Results 51 to 60 of about 931,999 (314)

Recent occurrence of Cylindrospermopsis raciborskii, in Waikato lakes of New Zealand. [PDF]

, 2003
Cylindrospermopsis raciborskii is a toxin-producing species of cyanobacteria that in autumn 2003 was recorded for the first time in three shallow (max. depth ≤5 m) Waikato lakes and a hydro-electric dam on the Waikato River, New Zealand.
Antenucci J. P., Baker P. D., Barnes G. E., Cromarty P., Irwin J., Oliver R. L., Padisák J., Reynolds C. S., Utermöhl H.   +8 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Recent Advances and Perspectives on the Sources and Detection of Antibiotics in Aquatic Environments

Journal of Analytical Methods in Chemistry, 2022
Water quality and safety are vital to the ecological environment, social development, and ecological susceptibility. The extensive use and continuous discharge of antibiotics have caused serious water pollution; antibiotics are widely found in freshwater,
Yanbo Zeng, Fengqin Chang, Qi Liu, Lizeng Duan, Donglin Li, Hucai Zhang   +5 more
doaj   +1 more source

The decreasing level of Toshka Lakes seen from space [PDF]

, 2011
Toshka Lakes are lakes recently formed in the Sahara Desert of Egypt, by the water of the Nile, conveyed from the Nasser Lake through a canal in the Toshka Depression.
Sparavigna, Amelia Carolina
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Age and growth of longfinned eels (Anguilla dieffenbachii) in pastoral and forested streams in the Waikato River basin, and in two hydro-electric lakes in the North Island, New Zealand [PDF]

, 1993
Growth rates of New Zealand endemic longfinned eels (Anguilla dieffenbachii) from streams in pasture and indigenous forest, and from two hydroelectric lakes (Lakes Karapiro and Matahina), were estimated by otolith examination. Habitat-specific growth was
Aprahamian M. W., Aprahamian M. W., Balon E. K., Berg R., Boubee J. A. T., Burnet A. M. R., Burnet A. M. R., Cairns D., Cairns D., Chisnall B. L., Chisnall B. L., Chisnall B. L., Colombo G., Ford T. E., Hanchet S. M., Hanchet S. M., Helfman G. S., Helfman G. S., Hu L. C., Hurley D. A., Jearld A., Jellyman D. J., Jellyman D. J., Jellyman D. J., Jellyman D. J., Jellyman D. J., Jellyman D. J., Knights B., Livingston M. E., McEwan A., Mitchell C. P., Phillips C. J., Quinn J. M., Rossi R., Rounick J. S., Ryan P. A., Ryan P. A., Sinha V. R. P., Sloane R. D., Swales S., Todd P. R., Todd P. R., Umezawa A., Vollestad L. A., Wilkinson L.   +44 more
core   +2 more sources

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

BdCESA7, BdCESA8, and BdPMT utility promoter constructs for targeted expression to secondary cell-wall-forming cells of grasses

Frontiers in Plant Science, 2016
Utility vectors with promoters that confer desired spatial and temporal expression patterns are useful tools for studying gene and cellular function and for industrial applications.
Deborah ePetrik, Cynthia eCass, Dharshana ePadmakshan, Cliff eFoster, John eVogel, Steven eKarlen, John eRalph, John eSedbrook   +7 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Increasing the economic value of lignocellulosic stillage through medium-chain fatty acid production

Biotechnology for Biofuels, 2018
Background Lignocellulosic biomass is seen as an abundant renewable source of liquid fuels and chemicals that are currently derived from petroleum.
Matthew J. Scarborough, Griffin Lynch, Mitch Dickson, Mick McGee, Timothy J. Donohue, Daniel R. Noguera   +5 more
doaj   +1 more source