Results 51 to 60 of about 242 (213)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Aborto e democracia Abortion and democracy
A luta pela legalização do aborto pouco tem avançado no Brasil. O artigo observa a importância política da questão. Por um lado, é um índice da laicidade do Estado, que, por sua vez, é condição necessária para a vigência da democracia.
Luis Felipe Miguel
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
El Laicismo en el Islam ha separado a musulmanes sunníes y shíies, a los fundamentalistas de los liberales desde hace más de una centuria, como se ha evidenciado en etiquetas como ladiniya e ilmaniya.
Mustafa Akalay Nasser
doaj +2 more sources
Baskıcı Bir Laiklik Modeli Olarak Türk Laikliğinin Anatomisi
Türkiye uygulamış olduğu laiklik pratiği ile İslam dünyasında benzeri olmayan bir ülkedir. Ancak Türkiye’de kurumsallaşmış bulunan laiklik uygulamaları bu uygulamanın anavatanı olarak görülebilecek Batı toplumlarındaki uygulamalara da pek benzememektedir.
Mustafa Şan
doaj
Can Secularism Hinder Democracy? The Turkish Experiment
The concept of democracy that has gained importance since the end of the Second World War and the relation between state and religion in Turkey have attracted a considerable degree of interest in various academic circles.
Begüm Burak
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Les démoniaques dans l'art: Charcot and the "hysterical saints". [PDF]
Coutinho L +6 more
europepmc +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source

