
Studying the effect of double-stranded RNA upon activity of mouse splenocytes using flow cytometry
Медицинская иммунология, 2023 Ribonucleic acids (RNA), in particular, double-stranded RNAs, due to their ability to modulate innate immune responses, are of undoubted interest in view of their usage as vaccine adjuvants.
E. S. Tsyplenkova +2 more
doaj +1 more source
dsRNA-induced condensation of antiviral proteins modulates PKR activity
Proceedings of the National Academy of Sciences of the United States of America, 2022 Significance The presence of dsRNA in the cytosol is a marker of infection and elicits an immune response. One aspect of this immune response is the activation of the eIF2α kinase PKR, which results in translational reprogramming and stress granule ...
Giulia A. Corbet +4 more
semanticscholar +1 more source
Stimulating effect of double-stranded yeast RNA on the activity of interferon system genes
Медицинская иммунология, 2021 Influence of double-stranded RNA (dsRNA) from Saccharomyces cerevisiae yeast upon expression levels of the macrophage genes encoding TLR3 receptor, interferons alpha and beta (IFNα, IFNβ), 2’,5’-oligoadenylate synthetase (OAS) and protein kinase R (PKR ...
A. V. Bateneva +3 more
doaj +1 more source
RNAi-Mediated Management of Whitefly Bemisia tabaci by Oral Delivery of Double-stranded RNAs
Proceedings, 2019 The whitefly, Bemisia tabaci (Hemiptera: Aleyrodidae) is a significant global pest of economically important vegetable, fibre, and ornamental crops. Whiteflies directly damage the plants by piercing and sucking essential nutrients, indirectly through ...
Ritesh G Jain +2 more
doaj +1 more source
On the Role of RNA Amplification in dsRNA-Triggered Gene Silencing
Cell, 2001 Titia Sijen +2 more
exaly +2 more sources
Scientific Reports, 2021 Insecticidal double-stranded RNAs (dsRNAs) silence expression of vital genes by activating the RNA interference (RNAi) mechanism in insect cells. Despite high commercial interest in insecticidal dsRNA, information on resistance to dsRNA is scarce ...
Swati Mishra +17 more
semanticscholar +1 more source
dsRNA Uptake in Adult Drosophila [PDF]
, 2011 RNA interference (RNAi) is a conserved sequence-specific gene silencing mechanism that is induced by double-stranded RNA (dsRNA). The development of methods that allow internalization of dsRNA and concomitant silencing of the desired gene has not stopped since the first demonstration of RNAi in Caenorhabditis elegans.
Obadia, Benjamin, Saleh, Maria-Carla
openaire +2 more sources
RNAi efficiency, systemic properties, and novel delivery methods for pest insect control : what we know so far [PDF]
, 2016 In recent years, the research on the potential of using RNA interference (RNAi) to suppress crop pests has made an outstanding growth. However, given the variability of RNAi efficiency that is observed in many insects, the development of novel approaches
Christiaens, Olivier +3 more
core +2 more sources
Spliceosome-Targeted Therapies Induce dsRNA Responses [PDF]
Immunity, 2021 In a recent issue of Cell, Bowling et al. describe a mechanism by which spliceosome-targeted therapies result in intron-containing transcripts that form double-stranded RNAs (dsRNAs), thereby activating tumor antiviral signaling (viral mimicry) and downstream adaptive immunity.
Charles A, Ishak +2 more
openaire +2 more sources