Results 41 to 50 of about 119,642 (302)
RNA Biology, 2022 The RNase III family of dsRNA-specific endonucleases is exemplified by prokaryotic RNase III and eukaryotic Rnt1p, Drosha, and Dicer. Structures of Aquifex aeolicus RNase III (AaRNase III) and Saccharomyces cerevisiae Rnt1p (ScRnt1p) show that both ...
Sudhaker Dharavath +2 more
doaj +1 more source
European Journal of Entomology, 2017 RNA interference (RNAi) technology uses dsRNAs to silence specific targeted genes by downregulating their expression. It has become a potent tool for functional and regulatory studies of insect genes and has potential to be applied for insect control ...
Saikat Kumar B. GHOSH +1 more
doaj +1 more source
A Facile Method for the Removal of dsRNA Contaminant from In Vitro-Transcribed mRNA
Molecular Therapy: Nucleic Acids, 2019 The increasing importance of in vitro-transcribed (IVT) mRNA for synthesizing the encoded therapeutic protein in vivo demands the manufacturing of pure mRNA products. The major contaminant in the IVT mRNA is double-stranded RNA (dsRNA), a transcriptional
M. Baiersdörfer +6 more
semanticscholar +1 more source
Next Generation dsRNA-Based Insect Control: Success So Far and Challenges
Frontiers in Plant Science, 2021 RNA interference (RNAi) is a method of gene silencing where dsRNA is digested into small interfering RNA (siRNA) in the presence of enzymes. These siRNAs then target homologous mRNA sequences aided by the RNA-induced silencing complex (RISC).
Rahul B. Nitnavare +5 more
semanticscholar +1 more source
RNAi-mediated gene silencing in Rhynchophorus ferrugineus (Oliver) (Coleoptera: Curculionidae)
Open Life Sciences, 2017 RNA interference (RNAi) is a powerful strategy for gene function analysis, and it is also widely studied in view of a promising use in pest control. The red palm weevil, Rhynchophorus ferrugineus (Oliver) (Coleoptera: Curculionidae), is one of the most ...
Laudani Francesca +7 more
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Requirements for fungal uptake of dsRNA and gene silencing in RNAi-based crop protection strategies.
Current Opinion in Biotechnology, 2021 Growing evidence indicates that RNAi is an effective control strategy for agronomically important fungi. To implement RNAi-based crop protection strategies, dsRNA molecules are either sprayed on foliage or generated by genetically engineered plants. Here,
E. Šečić, K. Kogel
semanticscholar +1 more source
Double-stranded RNA elements associated with the MVX disease of Agaricus bisporus [PDF]
, 2003 Double-stranded RNA (dsRNA) has been isolated from Agaricus bisporus fruit bodies exhibiting a wide range of disease symptoms. The symptoms which occurred singularly or in combination included; bare cropping areas on commercial beds (primordia disruption)
Adie, Bruce A. T. +4 more
core +1 more source
Biomolecules, 2020 Grapevine is one of the most important and globally widespread fruit species, with a high impact on the economy of many countries but with an intense environmental effect.
Luca Nerva +3 more
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Gene silencing in tick cell lines using small interfering or long double-stranded RNA [PDF]
, 2012 Gene silencing by RNA interference (RNAi) is an important research tool in many areas of biology. To effectively harness the power of this technique in order to explore tick functional genomics and tick-microorganism interactions, optimised parameters ...
A-C Barnard +57 more
core +4 more sources
An Investigation of Innate Immune Response of Human Blood Macrophage to Sense and Antisense dsRNA
Trends in Peptide and Protein Sciences, 2016 Silencing of gene expression by siRNA (small interfering RNA) is a powerful approach used to study the genetic analysis and functional roles of mammalian genes.
Nasrin Mohajeri +7 more
doaj +1 more source