Results 51 to 60 of about 923,611 (313)

Sensing of Substrate Vibrations in the Adult Cicada Okanagana rimosa (Hemiptera: Cicadidae) [PDF]

open access: yes, 2018
Detection of substrate vibrations is an evolutionarily old sensory modality and is important for predator detection as well as for intraspecific communication. In insects, substrate vibrations are detected mainly by scolopidial (chordotonal) sense organs
Alt, Joscha A., Lakes-Harlan, Reinhard
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Extraction and Surface Activity of Australian Native Plant Extracts: Alphitonia excelsa

open access: yesColloids and Interfaces
Saponin surfactants extracted from plants have significant potential applications in many industries. The interfacial properties of extracts of Alphitonia excelsa, a native Australian plant rich in saponins, have been characterised to assess their ...
Damien A. Sebben   +7 more
doaj   +1 more source

Recent Advances and Perspectives on the Sources and Detection of Antibiotics in Aquatic Environments

open access: yesJournal of Analytical Methods in Chemistry, 2022
Water quality and safety are vital to the ecological environment, social development, and ecological susceptibility. The extensive use and continuous discharge of antibiotics have caused serious water pollution; antibiotics are widely found in freshwater,
Yanbo Zeng   +5 more
doaj   +1 more source

The decreasing level of Toshka Lakes seen from space [PDF]

open access: yes, 2011
Toshka Lakes are lakes recently formed in the Sahara Desert of Egypt, by the water of the Nile, conveyed from the Nasser Lake through a canal in the Toshka Depression.
Sparavigna, Amelia Carolina
core   +1 more source

Importance of long-term cycles for predicting water level dynamics in natural lakes [PDF]

open access: yes, 2015
Lakes are disproportionately important ecosystems for humanity, containing 77% of the liquid surface freshwater on Earth and comprising key contributors to global biodiversity.
Brennan, Michael   +3 more
core   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

BdCESA7, BdCESA8, and BdPMT utility promoter constructs for targeted expression to secondary cell-wall-forming cells of grasses

open access: yesFrontiers in Plant Science, 2016
Utility vectors with promoters that confer desired spatial and temporal expression patterns are useful tools for studying gene and cellular function and for industrial applications.
Deborah ePetrik   +7 more
doaj   +1 more source

Investigation of thermal regimes of lakes used for water supply and examination of drinking water system in Kotzebue, Alaska [PDF]

open access: yes, 2012
Thesis (M.S.) University of Alaska Fairbanks, 2012Many villages in Arctic Alaska rely on lakes for water supply, such as the Alaskan City of Kotzebue, and these lakes may be sensitive to climate variability and change, particularly thermal regimes and ...
Bendlova, Tereza
core  

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