Results 41 to 50 of about 38,733 (231)

Molecular Pathogenesis of MALT lymphoma [PDF]

, 2011
Mucosa associated lymphoid tissue (MALT) lymphoma is characterized by t(11;18)(q21;q21)/API2-MALT1, t(1;14)(p22;q32)/BCL10-IGH and t(14;18)(q32;q21)/IGH-MALT1, which commonly activate the NF-κB pathway.

core   +2 more sources

Antimicrobial Functions of Lactoferrin Promote Genetic Conflicts in Ancient Primates and Modern Humans.

PLoS Genetics, 2016
Lactoferrin is a multifunctional mammalian immunity protein that limits microbial growth through sequestration of nutrient iron. Additionally, lactoferrin possesses cationic protein domains that directly bind and inhibit diverse microbes.
Matthew F Barber, Zev Kronenberg, Mark Yandell, Nels C Elde   +3 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Antimicrobial potential for the combination of bovine lactoferrin or its hydrolysate with lactoferrin-resistant probiotics against foodborne pathogens

, 2014
Previous reports have shown that several probiotic strains can resist the antibacterial activity of bovine lactoferrin (bLf), but the results are inconsistent.
T.T. Jheng, C.-L. Shyu, F.C. Mao, P.-W. Chen   +3 more
core   +1 more source

Lactoferrin – 50 years on [PDF]

, 2012
It is now some 50 years since iron-binding lactoferrin was first isolated and purified, an event that opened the way to subsequent extensive research on lactoferrin structure and function.
J. V. Zalutsky, V. F. Chekhun, С. Б. Кондрашова, Brock, J.H., V. S. Lukashevich, S. B. Kondrashova, И. В. Залуцкий, Yu. A. Rudnichenko, Ю. А. Рудниченко, В. Ф. Чехун, N. Y. Lukianova, А. А. Басалай, A. A. Basalay, Н. Ю. Лукьянова, В. С. Лукашевич   +14 more
core   +1 more source

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

Lactoferrin-derived peptides antimicrobial activity: an in vitro experiment

, 2020
Antibiotic resistance is a global problem, searching for new antimicrobial agents is an urgent need. In this study, in vitro antibacterial and antimicrobial effects of milk-derived antimicrobial agents, lactoferrin-derived peptides, lactoferricin (Lfc ...
Elena Biasibetti (4394662), Silvia Rapacioli (9377830), Elisa Martello (9377833), Natascia Bruni (4394665)   +3 more
core   +1 more source

Determinants of human milk lactoferrin concentrations in rural Bangladesh.

PLOS Global Public Health
Lactoferrin is an iron-binding glycoprotein in human milk (HM) that reduces the risk of neonatal sepsis. Data from low- and middle-income countries regarding the determinants of HM lactoferrin concentration is limited.
Chloe Andrews, Ingrid Olson, Agata Mp Atayde, Salahuddin Ahmed, Nabidul Haque Chowdhury, Rasheda Khanam, Sayedur Rahman, Lars Bode, Mandy B Belfort, Abdullah H Baqui, Sarbattama Sen, Anne Cc Lee   +11 more
doaj   +1 more source

Advancing Biotherapeutic Treatment of Ulcerative Colitis Using Lipid Mesophases: Formulation Design and Preclinical Validation

Advanced Science, EarlyView.
Lipid mesophases provide a versatile platform for colon‐targeted delivery of biotherapeutics, protecting them from degradation while enhancing mucoadhesion and enabling localized, controlled release to the inflamed mucosa after oral or rectal administration. In a DSS‐induced colitis model, this strategy reduced disease activity, inflammatory biomarkers,
Rafaela Gazzi, Tiziana Cremona, Reto Czekalla, Emily Campbell, Marlene Schwarzfischer, Doris Pöhlmann, Vanessa Dobernig, Gerhard Rogler, Michael Scharl, Alessandra Bergadano, Raffaele Mezzenga, Martin Kuentz, Paola Luciani, Simone Aleandri   +13 more
wiley   +1 more source

Lactoferrin-decorated vs PEGylated zein nanospheres for combined aromatase inhibitor and herbal therapy of breast cancer

, 2018
Objectives: Herein, we propose combined aromatase inhibitor and herbal therapy of breast cancer as a synergistic therapeutic modality. Methods: Zein nanospheres were prepared by phase separation for co-delivery of exemestane and luteolin.
Nazik A. Elgindy (5622071), Maged W. Helmy (822135), Sarah A. El-Lakany (5622068), Marwa M Abu-Serie (5622074), Ahmed O. Elzoghby (5622077)   +4 more
core   +1 more source