Calicivirus RNA-Dependent RNA Polymerases: Evolution, Structure, Protein Dynamics, and Function [PDF]
Frontiers in Microbiology, 2019 The Caliciviridae are viruses with a positive-sense, single-stranded RNA genome that is packaged into an icosahedral, environmentally stable protein capsid.
Elena Smertina +5 more
doaj +3 more sources
Widespread occurrence of the non-pathogenic hare calicivirus (HaCV Lagovirus GII.2) in captive-reared and free-living wild hares in Europe. [PDF]
Transbound Emerg Dis, 2021 Abstract The Lagovirus genus comprises both pathogenic viruses as European brown hare syndrome virus (EBHSV‐ GII.1) and rabbit hemorrhagic disease viruses (RHDV‐GI.1 and RHDV2‐GI.2), that principally infect European brown hares (Lepus europeaus) and European rabbits (Oryctolagus cuniculus), respectively, causing severe necrotic hepatitis, spleen ...
Cavadini P +9 more
europepmc +2 more sources
Serological characterisation of Lagovirus virus-like particles originating from native and mutated VP60 of rabbit haemorrhagic disease virus 2 and European brown hare syndrome virus [PDF]
Journal of Veterinary ResearchSince lagoviruses cannot be cultivated in vitro, using expression systems is an alternative and promising way of producing diagnostic viral antigens. It opens up their use as active immunogens for vaccine production.
Krejmer-Rąbalska Martyna +3 more
doaj +2 more sources
First report of GI.1aP-GI.2 recombinants of rabbit hemorrhagic disease virus in domestic rabbits in China. [PDF]
Front Microbiol, 2023 The rabbit hemorrhagic disease virus 2 (RHDV2 or GI.2) is a highly contagious agent leading to lethal disease in rabbits. It frequently recombines with other Lagovirus genus, generating epidemical variants with high pathogenicity.
Li Y +8 more
europepmc +3 more sources
Multiple Introductions of Rabbit Hemorrhagic Disease Virus Lagovirus europaeus/GI.2 in Africa [PDF]
Biology, 2021 Rabbit hemorrhagic disease (RHD) causes high mortality and morbidity in European rabbits (Oryctolagus cuniculus). In Africa, the presence of the causative agent, the rabbit hemorrhagic disease virus (RHDV), was first confirmed in 1992 (genotype Lagovirus
Faten Ben Chehida +6 more
doaj +2 more sources
Comment on Shah et al. Genetic Characteristics and Phylogeographic Dynamics of Lagoviruses, 1988–2021. Viruses 2023, 15, 815 [PDF]
VirusesJoana Abrantes +2 more
exaly +4 more sources
Age and Infectious Dose Significantly Affect Disease Progression after RHDV2 Infection in Naïve Domestic Rabbits [PDF]
Viruses, 2021 Rabbit haemorrhagic disease virus 2 (RHDV2 or GI.2, referring to any virus with lagovirus GI.2 structural genes) is a recently emerged calicivirus that causes generalised hepatic necrosis and disseminated intravascular coagulation leading to death in ...
Robyn N. Hall +8 more
doaj +2 more sources
First Detection and Circulation of RHDV2 in New Zealand [PDF]
VirusesRabbit haemorrhage disease virus 2 (RHDV2) is a highly pathogenic lagovirus that causes lethal disease in rabbits and hares (lagomorphs). Since its first detection in Europe in 2010, RHDV2 has spread worldwide and has been detected in over 35 countries ...
Robyn N. Hall +4 more
doaj +2 more sources
Hepatobiliary organoids derived from leporids support the replication of hepatotropic lagoviruses
Journal of General Virology, 2023 The genus Lagovirus of the family Caliciviridae contains some of the most virulent vertebrate viruses known. Lagoviruses infect leporids, such as rabbits, hares and cottontails.
Egi Kardia +12 more
openaire +2 more sources
Transboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023 Rabbit hemorrhagic disease virus 2 (RHDV2 or Lagovirus europaeus GI.2) is spreading across North America. This has enabled submissions of lagomorphs for testing to veterinary diagnostic laboratories (VDLs). The liver is currently the gold‐standard sample type for testing by RT‐qPCR.
Javier Asin +7 more
wiley +1 more source