Results 31 to 40 of about 923,611 (313)

A stable liquid crystal for electro-optical displays [PDF]

, 1972
Method is reported for substitution of hydroxy (OH) group ortho to anil linkage to stabilize anil-type liquid crystal for use in electro-optical ...
Lakes, M. M.
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Climate-dependent CO2 emissions from lakes [PDF]

, 2010
Inland waters, just as the world's oceans, play an important role in the global carbon cycle. While lakes and reservoirs typically emit CO2, they also bury carbon in their sediment.
Cole, J.J., Kosten, S., Mazzeo, N., Motta Marques, D.M.L., Da, Nes, E.H., van, Roland, F., Scheffer, M., Sternberg, L.S.L.   +7 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Recent occurrence of Cylindrospermopsis raciborskii, in Waikato lakes of New Zealand. [PDF]

, 2003
Cylindrospermopsis raciborskii is a toxin-producing species of cyanobacteria that in autumn 2003 was recorded for the first time in three shallow (max. depth ≤5 m) Waikato lakes and a hydro-electric dam on the Waikato River, New Zealand.
Antenucci J. P., Baker P. D., Barnes G. E., Cromarty P., Irwin J., Oliver R. L., Padisák J., Reynolds C. S., Utermöhl H.   +8 more
core   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Thornthwaite moisture index and depth of suction change under current and future climate ‒ An Australian study

Journal of Rock Mechanics and Geotechnical Engineering
Climate change is one of the major global challenges and it can have a significant influence on the behaviour and resilience of geotechnical structures.
Md Rajibul Karim, Bikash Devkota, Md Mizanur Rahman, Hoang Bao Khoi Nguyen   +3 more
doaj   +1 more source

Integrated experimental and technoeconomic evaluation of two-stage Cu-catalyzed alkaline–oxidative pretreatment of hybrid poplar

Biotechnology for Biofuels, 2018
Background When applied to recalcitrant lignocellulosic feedstocks, multi-stage pretreatments can provide more processing flexibility to optimize or balance process outcomes such as increasing delignification, preserving hemicellulose, and maximizing ...
Aditya Bhalla, Peyman Fasahati, Chrislyn A. Particka, Aline E. Assad, Ryan J. Stoklosa, Namita Bansal, Rachel Semaan, Christopher M. Saffron, David B. Hodge, Eric L. Hegg   +9 more
doaj   +1 more source

Potential Economic, Social and Environmental Contribution Study of Urban Agriculture Based on Five Key Features Identified through Past Studies

Land, 2023
Urban agriculture (UA), for recreational (gardening) and or commercial (farming) purposes, is commonly practised around the world, and uptake is increasing globally.
Arun Kafle, James Hopeward, Baden Myers
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source