Results 41 to 50 of about 341,185 (296)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Links to Lakes: the newsletter of the Arthur Lakes Library, No. 16, Spring 2000 [PDF]
, 2000 Links to Lakes was the newsletter of Colorado School of Mines Arthur Lakes Library from Spring 1992 through Fall ...
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Communications Biology, 2023 Plant derived bioactive small molecules have attracted attention of scientists across fundamental and applied scientific disciplines. We seek to understand the influence of these phytochemicals on rhizosphere and root-associated fungi.
Xingxing Li +3 more
doaj +1 more source
Links to Lakes: the newsletter of the Arthur Lakes Library, No. 20, Spring 2002 [PDF]
, 2002 Links to Lakes was the newsletter of Colorado School of Mines Arthur Lakes Library from Spring 1992 through Fall ...
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Links to Lakes: the newsletter of the Arthur Lakes Library, No. 2, Fall 1992 [PDF]
, 1992 Links to Lakes was the newsletter of Colorado School of Mines Arthur Lakes Library from Spring 1992 through Fall ...
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Arthur Lakes Library Quarterly eNewsletter, May, 2021 [PDF]
, 2021 The Arthur Lakes Library Quarterly eNewsletter contains the library's latest news and is published four times per year; it is available via email ...
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Extraction and Surface Activity of Australian Native Plant Extracts: Alphitonia excelsa
Colloids and InterfacesSaponin surfactants extracted from plants have significant potential applications in many industries. The interfacial properties of extracts of Alphitonia excelsa, a native Australian plant rich in saponins, have been characterised to assess their ...
Damien A. Sebben +7 more
doaj +1 more source