Results 71 to 80 of about 116,803 (294)

Cooperative learning strategies to raise attainment in mathematics with pupils aged 11–16 years: A systematic literature review

British Educational Research Journal, EarlyView.
Abstract Cooperative learning is a widely adopted teaching method to improve academic achievement. This review synthesises existing research on the use of cooperative learning within a school setting for pupils aged 11–16 years. Such a review has not been undertaken to date and will present an evidence base for educators considering implementation ...
Patricia Hampson, Zhe. Li, Allen Thurston   +2 more
wiley   +1 more source

Loss or inhibition of lysosomal acid lipase in vitro leads to cholesteryl ester accumulation without affecting muscle formation or mitochondrial function

BBA Advances
Skeletal muscle (SM) is essential for movement, stability, and overall body function, and it readily adapts to changes in energy demand. Myogenesis is energy-intensive and involves complex molecular and cellular events.
Alena Akhmetshina, Laszlo Schooltink, Melina Amor, Katharina B. Kuentzel, Silvia Rainer, Ananya Nandy, Hansjoerg Habisch, Tobias Madl, Elizabeth Rendina-Ruedy, Katharina Leithner, Nemanja Vujić, Dagmar Kratky   +11 more
doaj   +1 more source

The therapeutic response and clinical outcome of adults with ALL1(MLL)/AF4 fusion positive acute lymphoblastic leukemia according to the GIMEMA experience

Haematologica, 2010
The clinical outcome of 21 adults with ALL1(MLL)/AF4 positive acute lymphoblastic leukemia enrolled in the GIMEMA LAL 2000 trial and of 25 patients entered into the previous 0496 study is reported.
Giuseppe Cimino, Natalia Cenfra, Loredana Elia, Simona Sica, Mario Luppi, Giovanna Meloni, Marco Vignetti, Francesca Paoloni, Robin Foà, Franco Mandelli   +9 more
doaj   +1 more source

Lysosomal acid lipase, CSF1R, and PD-L1 determine functions of CD11c+ myeloid-derived suppressor cells

JCI Insight, 2022
Lysosomal acid lipase (LAL) is a key enzyme in the metabolic pathway of neutral lipids. In the blood of LAL-deficient (Lal–/–) mice, increased CD11c+ cells were accompanied by upregulated programmed cell death ligand 1 (PD-L1) expression. Single-cell RNA
Ting Zhao, Sheng Liu, Xinchun Ding, Erica M. Johnson, Nasser H. Hanna, Kanhaiya Singh, Chandan K. Sen, Jun Wan, Hong Du, Cong Yan   +9 more
doaj   +1 more source

Beyond Carbon: Corporate Environmental Performance Across Multiple Domains

Business Strategy and the Environment, EarlyView.
ABSTRACT We examine corporate environmental performance (CEP) as a multidimensional system rather than isolated outcomes. Combining institutional and behavioral perspectives, we analyze four domains—CO2 emissions, waste, energy, and water—using S&P 500 firms that disclosed data on all four domains (2006–2024).
Rei Uchida, Murali Chari
wiley   +1 more source

The yield of Limulus amoebocyte lysate (LAL), which is used for endotoxin detection and adjunct diagnosis of invasive fungal infection, was optimized with caffeine collection buffer

Frontiers in Microbiology
BackgroundLimulus amoebocyte lysate (LAL) is a major component of the Fungal Infection Diagnosis Kit for the adjunct diagnosis of invasive fungal infections.
Sophia Zhang, Mengmeng Zhang, Jessica Zhang   +2 more
doaj   +1 more source

Climate Change Exposure and Firms' Biodiversity Impact Reduction Strategy

Business Strategy and the Environment, EarlyView.
ABSTRACT This paper investigates how climate change exposure shapes long‐run biodiversity disclosure strategies, for instance, by informing efforts to reduce biodiversity impacts and by contributing to the existing environment and strategy literature in various ways. First, this paper adds insight into horizon issues related to climate change and shows
Post Raj Pokharel
wiley   +1 more source

PHIL Accelerator at LAL - Diagnostic status

, 2010
http://accelconf.web.cern.ch/AccelConf/BIW2010/papers/tupsm100.pdfInternational audienceThe "Photo-Injector at LAL" (PHIL : http://phil.lal.in2p3.fr/) is a new electron beam accelerator at LAL.
Letourneur, S., Prevost, C., Blot, F., Variola, A., Gonnin, A., Brossard, J., Joré, M., Roux, R., Cavalier, S., Lepercq, P., Mercier, B., Monard, H.   +11 more
core   +2 more sources

Lanifibranor Reduces Inflammation and Improves Dyslipidemia in Lysosomal Acid Lipase-Deficient Mice

Gastro Hep Advances
Background and Aims: Recent studies showed that patients suffering from lysosomal acid lipase deficiency (LAL-D) benefit from enzyme replacement therapy; however, liver histopathology improved in some but not all patients.
Ivan Bradić, Nemanja Vujić, Katharina B. Kuentzel, Hansjörg Habisch, Anita Pirchheim, Alena Akhmetshina, John D. Henderson, Tobias Madl, Atul S. Deshmukh, Dagmar Kratky   +9 more
doaj   +1 more source

Reduced Lysosomal Acid Lipase Activity in Adult Patients With Non-alcoholic Fatty Liver Disease

EBioMedicine, 2015
Non-alcoholic fatty liver disease (NAFLD) is characterized by intra-hepatic fat accumulation and mechanisms involved in its pathogenesis are not fully explained. Lysosomal Acid Lipase (LAL) is a key enzyme in lipid metabolism.
Francesco Baratta, Daniele Pastori, Maria Del Ben, Licia Polimeni, Giancarlo Labbadia, Serena Di Santo, Fiorella Piemonte, Giulia Tozzi, Francesco Violi, Francesco Angelico   +9 more
doaj   +1 more source