Results 51 to 60 of about 116,803 (294)

The long noncoding RNA LAL contributes to salinity tolerance by modulating LHCB1s’ expression in Medicago truncatula

open access: yesCommunications Biology
Long non-coding RNAs (lncRNAs) are abundant in plants, however, their regulatory roles remain unclear in most biological processes, such as response in salinity stress which is harm to plant production.
Yang Zhao   +6 more
doaj   +1 more source

Triagem de Deficiência de Lipase Ácida Lisossômica em uma Unidade Clínica de Dislipidemias

open access: yesArquivos Brasileiros de Cardiologia
Resumo Fundamento A deficiência da lipase ácida lisossômica (D-LAL) é uma doença autossômica recessiva rara, caracterizada pelo acúmulo maciço de ésteres de colesterol e triglicerídeos em vários órgãos, levando à hepatosplenomegalia, esteatose ...
Zenia Brasil   +12 more
doaj   +2 more sources

Hepatic lysosomal acid lipase overexpression worsens hepatic inflammation in mice fed a Western diet

open access: yesJournal of Lipid Research, 2021
Nonalcoholic fatty liver disease (NAFLD) is characterized by the accumulation of lipid droplets in hepatocytes. NAFLD development and progression is associated with an increase in hepatic cholesterol levels and decreased autophagy and lipophagy flux ...
Michael W. Lopresti   +7 more
doaj   +1 more source

IICA en Acción. Especial. Entrevista de Rattan Lal, parte ll

open access: yes, 2022
Participantes: Carolina Brunstein, locutora. Rattan Lal, Nobel de la Paz y Premio Mundial de Alimentación 2020.Fragmentos de una entrevista con el profesor Lal, discutiendo la importancia de los suelos ...
Instituto Interamericano de Cooperación para la Agricultura (IICA)   +2 more
core  

Mesoporous PU/PEDOT:PSS Electrodes Reveal Population‐Level Stochastic Bioelectrical Dynamics in Marine Diatoms

open access: yesAdvanced Science, EarlyView.
Mesoporous mixed ionic‐electronic PU/PEDOT: PSS electrodes enable label‐free detection of stochastic extracellular bioelectrical dynamics in living Phaeodactylum tricornutum. Living diatoms actively modulate interfacial ionic dynamics, establishing stochastic electrochemical noise as a sensitive probe of microbial bioelectrochemical activity and a new ...
David M. S. Silva   +7 more
wiley   +1 more source

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

open access: yesAdvanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun   +18 more
wiley   +1 more source

Would You Figure It Out? Differential Diagnoses: Beyond the Usual [PDF]

open access: yesEuropean Medical Journal Hepatology, 2015
The Synageva BioPharma-sponsored symposium discussed the differential diagnoses for liver diseases that may be under-recognised in clinical settings, with a focus on lysosomal acid lipase deficiency (LAL D).
Vlad Ratziu   +4 more
doaj  

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

open access: yesAdvanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang   +5 more
wiley   +1 more source

Mohan Lal : Activism against Caste in India and Canada

open access: yes, 2021
This interview is part of the “Caste in Canada” oral history project. “Caste in Canada” comprises interviews with nineteen Canadians of Dalit background, documenting their histories, experiences, and understanding of the implications of caste in Canada ...
Lal, Mohan   +2 more
core  

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

open access: yesAdvanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou   +12 more
wiley   +1 more source

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