Results 181 to 190 of about 79,468 (267)

A Highly Conserved SNARE‐Associated Protein Enhances Plant Immunity by Regulating Vesicle Trafficking

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3426-3440, May 2026.
ABSTRACT The plant endomembrane system and vesicle trafficking are central to plant immunity, mediating the targeted delivery and recycling of defence molecules during pathogen attack. Here, we investigated the functional role of soybean Vacuole Membrane Protein 1 (GmVMP1) in mediating resistance against soybean cyst nematode (SCN, Heterodera glycines).
Tracy E. Hawk, Peitong Li, Hafiz Muhammad Khalid Abbas, Mst Shamira Sultana, Sarbottam Piya, Nicole Coffey, Cengizhan Öztürk, Sobhan Bahrami Zadegan, Susan Thomas Laird, Mazen Alazem, Samantha P. Nuzzi, J. Hollis Rice, Chris Wyman, Tessa Burch‐Smith, Vince Pantalone, Tarek Hewezi   +15 more
wiley   +1 more source

Variable A-type lamin expression in Merkel cell carcinoma cell lines and its association with nuclear integrity. [PDF]

Sci Rep
Stiekema M, van Gorp C, Macamo A, Hausen AZ, van Zandvoort MAMJ, Ramaekers FCS, Broers JLV.   +6 more
europepmc   +1 more source

Development of Styryl‐Modified 3,4‐Dihydropyrimidin‐2(1H)‐ones as Potential Antitumor Agents

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Styryl‐modified 3,4‐dihydropyrimidin‐2(1H)‐ones (DHPMs), designed from the Eg5 inhibitor monastrol, show markedly enhanced antiproliferative activity in HeLa and MCF‐7 cancer cells. Lead compounds 16 and 17 trigger apoptosis through cell‐line‐specific pathways and downregulate c‐Myc, emerging as promising anticancer candidates.
Konstantinos Panagoulias, Woonghee Kim, Murat Ozdemir, Busra Turan, Adil Mardinoglu, Hasan Turkez, Daniela Trisciuzzi, Orazio Nicolotti, Antonio Di Stefano, Stamatia Vassiliou, Ivana Cacciatore   +10 more
wiley   +1 more source

Roles of DNA Damage Response Pathway in the Regulation of the Nuclear Envelope. [PDF]

Curr Issues Mol Biol
Kamikawa Y, Wu Z, Fujise K, Imaizumi K, Saito A.   +4 more
europepmc   +1 more source

Attenuated lamin A-prohibitin2 interaction leads to mitochondrial dysfunction in LMNA 289 A>G-mediated dilated cardiomyopathy. [PDF]

J Biol Chem
Nath S, Prusty D, Islam SR, Manna SK, Sengupta K.   +4 more
europepmc   +1 more source

The responsive nucleus: morphological signatures of cellular state. [PDF]

Nucleus
Pérez-Venteo A, Bosch-Calvet M, Garcia-Cajide M, Mauvezin C.   +3 more
europepmc   +1 more source

B-type lamins maintain transcriptional homeostasis by spatially controlling chromatin-speckle proximity. [PDF]

Nucleic Acids Res
Shin GS, Kim J, Kim JY, Kim CH, An MJ, Lee HM, Jo AR, Park Y, Hwangbo Y, Hong TK, Jung YS, Rhee S, Kim JW.   +12 more
europepmc   +1 more source

Novel PMVs/ZIP4/Zinc/Prelamin A Axis Promotes Nuclear Dysmorphism and Vascular Aging in Humans and Rodents Post-Injury: Effective Treatment With Platelet Membrane-Coated ZIF-8 Nanoparticles. [PDF]

Aging Cell
Ma T, Bao H, Xu Z, Ren H, Tian W, Chen J, Liu Z, Lu X, Lv F, Yao Q, Qi Y, Huang K.   +11 more
europepmc   +1 more source

MMP-3 cleavage of Lamin A induces pro-migratory nuclear deformity, nucleophagy, and their autophagic secretion with extracellular vesicles in metastatic cancer. [PDF]

Cell Commun Signal
Eguchi T, Taha EA, Nakano K, Tiwari V, Takebe K, Inoue T, Xing L, Sogawa C, Okamoto K, Calderwood SK.   +9 more
europepmc   +1 more source

Changes in nuclear and actin mechanics from G1 to G2 affect nuclear integrity. [PDF]

J Cell Sci
Bunner S, Huang K, Shah A, Figueroa S, Lang N, Chu C, Eskndir N, Pho M, Manning G, Zheng M, Fritz-Laylin L, Velle KB, Marcus J, Orth J, Stephens AD.   +14 more
europepmc   +1 more source