Results 51 to 60 of about 862 (134)
Risks for human health related to the presence of plant lectins in food
EFSA Journal, Volume 24, Issue 1, January 2026.Abstract The European Commission asked the European Food Safety Authority (EFSA) to assess the risk related to the presence of plant lectins in food. Based on the available evidence, the CONTAM Panel considered only phytohaemagglutinin (PHA), a legume lectin from beans (Phaseolus sp.), for the risk characterisation.
EFSA Panel on Contaminants in the Food Chain (CONTAM) +30 more
wiley +1 more source
Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.Key Lentinula edodes (Shiitake) metabolites and their therapeutic roles. Lentinic acid, shiitakeols A/B, and lanostanoids show anti‐inflammatory activity; lentinan and latcripin derivatives possess anticancer effects; sterols, β‐glucans, and eritadenine are hepatoprotective.
Bikash Baral
wiley +1 more source
Proteomic analysis of lactosylceramide-enriched membrane microdomains
Trends in Glycoscience and Glycotechnology, 2008 生体膜マイクロドメイン（リピドラフト）はコレステロールとスフィンゴ糖脂質に富む膜上の微小領域で，細胞の内外をつなぐさまざまな細胞反応に関与している。我々はラクトシルセラミドの集積する細胞膜マイクロドメインに焦点を当て，好中球の機能を研究している。好中球の生体膜マイクロドメインは貪食などの機能に関与することが知られているが，その分子メカニズムはまだ十分には明らかにされていない。この総説では生体膜マイクロドメインが機能する際の分子メカニズムを明らかにするために，その構成タンパク質を網羅的に調べる戦略について概説する。
Mitsuaki Yanagida, Kazuhisa Iwabuchi
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Lactosylceramide-enriched glycosphingolipid signaling domain mediates superoxide generation from human neutrophils [PDF]
Blood, 2002 This study is focused on the functional significance of neutrophil lactosylceramide (LacCer)–enriched microdomains, which are involved in the initiation of a signal transduction pathway leading to superoxide generation. Treatment of neutrophils with anti-LacCer antibody, T5A7 or Huly-m13, induced superoxide generation from the cells, which was blocked ...
Kazuhisa, Iwabuchi, Isao, Nagaoka
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The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance
Glia, Volume 73, Issue 12, Page 2338-2352, December 2025.Main Points Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons dunng rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production ...
Rose Follis +2 more
wiley +1 more source
Advanced Science, Volume 12, Issue 41, November 6, 2025.In superficial second‐degree burn wounds, Gb3 turns on genes related to papillary cells through the FGF2 signaling pathway. This increases the ability of cells to break down fibrin and decreases fibrosis, which ultimately prevents scar formation in burn injuries.
Sujie Xie +13 more
wiley +1 more source
Lactosylceramide-enriched Lipid Raft-mediated Infection Immunity
Medical Mycology Journal, 2018 More than 100 years have passed since Elie Metchnikoff discovered phagocytes. As molecular biological techniques have been developed and improved, we have gained deeper knowledge about the molecular mechanisms of immunological responses to invasion. The innate immune system is the inborn defense mechanism and the first line of defense against all kinds
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Ecology and Evolution, Volume 15, Issue 11, November 2025.Genomic regions potentially associated with resistance against imidacloprid in the Colorado potato beetle were identified here using bulked segregant analysis. Candidate genes were then narrowed down using the functional annotation and expression analysis.
Alitha Edison +3 more
wiley +1 more source
Advanced Science, Volume 12, Issue 38, October 13, 2025.A tumor‐penetrating photooncolytic phage is developed for selectively targeting and delivering photosensitizers to GD2‐positive Neuroblastoma cells. Upon light activation, it precisely induces oncolysis of GD2‐positive cells with no effect on GD2‐negative ones.
Suleman Khan Zadran +25 more
wiley +1 more source
Plasma lipidomic alterations during pathogenic SIV infection with and without antiretroviral therapy
Frontiers in ImmunologyIntroductionLipid profiles change in human immunodeficiency virus (HIV) infection and correlate with inflammation. Lipidomic alterations are impacted by multiple non-HIV-related behavioral risk factors; thus, use of animal models in which these ...
Sindhuja Sivanandham +18 more
doaj +1 more source